Genomics

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TGen project to develop standard operating procedures for single-cell RNA sequencing

The Translational Genomics Research Institute today announced grant support from the Chan Zuckerberg Initiative donor advised fund, an advised fund of the Silicon Valley Community Foundation, that will help revolutionize how researchers identify the genetic source of diseases and how best to treat each patient.

17 Oct 2017

Northwestern scientists discover 'wasabi receptor' for pain in flatworms

A Northwestern University research team has discovered how scalding heat and tissue injury activate an ancient "pain" receptor in simple animals. The findings could lead to new strategies for analgesic drug design for the treatment of humans.

17 Oct 2017

Genetic diversity plays major role in evolution of drug resistance

Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve. Scientists at the Wellcome Trust Sanger Institute and the Institute for Research on Cancer and Ageing of Nice in France, show that high genetic diversity can prime new mutations that cause drug resistance.

17 Oct 2017

Columbia scientists receive grant from CZI to construct atlas of cells in human spinal cord

Scientists at Columbia's Zuckerman Institute today received a grant from the Chan Zuckerberg Initiative donor advised fund, an advised fund of the Silicon Valley Community Foundation, to construct an atlas of gene activity of all cells in the human spinal cord.

17 Oct 2017

New model predicts how E. coli bacteria respond to temperature changes, genetic mutations

Researchers at the University of California San Diego have developed a genome-scale model that can accurately predict how E. coli bacteria respond to temperature changes and genetic mutations.

13 Oct 2017

Study helps understand basic mechanisms of mitochondrial DNA maintenance

Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. The study, published in PNAS earlier this week, was carried out in close collaboration with research groups from CBMSO in Madrid, Spain, and Umeå University in Sweden.

13 Oct 2017

MIT researchers develop new technique to screen for genes that protect against diseases

Using a modified version of the CRISPR genome-editing system, MIT researchers have developed a new way to screen for genes that protect against specific diseases.

12 Oct 2017

Whole genome sequencing could help better understand genetic abnormalities underlying autism

An analysis of the complete genomes of 2,064 people reveals that multiple genetic variations could contribute to autism. The work suggests that scanning whole genomes may one day be useful for clinical diagnostics.Autism has genetic roots, but most cases can't be explained by current genetic tests.

12 Oct 2017

TSRI scientists demonstrate repurposing of DNA to create new substances

DNA evolved to store genetic information, but in principle this special, chain-like molecule can also be adapted to make new materials. Chemists at The Scripps Research Institute have now published an important demonstration of this repurposing of DNA to create new substances with possible medical applications.

12 Oct 2017

New computer program identifies different cell types based on gene expression patterns

"How many different cell types are there in a human body? And how do these differences develop? Nobody really knows," says Professor Stein Aerts from KU Leuven and VIB, Belgium. But thanks to a new method developed by his team, that may be about to change.

10 Oct 2017

Effects of having familiar, good neighbors revealed in bird study

Birds who live next door to family members or to other birds they know well are physically healthier and age more slowly, according to new research from the University of East Anglia.

10 Oct 2017

Penn Medicine professor receives New Innovator Award from NIH

Hao Wu, PhD, an assistant professor of Genetics in the Perelman School of Medicine at the University of Pennsylvania has received a New Innovator Award from the National Institutes of Health. These awards provide each recipient $1.5 million over five years to pursue high-risk, high-reward investigations that could have implications for human health.

9 Oct 2017

New microcapsules represent promising vectors for application of genome-editing tools

Researchers from Tomsk Polytechnic University jointly with their colleagues from St. Petersburg, Hamburg and London have conducted a study in the course of which it was found out that polymer and hybrid silica-coated microcapsules are more efficient in genome-editing when applying CRISPR-Cas9 system.

6 Oct 2017

Forsyth researchers win $5.4 million NIH award to pursue research on oral microbes

A research team led by the Forsyth Institute today received a $5.4 million award from the National Institutes of Health to pursue revolutionary research of microbes living in the mouth and within the human body.

6 Oct 2017

Benefits of Biomarkers in Colorectal Cancer Treatment

Biomarkers fall into different categories: diagnostic biomarkers, are used to identify a disease; prognostic biomarkers, help clinicians to determine, for example, whether you're more likely to die or have problems with a disease; and there are some that can be used to inform treatment, to determine whether one therapy would be more successful than another.

2 Oct 2017

Deep Genomics receives $13 million investment to create new class of genetic drugs

Deep Genomics, the AI driven genetic medicine company, received a USD $13 million equity investment led by Khosla Ventures, one of the top venture capital firms. They are accompanied by early stage investment firm True Ventures.

28 Sep 2017

Chromatrap ChIP-Seq kits can deliver streamlined protocol from nanograms of starting material

Chromatrap has demonstrated that its unique solid state patented technology allows for ChIP-seq assays to be routinely performed from as little as 500 ng of chromatin.

From Chromatrap® - Porvair Sciences Ltd 28 Sep 2017

Cohen Veterans Bioscience partners with OCC to establish the Brain Commons database

Cohen Veterans Bioscience today announced its partnership with the Open Commons Consortium to establish the Brain Commons – a one-of-a-kind cloud-hosted site for combining Big Data that will be critical for the understanding of brain conditions.

28 Sep 2017

IMB researchers unveil mystery of aging process

Researchers at the Institute of Molecular Biology in Mainz have made a breakthrough in understanding the origin of the aging process. They have identified that genes belonging to a process called autophagy, which is one of the cells most critical survival processes, promote health and fitness in young worms but drive the process of aging later in life.

27 Sep 2017

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

My research uses budding yeast as a tool for synthetic biology, and also in chemical and functional genomic applications. We are interested in understanding molecular mechanisms and metabolic pathways of yeast for drug discovery.

From Tecan 27 Sep 2017

Genomics

TGen project to develop standard operating procedures for single-cell RNA sequencing

Northwestern scientists discover 'wasabi receptor' for pain in flatworms

Genetic diversity plays major role in evolution of drug resistance

Columbia scientists receive grant from CZI to construct atlas of cells in human spinal cord

New model predicts how E. coli bacteria respond to temperature changes, genetic mutations

Study helps understand basic mechanisms of mitochondrial DNA maintenance

MIT researchers develop new technique to screen for genes that protect against diseases

Whole genome sequencing could help better understand genetic abnormalities underlying autism

TSRI scientists demonstrate repurposing of DNA to create new substances

New computer program identifies different cell types based on gene expression patterns

Effects of having familiar, good neighbors revealed in bird study

Penn Medicine professor receives New Innovator Award from NIH

New microcapsules represent promising vectors for application of genome-editing tools

Forsyth researchers win $5.4 million NIH award to pursue research on oral microbes

Benefits of Biomarkers in Colorectal Cancer Treatment

Deep Genomics receives $13 million investment to create new class of genetic drugs

Chromatrap ChIP-Seq kits can deliver streamlined protocol from nanograms of starting material

Cohen Veterans Bioscience partners with OCC to establish the Brain Commons database

IMB researchers unveil mystery of aging process

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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