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Researchers identify novel mutation in amyloid diseases

Researchers have identified a one-of-a kind mutation in the DNA of a patient who died of transthyretin (TTR) amyloidosis, a progressive condition characterized by the buildup of abnormal deposits of a misfolded protein called amyloid in the body's organs and tissues.

26 Jun 2018

Study suggests new approach for treating alcohol use disorder

Activation of a receptor with no known function in the brain reduces excessive alcohol use and the pain of withdrawal, according to preclinical research in male rats. The study, published in eNeuro, suggests a new approach towards the treatment of alcohol use disorder.

26 Jun 2018

Canadian researchers uncover new molecular mechanism to stop proliferation of cancer cells

Canadian researchers have discovered a new and direct molecular mechanism to stop cancer cells from proliferating. In the prestigious journal Nature Cell Biology, scientists from Université de Montréal show that a disruption of a fine balance in the composition of ribosomes (huge molecules that translate the genetic code into proteins) results in a shutdown of cancer cell proliferation, triggering a process called senescence.

26 Jun 2018

Unlocked and loaded: Families confront dementia and guns

With a bullet in her gut, her voice choked with pain, Dee Hill pleaded with the 911 dispatcher for help.

25 Jun 2018

FDA approves new marijuana-based drug to treat rare and severe forms of epilepsy

The U.S. Food and Drug Administration today approved Epidiolex (cannabidiol) oral solution for the treatment of seizures associated with two rare and severe forms of epilepsy, Lennox-Gastaut syndrome and Dravet syndrome, in patients two years of age and older.

25 Jun 2018

CRISPR technique reduces repetitive behavior in fragile X syndrome mouse models

Scientists have used CRISPR-Cas9 gene editing to lessen some autism symptoms in mice with a form of fragile X syndrome, the most common known single-gene cause of autism spectrum disorder.

25 Jun 2018

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

AbbVie , a research-based global biopharmaceutical company, and Calibr, a nonprofit drug discovery division of Scripps Research, today announced a collaboration to develop T-cell therapies aimed primarily at cancer, including solid tumors.

25 Jun 2018

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

A tumor's goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate.

25 Jun 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

Chemical compounds produced by gut bacteria could help spot early stages of liver disease

Chemical compounds produced by the bacteria in our gut could be used to spot the early stages of liver disease, according to new research.

25 Jun 2018

Researchers work on new treatment that could improve lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University are working on a treatment that holds great promise for improving the lives of cystic fibrosis patients.

25 Jun 2018

New discovery suggests potential target for treating cancers and other diseases

When cells grow and divide to ensure a biological function - such as a properly working organ - DNA must be unwound from its typical tightly packed form and copied into RNA to create proteins.

25 Jun 2018

Eye could be a surrogate for brain degeneration like AD

Researchers from Queen's University Belfast have shown for the first time that the eye could be a surrogate for brain degeneration like Alzheimer's disease (AD).

25 Jun 2018

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Cedars-Sinai has launched an initiative to accelerate the development of novel drugs, devices and therapies aimed at improving treatments for patients with gastrointestinal and metabolic diseases.

25 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

New tests accurately detect heart disease and adverse cardiac events in diabetic patients

Prevencio, Inc. today announces data which indicates its HART CAD and HART CVE tests accurately diagnose Coronary Artery Disease and risk for Major Adverse Cardiac Events in Diabetic Mellitus patients.

25 Jun 2018

Study links molecular changes in the brain to key behaviors in addiction

Changes in a brain signaling system contribute to the development of alcohol addiction-like behaviors in rats, according to a new study led by researchers at Linköping University, Sweden.

25 Jun 2018

Lund researchers develop fluorescent variant of a molecule that inhibits cancer stem cells

A team of researchers at Lund University in Sweden has developed a fluorescent variant of a molecule that inhibits cancer stem cells.

25 Jun 2018

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Pancreatic cancer is lethal in about 95% of cases mostly due to failure of first-line therapy gemcitabine. AntiCancer Inc.'s oral methioninase (AC 00619), which is in late pre-clinical development as an anti-cancer as well as an anti-aging drug, has now been shown to overcome gemcitabine resistance in mouse models of human pancreatic cancer, including AntiCancer's patient-derived orthotopic xenograft mouse models.

25 Jun 2018

Scientists identify immune cells that remove degenerating neurons after brain injury

Researchers have identified the immune cells that are responsible for clearing dead and dying nerve cells following a brain injury.

25 Jun 2018

Medical Condition News

Researchers identify novel mutation in amyloid diseases

Study suggests new approach for treating alcohol use disorder

Canadian researchers uncover new molecular mechanism to stop proliferation of cancer cells

Unlocked and loaded: Families confront dementia and guns

FDA approves new marijuana-based drug to treat rare and severe forms of epilepsy

CRISPR technique reduces repetitive behavior in fragile X syndrome mouse models

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

Researchers discover immune profile for effective cancer immunotherapy

Chemical compounds produced by gut bacteria could help spot early stages of liver disease

Researchers work on new treatment that could improve lives of cystic fibrosis patients

New discovery suggests potential target for treating cancers and other diseases

Eye could be a surrogate for brain degeneration like AD

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

New tests accurately detect heart disease and adverse cardiac events in diabetic patients

Study links molecular changes in the brain to key behaviors in addiction

Lund researchers develop fluorescent variant of a molecule that inhibits cancer stem cells

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Scientists identify immune cells that remove degenerating neurons after brain injury

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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