Histology & Microscopy

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EPFL researchers achieve near-perfect control of individual molecules for improving sensing precision

Aleksandra Radenovic, head of the Laboratory of Nanoscale Biology in the School of Engineering, has worked for years to improve nanopore technology, which involves passing a molecule like DNA through a tiny pore in a membrane to measure an ionic current.

19 Jun 2023

Detailed 3D images of the synapse offer precise geometry of interactions between individual cells

Scientists have created one of the most detailed 3D images of the synapse, the important juncture where neurons communicate with each other through an exchange of chemical signals. These nanometer scale models will help scientists better understand and study neurodegenerative diseases such as Huntington's disease and schizophrenia.

15 Jun 2023

Researchers create a diagnostic test to identify functional sperm in infertile men

In a recent study, researchers created a diagnostic test to identify functional sperm in infertile men that could change the treatment of male infertility and assisted reproductive technology.

14 Jun 2023

Algorithm from a video game provides insights into the behavior of molecules within live brain cells

University of Queensland researchers have used an algorithm from a video game to gain insights into the behavior of molecules within live brain cells.

14 Jun 2023

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals - from fuels to fabrics and drugs - beyond the normal repertoire of microbes.

13 Jun 2023

UCL researchers produce first image of the structures that power human cilia

The first image of the structures that power human cilia – the tiny, hairlike projections that line our airways – has been produced by a team involving UCL researchers and could lead to much-needed treatments for people with rare cilial diseases.

13 Jun 2023

Scientists determine the atomic-level structure of a zinc-transporter protein

Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have determined the atomic-level structure of a zinc-transporter protein, a molecular machine that regulates levels of this crucial trace metal micronutrient inside cells.

9 Jun 2023

Cryo-EM reveals key atomic structures of the ends of actin filament

Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing "barbed" and shrinking "pointed" ends.

8 Jun 2023

Study uncovers novel mechanisms underlying plant immunity against major root disease

Researchers led by CHEN Yuhang and ZHOU Jianmin from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have shown how plants resist clubroot, a major root disease that threatens the productivity of Brassica crops such as rape.

8 Jun 2023

Teaming up with the patient’s immune system to combat cancer

The fact that our immune systems capture and destroy nanoparticles and the drugs they carry has been a problem in the field of nanomedicine for some time. But, in the fight against cancer, researchers are now attempting to exploit this problem to their advantage.

8 Jun 2023

New process can help to design drugs with fewer or no side effects

Have you ever wondered how drugs reach their targets and achieve their function within our bodies? If a drug molecule or a ligand is a message, an inbox is typically a receptor in the cell membrane.

7 Jun 2023

Innovative platform helps observe the fine details of luminal flow around the villi

Science is well aware of the important role that gut bacteria and their interactions with the gastrointestinal tract play in our overall health.

30 May 2023

New method to study the ultra-fast movements of proteins

Proteins are biological molecules that perform almost all biochemical tasks in all forms of life. In doing so, the tiny structures perform ultra-fast movements.

30 May 2023

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Our cells are crisscrossed by a system of membrane tubes and pockets called the endoplasmic reticulum (ER). It is crucial for the production of biomolecules and is continuously built up and degraded.

26 May 2023

Fast and accurate automatic neuron reconstruction using 3D images

Dr. Shuiwang Ji, a professor in the Department of Computer Science and Engineering at Texas A&M University, is part of a collaborative research community that recently had its paper titled "BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets" published in the April issue of the journal Nature Methods.

26 May 2023

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

In this behind-the-scenes interview, we speak to Dr. Sinead Knight, chair of SLAS Europe 2023, about this years programme, highlighting the key topics and speakers.

From Society for Laboratory Automation and Screening (SLAS) 25 May 2023

$Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride$

Histology & Microscopy

EPFL researchers achieve near-perfect control of individual molecules for improving sensing precision

Detailed 3D images of the synapse offer precise geometry of interactions between individual cells

Researchers create a diagnostic test to identify functional sperm in infertile men

Algorithm from a video game provides insights into the behavior of molecules within live brain cells

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

UCL researchers produce first image of the structures that power human cilia

Scientists determine the atomic-level structure of a zinc-transporter protein

Cryo-EM reveals key atomic structures of the ends of actin filament

Study uncovers novel mechanisms underlying plant immunity against major root disease

Teaming up with the patient’s immune system to combat cancer

New process can help to design drugs with fewer or no side effects

Innovative platform helps observe the fine details of luminal flow around the villi

New method to study the ultra-fast movements of proteins

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Fast and accurate automatic neuron reconstruction using 3D images

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride

Understanding the cause for suboptimal germinal center response in aged mice

Novel tool paves the way for automated identification and localization of proteins in cells

Researchers create a 3D model to better understand bacteria movement

Reimagining light scattering for biotherapeutics

Empowering genomics research with cloud-based innovation

Quality, Patient Safety and Innovation Manager at Elsevier

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