Histology & Microscopy

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The Acoustics of the Brain: Random-access 3D Microscopy in Neuroscience

Máté Marosi and Zsolt Iván discuss the use of acousto-optic microscopes to study neural networks in the brain, from cell bodies to dendrites, to tiny spines.

From Femtonics Ltd. 17 Dec 2019

Super-resolution localization photoacoustic microscopy can find blocked or burst blood vessels

200 years ago, a doctor from France used a stethoscope for the first time and countless efforts to observe human body have been made since then. Up to now, the best tool that provides anatomical, functional, and molecular information of human and animal is the photoacoustic microscopy.

16 Dec 2019

75-year old blood-stained microscope slide reveals historical spread of malaria

DNA from 75-year old eradicated European malaria parasites uncovers the historical spread of one of the two most common forms of the disease, Plasmodium vivax, from Europe to the Americas during the colonial period, finds a new study co-led by UCL.

2 Dec 2019

Air pollution associated with increased risk of deaths in Canada

Air pollution - even at levels below national and international air quality guidelines - is associated with an increased risk of deaths in Canada, according to new UBC research.

25 Nov 2019

Doughnut-shaped circles of ecDNA provide tumor cells with a malignant twist

Deoxyribonucleic acid or DNA encodes information, not only in its sequence but also in its shape.

21 Nov 2019

Label-free multimodal imaging platform enables non-invasive study of cell cultures

Most analytical methods in biology require invasive procedures to analyze samples, which leads to irreversible changes or even their destruction.

20 Nov 2019

Researchers decode molecular structure of cytochrome bd oxidase from E. coli

Both humans and many other creatures need oxygen for survival. In the conversion of nutrients into energy, the oxygen is converted to water, for which the enzyme oxidase is responsible. It represents the last step of the so-called respiratory chain.

14 Nov 2019

Study unravels how insulin interacts with its receptor

Since the discovery of insulin nearly 100 years ago, scientists have explored how it interacts with its receptor with the goal of improving the ability of therapeutic insulins to mimic the way insulin works in the body.

14 Nov 2019

Thermo Scientific Aquilos 2 Cryo-FIB reduces sample preparation time

Thermo Fisher Scientific today announced the Thermo Scientific Aquilos 2 Cryo-FIB, a DualBeam system dedicated to the preparation of thin, electron-transparent samples from biological specimens.

From Thermo Fisher Scientific – Electron Microscopy Solutions 11 Nov 2019

New imaging methods provide unprecedented close-up view of cilia linked to blindness

A new study published today by researchers from Baylor College of Medicine and UT Health's McGovern Medical School in the Proceedings of the National Academy of Sciences reveals an unprecedented close-up view of cilia linked to blindness.

5 Nov 2019

Discovery of 'cellular bike couriers' could shed light on disease spreading mechanisms

A previously unknown component of our cells that delivers proteins like a bike courier in heavy traffic could shed light on the mechanisms that allow cells to spread in diseases such as cancer.

31 Oct 2019

Scientists solve first structure of human cotransporter protein KCC1

In work that could someday improve treatments for epilepsy, UT Southwestern scientists have published the first three-dimensional structure of a member of a large family of human proteins that carry charged particles – ions – across the cell membrane.

29 Oct 2019

Shape of lung tissue fibers influences respiratory elasticity

Take a deep breath. Now exhale. Congratulations! You've just done something completely ordinary, yet so mysterious that scientists still don't know everything about it.

29 Oct 2019

Researchers use 3D electron microscopy to unravel dense networks in the cerebral cortex

Unlike any other organ, our brains contain extremely densely packed networks of membranous cables that are used by our about 86 billion nerve cells for communication amongst each other.

24 Oct 2019

Discovery about DNA-reeling bacteria can help inform strategies to stop bacterial infection

A new study from Indiana University has revealed a previously unknown role a protein plays in helping bacteria reel in DNA in their environment -- like a fisherman pulling up a catch from the ocean.

21 Oct 2019

SciLifeLab and AstraZeneca establish cryo-EM collaboration to advance biomedicine

The study published in Science Advances reveals the mechanism by which the receptor tyrosine kinase RET can increase neuronal survival in degenerative diseases. To understand the mechanism of this signaling complex, the researchers solved the cryo-EM structure of its extracellular region, employing a new approach for data collection.

21 Oct 2019

Salk scientists receive NIH funding to map brain circuitry for movement

A team of Salk scientists led by Professor Martyn Goulding has been awarded $14.3 million over five years by the National Institutes of Health to create a high-resolution atlas of how the mouse brain generates and controls skilled forelimb movements, such as reaching and grasping.

18 Oct 2019

Driving Adoption of Digital Pathology with Image Search

Driving adoption of digital pathology through the Scan Image Search from Huron Digital Pathology. Patrick Myles talks to the Dell Healthcare PowerChat Podcast.

From Huron Digital Pathology 1 Oct 2019

High-speed imaging technology reveals previously unseen details of living creatures

The Columbia team behind the revolutionary 3D SCAPE microscope announces today a new version of this high-speed imaging technology.

27 Sep 2019

New technique can rapidly image synaptic proteins at high resolution

Our brains contain millions of synapses -- the connections that transmit messages from neuron to neuron. Within these synapses are hundreds of different proteins, and dysfunction of these proteins can lead to conditions such as schizophrenia and autism.

26 Sep 2019