Genomics

RSS

Differences in geographic origin of genes may affect mitochondrial function

Differences in the geographic origin of genes may affect the function of human mitochondria--energy-generating organelles inside of cells--according to a new study.

14 Jan 2019

Identifying genetic factors that lead to squamous cell carcinoma

Skin cancer is on the rise in the United States. Squamous cell carcinoma, the second most common form of cancer in the U.S., has the highest mortality rate of all non-melanoma skin cancers. In roughly two to five percent of patients, the disease will metastasize and spread throughout the body, making it difficult to treat.

14 Jan 2019

Genetic variants linked with risk tolerance and risky behaviors

As part of an international research project, a group of scientists from the University of Zurich found genetic variants associated with risk tolerance and risky behaviors. It is one of the first studies to link genetic variants with behavioral outcomes, which are relevant to social science research.

14 Jan 2019

Plan your Pittcon 2019 with the mobile app

The Pittcon marketing department is excited to announce the release of its official conference and exposition mobile app, Pittcon 2019.

From Pittcon 14 Jan 2019

Conducting ChIP-Seq with Low Cell Numbers

An interview with Dr. Kathyrn Cunningham at SfN 2018, providing advice on carrying out Chromatin Immunoprecipitation Sequencing (ChIP-seq) with low cell numbers.

From Active Motif 14 Jan 2019

Researchers repurpose gene-editing tool CRISPR to develop better antibiotics

A University of Wisconsin-Madison researcher and his collaborators at the University of California, San Francisco have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones.

11 Jan 2019

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of Cas9-fusion proteins for diverse applications beyond simple DNA cutting, such as base editing and epigenetic modifications.

11 Jan 2019

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

UCLA researchers led by Dr. Donald Kohn have created a method for modifying blood stem cells to reverse the genetic mutation that causes a life-threatening autoimmune syndrome called IPEX.

11 Jan 2019

New generation of chemists conducts research to further understand complex nature of lipids

The post-holiday New Year might not seem like an ideal time to celebrate fat. But when it comes to lipids, there is no better time.

11 Jan 2019

Bacteria on the International Space Station are adapting to survive, not to harm

Mutant bacteria stranded in space by visiting astronauts have been adapting to survive in their new environment, according to a new study.

10 Jan 2019

NYSCF announce partnership with Ngene to develop new disease treatments

The New York Stem Cell Foundation Research Institute today announced a partnership with Ngene Therapeutics Inc. to develop new disease treatments that leverage human stem cell research and novel gene editing techniques.

10 Jan 2019

Protein discovery could lead to mosquito "birth control"

Researchers have discovered a way of preventing mosquito eggs from hatching, paving the way for drugs that could serve as “birth control” within mosquito populations.

9 Jan 2019

New mechanism of gene regulation involved in tumor progression discovered

Genes contain all the information needed for the functioning of cells, tissues, and organs in our body. Gene expression, meaning when and how are the genes being read and executed, is thoroughly regulated like an assembly line with several things happening one after another.

9 Jan 2019

Early life stress in mice affects their offspring behavior

Russian neuroscientists discovered that the stress experienced by mice during their first weeks of life, affects not only them but also their offspring. The obtained data will help to understand how negative experience in the early period of life affects the mammalian brain.

8 Jan 2019

Scientists explore bacterial immunity to better understand infectious disease

Patients with cystic fibrosis are often infected by pseudomonas aeruginosa, a bacterium that infects the lungs and prevents breathing, often causing death.

8 Jan 2019

New molecular engineering method improves precision of biomarker analysis

Researchers from the University of Helsinki in cooperation with the University of Tartu, Competence Centre on Health Technologies from Estonia, and the Karolinska Institute, published an article in Nature's partner journal Genomic Medicine in which they present Targeted Allele Counting by sequencing along with several of its potential applications.

8 Jan 2019