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Scientists suggest need for new approach to confront side effects of common anti-cancer therapy

Results of a new study by neuroscientists at the University of Massachusetts Amherst and the University of Toronto suggest that a new treatment approach is needed - and how this may be possible - to address adverse effects of aromatase inhibitors, drugs commonly prescribed to both men and women to prevent recurrence of estrogen-positive breast cancer.

27 Dec 2018

Neuronal cell death in Alzheimer's disease may actually not be a bad thing, shows study

For the first time, scientists at the Champalimaud Centre for the Unknown, in Lisbon, Portugal, have shown that neuronal cell death in Alzheimer's disease may actually not be a bad thing - on the contrary, it may be the result of a cell quality control mechanism trying to protect the brain from the accumulation of malfunctioning neurons.

27 Dec 2018

Study finds risk factors linked to REM sleep behavior disorder

Taking antidepressants for depression, having post-traumatic stress disorder or anxiety diagnosed by a doctor are risk factors for a disruptive and sometimes violent sleep disorder called rapid eye movement (REM) sleep behavior disorder, according to a study published in the December 26, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

27 Dec 2018

Breast cancer drugs could tackle lung cancers resistant to targeted therapies

A class of drugs used to treat certain breast cancers could help to tackle lung cancers that have become resistant to targeted therapies, suggests a new study in mice from the Francis Crick Institute and the Institute of Cancer Research.

27 Dec 2018

NIPER researcher presents a review on autophagy in neuronal cells

Autophagy is a cellular degradation process that can cause the death of a cell in certain conditions. Autophagy is necessary to maintain cellular homeostasis by clearing out damaged cellular organelles and proteins through certain pathways.

27 Dec 2018

Genetic testing can help personalize diagnosis and treatment of kidney disease, study shows

A new study has found that genes cause about 1 in 10 cases of chronic kidney disease in adults, and identifying the responsible gene has a direct impact on treatment for most of these patients.

26 Dec 2018

Yale researchers use arthritis medication to treat patient with disfiguring sarcoidosis

An all-Yale team of researchers successfully treated a patient with disfiguring sarcoidosis, a chronic disease that can affect multiple organs, with a drug approved for rheumatoid arthritis.

26 Dec 2018

Using untargeted metabolomics to find biomarkers and therapeutic targets for CVD

Cardiovascular diseases are proven to be the leading cause of deaths throughout the world. If statistics are reviewed, almost four out of five deaths are due to myocardial infarction or stroke. Efforts to prevent CVD have little effect on the decrease of the number of CVD related deaths despite many medical advances.

26 Dec 2018

Study investigates role of miRNAs in anesthetic-induced myocardial conditioning

Many studies have shown that the mechanism of drug-induced myocardial conditioning is enzyme-mediated through messenger RNA and miRNA regulation. In this study Orriach et al. investigated the role that miRNAs play in the cardio-protective effect of halogenated anesthetics, which are widely used in cardiac surgery.

26 Dec 2018

New method of cancer stem cells activation to destroy tumors

This risky method of anti-cancer therapy was suggested by scientists of Far Eastern Federal University (FEFU). Their review of mechanisms for molecular activation of stem cells of gliomas (most widely-spread brain tumors) was approved for publishing in the Frontiers in Cellular Neuroscience journal.

26 Dec 2018

Lupin partners with Abbvie to develop and commercialize new targeted oncology treatments

Pharma major Lupin Limited and global biopharmaceutical company AbbVie Inc., today announced that AbbVie has licensed Lupin's MALT1 (Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1) inhibitor program.

25 Dec 2018

New mechanism may explain neurons shrinking in Huntington's disease

A hallmark of neurodegenerative diseases like Huntington's is the progressive death of nerve cells in the brain. The cells don't die quickly, though. They first start to disconnect from each other because their neurites -- long finger-like extensions that make connections all through the brain -- become smaller.

25 Dec 2018

Simple tests in GP surgeries could increase diagnosis rate of liver disease

Research carried out by scientists at the University of Southampton has shown that simple tests in GP surgeries could potentially double the diagnosis rate of liver disease where patients are not displaying any symptoms.

24 Dec 2018

Kidney patients have the highest number of comorbidities, shows study

A study published in JAMA Network Open showed: nephrologists treat the most complex patients. As ERA-EDTA president Professor Carmine Zoccali explains, kidney patients are highly vulnerable and need special care, but nephrology is a neglected discipline in many European healthcare systems.

24 Dec 2018

Researchers report uncertainty around long-term effectiveness of medications to control knee osteoarthritis pain

Managing osteoarthritis requires long-term treatment for symptoms such as pain and changes in joint structure that can lead to disability.

24 Dec 2018

Whole genome study identifies genetic architecture for diagnosis of polycystic ovary syndrome

In the largest genetic analysis of polycystic ovary syndrome (PCOS) performed to date, an international consortium, including researchers at the Icahn School of Medicine at Mount Sinai, conducted a whole genome association study to identify common genetic architecture for different diagnostic criteria used to define the syndrome.

24 Dec 2018

Implementation of HRRP program associated with increased mortality after discharge

The Hospital Readmissions Reduction Program (HRRP) was created under the Affordable Care Act and hospitals face financial penalties for higher-than-expected 30-day readmission rates for patients with heart failure, heart attack and pneumonia.

24 Dec 2018

Glial cell maturation is severely impaired in patients with Huntington's disease

The neurological disorder Huntington's disease causes behavioral and motor changes, which among other things are a result of dysfunctional maturation or formation of glial cells, the brain's support cells, researchers from the University of Copenhagen demonstrate in a new study based on mice trials.

24 Dec 2018

Risk of heart attack and stroke is high in the months before cancer diagnosis, shows study

Older adults with cancer are more likely to have had a heart attack or stroke in the months prior to their cancer diagnosis compared with similar adults who do not have cancer during the same period, according to a report published online today in Blood. Lung and colon cancers, as well as advanced-staged cancers, appear to be most strongly associated with an elevated risk of heart attack and stroke caused by blood clots in the arteries.

24 Dec 2018

Research identifies factors that help dementia patients and their carers to live well

New research has identified the factors that enable people with dementia and their carers to live as well as possible.

24 Dec 2018

Medical Condition News

Scientists suggest need for new approach to confront side effects of common anti-cancer therapy

Neuronal cell death in Alzheimer's disease may actually not be a bad thing, shows study

Study finds risk factors linked to REM sleep behavior disorder

Breast cancer drugs could tackle lung cancers resistant to targeted therapies

NIPER researcher presents a review on autophagy in neuronal cells

Genetic testing can help personalize diagnosis and treatment of kidney disease, study shows

Yale researchers use arthritis medication to treat patient with disfiguring sarcoidosis

Using untargeted metabolomics to find biomarkers and therapeutic targets for CVD

Study investigates role of miRNAs in anesthetic-induced myocardial conditioning

New method of cancer stem cells activation to destroy tumors

Lupin partners with Abbvie to develop and commercialize new targeted oncology treatments

New mechanism may explain neurons shrinking in Huntington's disease

Simple tests in GP surgeries could increase diagnosis rate of liver disease

Kidney patients have the highest number of comorbidities, shows study

Researchers report uncertainty around long-term effectiveness of medications to control knee osteoarthritis pain

Whole genome study identifies genetic architecture for diagnosis of polycystic ovary syndrome

Implementation of HRRP program associated with increased mortality after discharge

Glial cell maturation is severely impaired in patients with Huntington's disease

Risk of heart attack and stroke is high in the months before cancer diagnosis, shows study

Research identifies factors that help dementia patients and their carers to live well

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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