Genomics

RSS

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of neurological disease, today announced data demonstrating that genetic inhibition of SARM1 prevents axonal degeneration in the central, ocular and peripheral nervous systems.

5 Nov 2018

New research explains how large virus shells are formed

A virus, the simplest physical object in biology, consists of a protein shell called the capsid, which protects its nucleic acid genome -- RNA or DNA. The capsid can be cylindrical or conical in shape, but more commonly it assumes an icosahedral structure, like a soccer ball.

5 Nov 2018

Horizon Discovery collaborates with Biocartis to offer reference standards for new Idylla MSI assay

Horizon Discovery Group plc, a global leader in gene editing and gene modulation technologies, today announces that it has developed a set of precisely defined cell line-derived reference standards to support Biocartis’ recently launched Idylla™ microsatellite instability Assay.

From Revvity 5 Nov 2018

Scientists decode the longest ever continuous DNA sequence

Scientists have decoded the longest continuous DNA sequence to date, measuring around 10,000 times longer than normal sequencing reads.

1 Nov 2018

Researchers uncover confusion and gaps in study participants’ understanding of genetic privacy

Confusion and ambiguity in how U.S. patients and researchers perceive genetic privacy is uncovered by a study published October 31, 2018 in the open-access journal PLOS ONE by Ellen W. Clayton from Vanderbilt University, USA, and colleagues.

1 Nov 2018

CNIO researchers link MASTL protein to origin of thrombocytopenia

The Cell Division and Cancer Group of the Spanish National Cancer Research Centre has discovered that MASTL, the protein whose function in the organism has not yet been sufficiently investigated, plays an important role in controlling the cytoskeleton, the structure that gives shape to the cells, and enables their mobility and capacity for grouping.

1 Nov 2018

Genetic defect linked to ALS causes sugar-starved cells to overproduce lipids

A genetic defect tied to a variety of neurodegenerative diseases and mental illnesses changes how cells starved of sugar metabolize fatty compounds known as lipids, a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health shows.

31 Oct 2018

Study explores impact of new Texas law HB 810 on stem cell interventions

A new study takes a close look at the content and potential implications of the new Texas law HB 810, which aims to expand assess of experimental stem cell interventions outside the realm of clinical trials under FDA oversight.

31 Oct 2018

Study: Single protein regulates network of genes essential for sperm development

A single protein regulates a battery of key genes inside developing sperm, according to a new study out of Case Western Reserve University School of Medicine.

31 Oct 2018

Growth of genomic databases hinders efforts to identify bacteria

There are many ways to slice and dice genomic data to identify a species of bacteria, or at least find its close relatives. But fast techniques to sequence genomes have flooded the public databases and in a biased fashion, containing lots of genomic data about some species and not enough about others, according to a Rice University computer scientist.

31 Oct 2018

Top researchers call for unified standards in 3D genome and epigenetic data

Studying the three-dimensional structure of DNA and its dynamics is revealing a lot of information about gene expression, expanding our knowledge of how cells, tissues and organs actually work in health and disease.

30 Oct 2018

Using genome editing to prevent sudden cardiac death

Each year, at least 3 million people worldwide die of sudden cardiac death. In the U.S., this number reaches up to 450,000 people.

30 Oct 2018

Study provides a new way of thinking about cold stress in plants

When temperatures drop, plants can't bundle up. Stuck outside, exposed, plants instead undergo a series of biochemical changes that protect cells from damage.

29 Oct 2018

Barcelona researchers win one of the most prestigious EU grants to study CLL

The European Research Council today announced the results of the 2018 Synergy Grants call for proposals. The aim of Synergy Grants is to address ambitious research questions that can only be answered by the coordinated work of a small group of two to four principal investigators and their teams, bringing together their complementary skills, knowledge and resources.

26 Oct 2018

Molecular breakthrough may improve prognosis for pancreatic cancer

Scientists have discovered a method by which fibroblasts in the stroma of pancreatic tumors can be reprogrammed to suppress tumor cell growth.

26 Oct 2018

Skin cells show minimal damage, maximum pigmentation when exposed to sunlight every 48 hours

Skin cells show the least amount of DNA damage and produce the most amount of melanin when exposed to sunlight in 48 hour windows, according to new study.

25 Oct 2018

'Cancer Gene Census' could help find drug targets and design treatments

Researchers at the Wellcome Sanger Institute have created the first comprehensive summary of all genes known to be involved in human cancer, the "Cancer Gene Census". Describing all genes strongly implicated in causing cancer, the Census also describes how they function across all forms of this disease.

25 Oct 2018