Genomics

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Imaging study shows how junk DNA activates genes

Researchers at Princeton University have used video imaging to capture the process by which junk DNA activates genes.

23 Jul 2018

Researchers investigate recessive genetic disorder that leads to childhood blindness

Our genome is made up of 20,000 genes, all of which may cause disease. At present, 4,141 genes have been identified as being responsible for genetic abnormalities, leaving around 16,000 genes with unknown implication in disease.

23 Jul 2018

Study: Genes have no effect on consumption of total calories, carbohydrates, fat

Individualized dietary recommendations based on genetic information are currently a popular trend. A team at the Technical University of Munich has systematically analyzed scientific articles and reached the following conclusion: There is no clear evidence for the effect of genetic factors on the consumption of total calories, carbohydrates, and fat

23 Jul 2018

Sage launches new web-based tool that helps explore curated genomic analyses of Alzheimer's

Sage Bionetworks announces the launch of the Agora platform an interactive, web-based tool that allows researchers to explore curated genomic analyses of Alzheimer's Disease, including a list of early candidate target nominations for AD.

20 Jul 2018

Researchers uncover cause for progression of prostate cancer to incurable stage

Researchers at the University of Oulu in Finland have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism rs11672691 influences prostate cancer aggressiveness.

20 Jul 2018

Gene therapy may hold potential to treat people with spinal cord injuries

Delivering a single injection of a scar-busting gene to the spinal cord of rats following injury promotes the survival of nerve cells and improves hind limb function within weeks, according to a study published April 2 in The Journal of Neuroscience.

20 Jul 2018

Genetic sequencing reveals new clues to aggressiveness of prostate cancer

Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common.

20 Jul 2018

Genome research suggests presence of enteric fever in medieval Europe

Genome research conducted by the University of Warwick suggests that enteric fever, a potentially lethal disease more commonly found in hot countries, was present in medieval Europe.

20 Jul 2018

Researchers raise viability of cloned mice using somatic cell nuclear transfer method

An international group of researchers have raised the viability of mice that were cloned using a method called somatic cell nuclear transfer, by stimulating two epigenetic factors, and by doing this have shown that creating cloned animals more efficiently will require further work in the area of epigenetics.

20 Jul 2018

Novel tool predicts genes that cause disease due to production of truncated proteins

Predicting genes that can cause disease due to the production of truncated or altered proteins that take on a new or different function, rather than those that lose their function, is now possible thanks to an international team of researchers, including researchers from Baylor College of Medicine, that has developed a new analytical tool to effectively and efficiently predict such candidate genes.

20 Jul 2018

Researchers to study molecular mechanisms behind susceptibility of males to autism

Neurodevelopmental disorders such as autism spectrum disorder and intellectual disability are more prevalent in males than females.

20 Jul 2018

TGen opens tissue donation portal to advance DIPG research

A tissue donation portal opened today at the Translational Genomics Research Institute (TGen), which will advance research towards new treatments for an aggressive brain cancer that mostly strikes young children.

19 Jul 2018

Study uncovers new protein complex that shields broken DNA ends

Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer.

19 Jul 2018

Study finds link between DNA methylation and non-alcoholic fatty liver disease

DNA methylation is a molecular process that helps enable our bodies to repair themselves, fight infection, get rid of environmental toxins, and even to think. But sometimes this process goes awry.

19 Jul 2018

Study identifies RNA molecules that regulate male hormones in prostate cancer

In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone.

19 Jul 2018

Researchers identify subtypes of retinal ganglion cells using single-cell RNA sequencing

Single-cell sequencing technologies are filling in fine details in the catalog of life. Researchers at the University of Connecticut Health Center and The Jackson Laboratory have identified 40 subtypes of retinal ganglion cells along with the genetic markers and transcription factors that differentiate them.

19 Jul 2018

Deleting single gene in gut bacteria affects metabolism, reduces weight gain in mice

Scientists have found that deleting a single gene in a particular strain of gut bacteria causes changes in metabolism and reduced weight gain in mice, according to a study in the journal eLife.

18 Jul 2018

Researchers identify key protein involved in irregular brain cell activity

In a new study in mice, researchers have identified a key protein involved in the irregular brain cell activity seen in autism spectrum disorders and epilepsy. The protein, p53, is well-known in cancer biology as a tumor suppressor.

17 Jul 2018

Large international study finds new risk genes for hay fever

In a large international study involving almost 900,000 participants, researchers from the University of Copenhagen and COPSAC have found new risk genes for hay fever. It is the largest genetic study so far on this type of allergy, which affects millions of people around the world.

17 Jul 2018

FAU and partners receive NIH research grant to shed light on sleep loss and metabolic disorders

A neuroscientist from Florida Atlantic University's Jupiter Life Science Initiative and collaborators from the University of Minnesota and Stowers Institute for Medical Research recently a received a four-year, $1.68 million R01 research grant from the National Institutes of Health's National Institute of General Medical Sciences for a project titled, "Understanding Complex Trait Architecture through Population Genomics."

17 Jul 2018

Genomics

Imaging study shows how junk DNA activates genes

Researchers investigate recessive genetic disorder that leads to childhood blindness

Study: Genes have no effect on consumption of total calories, carbohydrates, fat

Sage launches new web-based tool that helps explore curated genomic analyses of Alzheimer's

Researchers uncover cause for progression of prostate cancer to incurable stage

Gene therapy may hold potential to treat people with spinal cord injuries

Genetic sequencing reveals new clues to aggressiveness of prostate cancer

Genome research suggests presence of enteric fever in medieval Europe

Researchers raise viability of cloned mice using somatic cell nuclear transfer method

Novel tool predicts genes that cause disease due to production of truncated proteins

Researchers to study molecular mechanisms behind susceptibility of males to autism

TGen opens tissue donation portal to advance DIPG research

Study uncovers new protein complex that shields broken DNA ends

Study finds link between DNA methylation and non-alcoholic fatty liver disease

Study identifies RNA molecules that regulate male hormones in prostate cancer

Researchers identify subtypes of retinal ganglion cells using single-cell RNA sequencing

Deleting single gene in gut bacteria affects metabolism, reduces weight gain in mice

Researchers identify key protein involved in irregular brain cell activity

Large international study finds new risk genes for hay fever

FAU and partners receive NIH research grant to shed light on sleep loss and metabolic disorders

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