Genomics

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UW-Madison researcher explores how female fertility is affected by development of the ovary in mice

When Joan Jorgensen was an undergraduate at the University of Wisconsin–Madison, her roommate confided that she had just one period before going through menopause in high school.

3 Aug 2018

Genome-wide association study identifies 151 genes for atrial fibrillation

Drawing on genomic data from more than one million individuals, researchers from the University of Michigan have led a large collaborative effort to discover as-yet unknown genetic risk factors for atrial fibrillation: an irregular, often rapid heart rate affecting millions of Americans and more than 30 million people worldwide.

3 Aug 2018

Scientists map regulatory landscape of mouse genome at single-cell resolution

Scientists have completed a major effort to map the regulatory landscape of the mouse genome at a single-cell resolution.

2 Aug 2018

MGH researchers explore how genetic abnormality in Ewing sarcoma unleashes tumor growth

A Massachusetts General Hospital research team has used epigenome editing tools to investigate how the genetic abnormality that drives Ewing sarcoma - the second most common bone cancer in children and young adults - unleashes tumor growth.

2 Aug 2018

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

A group of researchers at the University of São Paulo in Brazil used a DNA editing tool called CRISPR/Cas9 to manipulate on of the genes associated to the autoaggressive T lymphocytes responsible for inducing autoimmune diseases such as autoimmune polyglandular syndrome type 1 and type 1 diabetes.

2 Aug 2018

Innovative 'EvolvR' system lets scientists shuffle genes until they get right variation

Scientists at the Innovative Genomics Institute have concocted a transformative new way to harness the power of evolution.

2 Aug 2018

Tumor suppressor gene PTEN may be potential Achilles heel for breast cancer cells

In an article published July 17, 2018 by Nature Communications, a highly collaborative team of researchers at the Medical University of South Carolina and Ohio State University report that normal breast cells can prevent successful radiation treatment of breast cancer due to dysregulation between tumor suppressors and oncogenes.

2 Aug 2018

Breakthrough in stem cell research could lead to cure for cystic fibrosis

Researchers have successfully proved that gene therapy can be used to convert adult stem cells into functioning lung cells for the treatment of cystic fibrosis

2 Aug 2018

Researchers reveal molecular mechanisms that make people with EV prone to ß-HPVs

Keratinocyte skin cells are common targets of the beta subtype of human papilloma virus. This usually harmless infection causes skin disease in people with rare gene mutations.

2 Aug 2018

New method tags breast implants with tomato DNA to prevent counterfeiting

For years, a French company sold breast implants made of cheap industrial silicone components. Headline news when it broke in 2010, this scandal is still keeping the courts busy today.

2 Aug 2018

Computer simulations can accurately predict transmission of HIV

In a recently published study in the journal Nature Microbiology, researchers at Los Alamos National Laboratory show that computer simulations can accurately predict the transmission of HIV across populations, which could aid in preventing the disease.

1 Aug 2018

Researchers use guide RNAs to improve base editing system

Researchers have used guide RNAs to improve the adenine base editing (ABE) system, used by scientists to alter genetic codes in animal models of disease.

1 Aug 2018

Father’s genes can affect quality of maternal care received by a newborn

A father’s genes are no longer thought to just provide a blueprint for the growth and development of their offspring.

1 Aug 2018

New DNA test predicts how humans may respond to cannabis

Today marks the launch of the Endocanna Health "Cannabinoid DNA Variant Test" the most comprehensive personalized cannabis DNA test available on the market today.

1 Aug 2018

Mutation 'hotspots' in DNA could help determine cancer risk

Researchers have identified DNA 'hotspots' where gene mutations are significantly more likely to arise. The findings will be used to determine cancer risk.

31 Jul 2018

Researchers sequence complete mitochondrial genome of malaria mosquitoes

A team led by scientists from the Johns Hopkins Bloomberg School of Public Health has sequenced and annotated the first complete mitochondrial genome of Anopheles funestus, one of the main vectors of malaria in sub-Saharan Africa.

31 Jul 2018

Gene linked to hair loss could be exploited to improve cancer immunotherapy

A gene that's associated with an autoimmune form of hair loss could be exploited to improve cancer immunotherapy, suggests a new mouse study by Columbia University Irving Medical Center (CUIMC) researchers.

31 Jul 2018

New study explores human T cell function under inflammatory conditions

The Marshall University School of Pharmacy, in collaboration with the Marshall University Joan C. Edwards School of MedicineGenomics Core, recently released a new study that explores human T cell function under inflammatory conditions.

31 Jul 2018

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Despite high hopes and high investment in CRISPR-Cas9 gene editing, scientists still have a lot to learn about how it works in humans.

31 Jul 2018

Bt modification in maize does not affect beneficial microorganisms

Bt modification in maize does not affect non-target beneficial microorganisms such as endophytes. Although Bt maize is one of the most popular GM crops in the world, little is known about potential impacts on ecosystem functionalities.

30 Jul 2018

Genomics

UW-Madison researcher explores how female fertility is affected by development of the ovary in mice

Genome-wide association study identifies 151 genes for atrial fibrillation

Scientists map regulatory landscape of mouse genome at single-cell resolution

MGH researchers explore how genetic abnormality in Ewing sarcoma unleashes tumor growth

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

Innovative 'EvolvR' system lets scientists shuffle genes until they get right variation

Tumor suppressor gene PTEN may be potential Achilles heel for breast cancer cells

Breakthrough in stem cell research could lead to cure for cystic fibrosis

Researchers reveal molecular mechanisms that make people with EV prone to ß-HPVs

New method tags breast implants with tomato DNA to prevent counterfeiting

Computer simulations can accurately predict transmission of HIV

Researchers use guide RNAs to improve base editing system

Father’s genes can affect quality of maternal care received by a newborn

New DNA test predicts how humans may respond to cannabis

Mutation 'hotspots' in DNA could help determine cancer risk

Researchers sequence complete mitochondrial genome of malaria mosquitoes

Gene linked to hair loss could be exploited to improve cancer immunotherapy

New study explores human T cell function under inflammatory conditions

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Bt modification in maize does not affect beneficial microorganisms

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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