Histology & Microscopy

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Researchers map and activate bacterial 'immune defense system'

With the aid of highly advanced microscopes and synchrotron sources, researchers from the University of Copenhagen have gained seminal insight into how bacteria function as defense mechanisms against attacks from other bacteria and viruses.

24 Sep 2019

Label-free laser microscopy technique accurately detects ovarian metastatic cancer

Women undergoing treatment for ovarian cancer are checked for tumor cells that may have spread to surrounding tissues, but current technologies miss very small metastatic areas. Now a laser microscopy technique is able to identify these regions with great accuracy.

17 Sep 2019

Accelerating Nanobody Production using Polyclonal Anti-VHH Antibodies

In this interview, Dr. Dave Fancy, CEO of Jackson ImmunoResearch explains how anti-VHH antibodies can be used to produce nanobodies and VHH libraries.

From Jackson ImmunoResearch Laboratories, Inc. 12 Sep 2019

HORIBA’s Yumizen hematology analyzers minimize microscopy slide reviews, improve diagnosis

HORIBA UK Ltd, Medical announces the publication of scientific studies which demonstrate the excellent performance of its new HELO high throughput fully automated haematology platform on body fluid and pathological samples.

From HORIBA Scientific UK 11 Sep 2019

Innovative method could improve understanding of many processes in the body at molecular level

Cells are the basic building blocks of life - and, as such, they have been the object of intense study since the invention of the optical microscope in the 17th century.

7 Sep 2019

Sensing temperature inside cells using a fluorescent nano-thermometer

How do you know a cell has a fever? Take its temperature.

23 Aug 2019

Using principles of mechanics and physics to identify state of individual cells

Researchers at the NYU Tandon School of Engineering have discovered a new way to identify the state of individual cells by bringing principles of mechanical engineering and physics to bear on processes that are now well understood at the macro level, but not yet at the cellular level: how stressors such as injury and disease force an organism into a new level of equilibrium -- a biological process of finding a "new normal" called allostasis.

20 Aug 2019

Olympus launches first Global Image of the Year Life Science Light Microscopy Award

Inspired by the beauty and breadth of images submitted for the 2018 Image of the Year Life Science Light Microscopy Award held in Europe, Olympus has launched its first Global Image of the Year Life Science Light Microscopy Award, recognizing the best in life science imaging worldwide.

From Evident Corporation - Life Sciences 8 Aug 2019

Japanese scientists develop new method to construct 3D models from 2D images

Japanese scientists report in Pattern Recognition a new method to construct 3D models from 2D images. The approach, which involves non-rigid registration with a blending of rigid transforms, overcomes several of the limitations in current methods.

6 Aug 2019

Thermo Fisher Scientific unveils new Krios solution at Microscopy and Microanalysis 2019

Today at Microscopy and Microanalysis 2019, Thermo Fisher Scientific unveiled a new Krios solution designed to break down the barriers to cryo-EM adoption through improved ease-of-use, faster results and the most compact 300kV cryo-EM microscope design on the market.

From Thermo Fisher Scientific – Electron Microscopy Solutions 6 Aug 2019

Automating cryo-EM sample preparation

SPT Labtech has today announced the introduction of chameleon, an industry-enabling sample-preparation system for cryo-EM.

From SPT Labtech 6 Aug 2019

Researchers explore how HIV spreads in 3D tissue-like environments

The spread of pathogens like the human immunodeficiency virus (HIV) is often studied in a test tube, i.e. in two-dimensional cell cultures, even though it hardly reflects the much more complex conditions in the human body.

25 Jul 2019

New Multiplex mode for ZEISS Airyscan 2 delivers images with superresolution in less time

The new Multiplex mode for ZEISS Airyscan 2 delivers more information in less time. Smart illumination and detection schemes allow parallel pixel acquisition for fast and gentle confocal microscopy.

From Carl Zeiss Microscopy GmbH 25 Jul 2019

High-resolution images offer clues to improve design of anti-nausea drugs

A new study using a special type of electron microscope using samples cooled to extremely cold temperatures provides critical information for drug developers seeking to reduce nausea and vomiting side effects of cancer treatments.

23 Jul 2019

Researchers identify toxin responsible for Legionella growth

A team of scientists led by EMBL group leader Sagar Bhogaraju and Ivan Dikic of Goethe University, Frankfurt, discovered that the toxin SidJ in Legionella bacteria enforces a unique modification on human proteins and helps legionella grow inside human cells.

22 Jul 2019

IT Faces the Digital Pathology Data Tsunami

Digital pathology is the viewing, analyzing, and managing of digitalized pathology slides with computer technology.

From Huron Digital Pathology 17 Jul 2019

Raman Spectroscopy as a Universal Analytical Technique for Bodily Fluids

Professor Igor K. Lednev explains why Raman spectroscopy could replace biochemical tests for the analysis of bodily fluids in forensic science.

From Pittcon 16 Jul 2019

Tomocube HT microscope enables label-free quantification of cellular lipid content

In a breakthrough for research fields as diverse as diabetes, atherosclerosis and biofuels, the mass, concentration, volume, and surface area of individual lipid droplets have been measured in live, unstained cells for the first time using a Tomocube Holotomography microscope.

From Tomocube Inc. 12 Jul 2019

Researchers capture high-resolution, 3D images of gene-editing enzymes

For the first time, scientists have captured high-resolution, three-dimensional images of an enzyme in the process of precisely cutting DNA strands.

9 Jul 2019

Cutting-edge electron microscopy reveals first structures of a lipid-flippase

Using cutting-edge electron microscopy, researchers from Aarhus University have determined the first structures of a lipid-flippase.

29 Jun 2019