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Study shows outcomes of CAR T-cell therapy when used as standard of care for lymphoma

Chimeric antigen receptor T-cell therapy, or CAR T, was named the 2017 Advance of the Year by the American Society of Clinical Oncology. The FDA approved two CAR T products last year for treatment of adult large B-cell lymphoma based on the exceptional patient outcomes seen in clinical trials.

3 Dec 2018

UK scientists find new way to identify patients with aggressive lymphoma

UK scientists have found a new way to identify people with the most aggressive types of lymphoma who are less likely to respond to standard drugs.

3 Dec 2018

Very low calorie diet for type 2 diabetes to be prescribed

General Practitioners in England would soon prescribe a very low calorie diet (VLCD) for patients with type 2 diabetes in England as part of an attempt to reverse the increasingly growing numbers of the disease.

3 Dec 2018

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

A gene mutation that is believed to have safeguarded some people in 14th century Europe from the bubonic plague today may be protecting HIV patients co-infected with hepatitis C from potentially fatal liver scarring, says a University of Cincinnati College of Medicine physician-scientist.

3 Dec 2018

Tailored lifestyle recommendations during colorectal cancer screening promote healthy behaviors

A program that provided individually tailored lifestyle recommendations for patients undergoing screening for colorectal cancer helped encourage healthy behavior, according to results published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

3 Dec 2018

Researchers uncover genes that lead to excessive tau in dementia

Researchers have identified two major groups of genes involved in the mutations that lead to excess production of tau, a protein involved in dementia.

3 Dec 2018

Full marathons may increase concentrations of biomarkers of cardiac strain

Full marathons may significantly raise concentrations of several biomarkers of strain on the heart, according to new research in Circulation, Journal of the American Heart Association.

3 Dec 2018

Study: 51% of patients alive two years after receiving CAR-T therapy for diffuse large B-cell lymphoma

A follow-up analysis of patients enrolled in a Phase I/II multi-center trial for diffuse large B-cell lymphoma reported 51 percent of patients receiving an anti-CD19 chimeric antigen receptor (CAR T) called axi-cel were still alive two years post-treatment.

3 Dec 2018

Cleveland Clinic expert develops personalized prediction model for Myelodysplastic Syndromes

At the American Society of Hematology Annual Meeting, Cleveland Clinic medical hematologist and oncologist Aziz Nazha, M.D., will present results of a personalized prediction model that surpassed current prediction models for Myelodysplastic Syndromes.

3 Dec 2018

People with epilepsy who live in high-crime neighborhoods experience more seizures

People with epilepsy living in high crime neighborhoods in Chicago had three times as many seizures as those living in neighborhoods with lower crime rates according to new research from the University of Illinois at Chicago presented at the American Epilepsy Society 2018 conference in New Orleans.

3 Dec 2018

CAR T therapy can lead to long-lasting remissions in patients with r/r diffuse large B-cell lymphoma

In an update to a global clinical trial stretching from Philadelphia to four continents, the chimeric antigen receptor (CAR) T cell therapy Kymriah (tisagenlecleucel, formerly CTL019) led to long-lasting remissions in patients with relapsed/refractory (r/r) diffuse large B-cell lymphoma (DLBCL).

3 Dec 2018

Study: Patients with cancer have worse outcomes after heart procedure

Research led by Keele University suggests that patients with cancer who undergo a common heart procedure have worse short-term clinical outcomes compared to non-cancer patients, in the largest study undertaken to date.

30 Nov 2018

Scientists alleviate schizophrenic symptoms in mice

Despite extensive research efforts, schizophrenia remains one of the least understood brain disorders. One promising area of research is in receptors on the surfaces of brain cells that help sense growth factors.

30 Nov 2018

Link found between light pollution and insomnia in older adults

A new study is the first population-based investigation to report a significant association between artificial, outdoor light exposure at night and insomnia, as indicated by older adults' use of hypnotic drugs.

30 Nov 2018

Study explores whether patients from poorest neighborhoods experience longer total ambulance times

Patients from the poorest neighborhoods who had cardiac arrest had longer total ambulance times than those from the wealthiest neighborhoods.

30 Nov 2018

Chronic kidney disease rates are increasing faster than other noninfectious diseases

Advances in treating cancer, heart disease and other major health conditions in recent decades have extended life spans for millions of people.

30 Nov 2018

Night owls may have increased risk of ill health, study finds

Night owls may have a higher risk of suffering from heart disease and type 2 diabetes than early risers.

30 Nov 2018

Researchers identify potential nutritional alternative for people with fish allergy

Fish allergy is one of the most dangerous food allergies, as it is often associated with potentially life-threatening symptoms such as anaphylactic shock.

30 Nov 2018

$Many diseases increase risk of post-operative complications after hip fracture surgery$

Many diseases increase risk of post-operative complications after hip fracture surgery

Parkinson's disease, osteoarthritis, rheumatic diseases, alcoholism and mental health disorders increase the risk of surgical complications after a hip fracture surgery, a new Finnish study analyzing nationwide registers finds.

30 Nov 2018

Researchers elucidate central mechanisms of salt-induced hypertension through sympathetic activation

Hypertension is a major risk factor for cardiovascular disease worldwide, and approximately 40% (1 billion) of adults aged 25 and above have been diagnosed with hypertension. A positive correlation between salt intake and blood pressure has long been postulated.

30 Nov 2018

Medical Condition News

Study shows outcomes of CAR T-cell therapy when used as standard of care for lymphoma

UK scientists find new way to identify patients with aggressive lymphoma

Very low calorie diet for type 2 diabetes to be prescribed

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

Tailored lifestyle recommendations during colorectal cancer screening promote healthy behaviors

Researchers uncover genes that lead to excessive tau in dementia

Full marathons may increase concentrations of biomarkers of cardiac strain

Study: 51% of patients alive two years after receiving CAR-T therapy for diffuse large B-cell lymphoma

Cleveland Clinic expert develops personalized prediction model for Myelodysplastic Syndromes

People with epilepsy who live in high-crime neighborhoods experience more seizures

CAR T therapy can lead to long-lasting remissions in patients with r/r diffuse large B-cell lymphoma

Study: Patients with cancer have worse outcomes after heart procedure

Scientists alleviate schizophrenic symptoms in mice

Link found between light pollution and insomnia in older adults

Study explores whether patients from poorest neighborhoods experience longer total ambulance times

Chronic kidney disease rates are increasing faster than other noninfectious diseases

Night owls may have increased risk of ill health, study finds

Researchers identify potential nutritional alternative for people with fish allergy

Many diseases increase risk of post-operative complications after hip fracture surgery

Researchers elucidate central mechanisms of salt-induced hypertension through sympathetic activation

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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