Genomics

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Widespread transfer of genes between species appears to be key driver of evolution

Far from just being the product of our parents, University of Adelaide scientists have shown that widespread transfer of genes between species has radically changed the genomes of today's mammals, and been an important driver of evolution.

9 Jul 2018

Single-cell RNA sequencing reveals how complex brain circuit works

The complexity of the human brain presents scientists with immense challenges as they try to find new treatments for a host of diseases and conditions. But the advent of a new technology known as single-cell RNA sequencing is opening a window into how the brain works.

6 Jul 2018

Study finds common risk gene for both job-related exhaustion in shift workers and Alzheimer's

A Finnish study published in the respected SLEEP journal shows that a variation in the melatonin receptor 1A (MTNR1A) gene is linked to the risk of Alzheimer's disease in the elderly.

6 Jul 2018

Researchers find new way to convert skin cells into pluripotent stem cells

Our bodies consist of many different kinds of cells, each with their own role. The Japanese scientist Shinya Yamanaka had made earlier the discovery, earning the Nobel Prize in 2012, that cells from adult skin can be converted to cells typical of early embryos, so-called induced pluripotent stem cells.

6 Jul 2018

Researchers use precision genomics to search genetic mutations causing accelerated aging

Mayo Clinic researchers are using precision genomics to search for undiscovered, inheritable genetic mutations that cause accelerated aging. In a study recently published in Mayo Clinic Proceedings, researchers conducted a study assessing 17 patients with short telomere syndromes - rare conditions that result in premature DNA and cellular deterioration.

6 Jul 2018

Scientists develop novel method of producing pluripotent stem cells

Scientists have developed a modified CRISPR tool that can stimulate the de-differentiation of somatic cells into induced pluripotent stem cells,

6 Jul 2018

Gene therapy study shows promise for chronic kidney disease

A study has shown that a viral vector can deliver genetic material to damaged kidney cells, potentially providing a treatment that can slow or reverse chronic kidney disease.

6 Jul 2018

Pneumococcal genes predict course of disease

Pneumococcus is an important cause of pneumonia, sepsis and meningitis. This bacterium commonly resides in the nasal cavity.

6 Jul 2018

Researchers discover genetic marker associated with salt sensitivity of blood pressure

For the first time researchers have identified a genetic marker (GNAI2) that is associated with the risk of salt sensitivity in blood pressure regardless of age or gender.

5 Jul 2018

Candida Auris testing kit for use in hospital hygiene applications announced by Bruker

At the International Society for Human and Animal Mycology meeting, Bruker announces Fungiplex™ Candida Auris, a new research-use-only, real-time PCR assay and kit for the detection of Candida auris in hospital hygiene applications.

From Bruker Life Sciences Mass Spectrometry 4 Jul 2018

Natural selection may have influence on personalities, suggests study

For more than a century, scientists have understood that natural selection have profound effects on how an animal looks - Anolis lizards that spend more time on the ground, for example, might need longer legs for running, while species that remain in the trees usually have shorter legs better suited for climbing.

4 Jul 2018

Specific type of satellite RNA induces breast cancer, shows study

Only some of us have satellite TV in our homes, but all of us have satellite DNA in cells in our bodies. Working copies of satellite DNA are high in certain types of cancer, such as breast and ovarian.

4 Jul 2018

Potential oocyte-specific factors that can drive somatic cell reprogramming

The promise of generating truly pluripotent stem cells from terminally differentiated adult cell types continues to captivate scientists who envision great potential for therapeutic interventions.

4 Jul 2018

New computational strategy used to identify genes associated with childhood cancer

Using a new computational strategy, researchers at UT Southwestern Medical Center have identified 29 genetic changes that can contribute to rhabdomyosarcoma, an aggressive childhood cancer.

3 Jul 2018

Researchers develop switch that can control genome editing

Researchers have developed a biological switch that reliably triggers protein expression and enables the control of genome editing tools.

3 Jul 2018

New biomarker paves way for personalized bladder cancer treatments

Researchers have identified a potential new target for the treatment of a particularly aggressive form of bladder cancer, in the form of microRNA.

2 Jul 2018

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Screening a tiny section of DNA could help East Asian patients avoid severe reactions to some medications.

2 Jul 2018

Researchers discover gene that plays role in regulating body's immune response to infection

Australia's national science agency CSIRO has identified a new gene that plays a critical role in regulating the body's immune response to infection and disease.

2 Jul 2018

Timing may be key to evading destruction for bacteria facing antibiotics

For bacteria facing a dose of antibiotics, timing might be the key to evading destruction. In a series of experiments, Princeton researchers found that cells that repaired DNA damaged by antibiotics before resuming growth had a much better chance of surviving treatment.

30 Jun 2018

Individuals may react differently to environmental chemicals based upon genetic profile

Why do individuals respond differently to the same environment? Researchers from North Carolina State University and Oregon State University have pinpointed a genetic difference in zebrafish tied to differing responses to the same environmental chemical.

30 Jun 2018

Genomics

Widespread transfer of genes between species appears to be key driver of evolution

Single-cell RNA sequencing reveals how complex brain circuit works

Study finds common risk gene for both job-related exhaustion in shift workers and Alzheimer's

Researchers find new way to convert skin cells into pluripotent stem cells

Researchers use precision genomics to search genetic mutations causing accelerated aging

Scientists develop novel method of producing pluripotent stem cells

Gene therapy study shows promise for chronic kidney disease

Pneumococcal genes predict course of disease

Researchers discover genetic marker associated with salt sensitivity of blood pressure

Candida Auris testing kit for use in hospital hygiene applications announced by Bruker

Natural selection may have influence on personalities, suggests study

Specific type of satellite RNA induces breast cancer, shows study

Potential oocyte-specific factors that can drive somatic cell reprogramming

New computational strategy used to identify genes associated with childhood cancer

Researchers develop switch that can control genome editing

New biomarker paves way for personalized bladder cancer treatments

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Researchers discover gene that plays role in regulating body's immune response to infection

Timing may be key to evading destruction for bacteria facing antibiotics

Individuals may react differently to environmental chemicals based upon genetic profile

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Shaping the future of lab automation through AI and robotics

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