Histology & Microscopy

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Shapeshifting behavior of E. coli may offer clues to combat urinary tract infections

Urinary tract infections are both very common and potentially very dangerous. More than half of all Australian women will suffer from a UTI in their lifetime, and nearly one in three women will have an infection requiring treatment with antibiotics before the age of 24.

28 Jun 2022

Bacterium discovery helps to solve the puzzle of what factors limit cell size

On sunken leaves in the waters of a Caribbean mangrove swamp, researchers discovered a bacterium that challenges the prevailing view of bacterial cell size; counter to the notion that microbes are only visible with a microscope, this one – named Thiomargarita magnifica – is larger than all other known giant bacteria by ~50-fold, and can be seen by the naked eye, the study's authors say.

23 Jun 2022

Study unveils a precise model for the stinging organelle of starlet sea anemone

Summertime beachgoers are all too familiar with the painful reality of a jellyfish sting. But how do the stinging cells of jellyfish and their coral and sea anemone cousins actually work? New research from the Stowers Institute for Medical Research unveils a precise operational model for the stinging organelle of the starlet sea anemone, Nematostella vectensis.

23 Jun 2022

Bruker introduces enhanced 3D holographic stimulation for optogenetics on its Ultima 2Pplus multiphoton microscope

Bruker Corporation today announced the release of the NeuraLight 3D Ultra™ module to support advanced neuroscience and optogenetics research applications on Bruker’s Ultima multiphoton microscopes.

From Bruker Nano Surfaces and Metrology 16 Jun 2022

New project seeks to develop a microscopy system for making drug interactions in the liver visible

Bielefeld University is coordinating a new EU-research project that seeks to produce microscopic liver tissue cultures that can survive for 14 days, while also using imaging methods to investigate how liver cells react to combinations of different medications.

14 Jun 2022

Deciphering the structure of nuclear pore complex piece by piece

Whatever you are doing, whether it is driving a car, going for a jog, or even at your laziest, eating chips and watching TV on the couch, there is an entire suite of molecular machinery inside each of your cells hard at work.

10 Jun 2022

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house.

9 Jun 2022

Advanced microscopy techniques offer detailed insight into inner workings of cells' powerhouses

Using advanced microscopy techniques, researchers at Karolinska Institutet and Stockholm University in Sweden have visualized in unprecedented detail the machinery that the cells' powerhouses, the mitochondria, use to form their proteins.

8 Jun 2022

Discovery of small protein’s structure could lead to new therapies for neurological disorders

Scientists have, for the first time, revealed at the atomic level the structure of a protein that carries one of the body's most important neurotransmitters into neurons.

8 Jun 2022

Color-changing mouse model aids in better visualization of internal physiology

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have developed a process to change the color of a mouse's tissue in imaging to better visualize its internal physiology.

6 Jun 2022

Steady-state DNA motion allows cells to conduct housekeeping tasks under similar nuclear environments

Researchers in Japan have discovered that the local DNA motion inside of human cells remains steady throughout interphase, where the cell grows and replicates its DNA for cell division.

3 Jun 2022

Using diffusion-weighted MRI to visualize brain inflammation in vivo for the first time

Research of the laboratories led by Dr. Silvia de Santis and Dr. Santiago Canals, both from the Institute of Neurosciences UMH-CSIC (Alicante, Spain), has made it possible to visualize for the first time and in great detail brain inflammation using diffusion-weighted Magnetic Resonance Imaging.

27 May 2022

Research offers entirely new ways to visualize cell membranes

Research from the lab of Matthew Lew at Washington University in St. Louis offers entirely new ways to see the very small.

27 May 2022

Researchers focus on how bacterial cells adapt and resist antibiotics

Treatment of severe infections caused by pathogenic bacteria relies on ‘last resort’ antibiotics, but rising resistance by ‘superbugs’ to most clinically approved drugs leaves patients exposed to possible fatalities.

26 May 2022

UCLA researchers discover key molecular mechanism behind memory linking

Our brains rarely record single memories-;instead, they store memories into groups so that the recollection of one significant memory triggers the recall of others connected by time.

25 May 2022

Cryogenic electron microscopy used to determine the structure of fungal ribosome

Most people carry the fungus Candida albicans on their bodies, without this causing many problems. However, a systemic infection with this fungus is dangerous and difficult to treat.

25 May 2022

New imaging approach helps scientists build a complete picture of brain networks

Researchers at the Francis Crick Institute have developed an imaging technique to capture information about the structure and function of brain tissue at subcellular level – a few billionth of a metre, while also capturing information about the surrounding environment.

25 May 2022

Histology & Microscopy

Shapeshifting behavior of E. coli may offer clues to combat urinary tract infections

Bacterium discovery helps to solve the puzzle of what factors limit cell size

Study unveils a precise model for the stinging organelle of starlet sea anemone

Bruker introduces enhanced 3D holographic stimulation for optogenetics on its Ultima 2Pplus multiphoton microscope

New project seeks to develop a microscopy system for making drug interactions in the liver visible

Deciphering the structure of nuclear pore complex piece by piece

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

Advanced microscopy techniques offer detailed insight into inner workings of cells' powerhouses

Discovery of small protein’s structure could lead to new therapies for neurological disorders

Color-changing mouse model aids in better visualization of internal physiology

Steady-state DNA motion allows cells to conduct housekeeping tasks under similar nuclear environments

Using diffusion-weighted MRI to visualize brain inflammation in vivo for the first time

Research offers entirely new ways to visualize cell membranes

Researchers focus on how bacterial cells adapt and resist antibiotics

UCLA researchers discover key molecular mechanism behind memory linking

Cryogenic electron microscopy used to determine the structure of fungal ribosome

New imaging approach helps scientists build a complete picture of brain networks

UAB researchers track the behavior of microplastics inside a living organism

Novel AI algorithm developed for assessing digital pathology data

Researchers combine two emerging imaging technologies to better view biomolecules

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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