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Research questions effectiveness of MS medications in slowing disability progression

In people with primary progressive multiple sclerosis (MS), a new study has found no difference in the amount of time before disability worsened between people taking certain medications and those not receiving treatment.

25 Sep 2024

Study sheds light on mechanisms behind liver fibrosis and potential therapies

New research from the University of Pittsburgh School of Pharmacy sheds light on the processes that lead to liver fibrosis and suggests a novel treatment approach for this common and serious condition.

25 Sep 2024

Wrist-based sensors provide insights into sunlight’s impact on depression

Wrist-based activity sensors worn by individuals with depression and those without over the course of two weeks provided evidence for the relationship between daily sunlight exposure and physical activity, according to a study published September 25, 2024, in the open-access journal PLOS Mental Health by Oleg Kovtun and Sandra Rosenthal from Vanderbilt University, U.S.

25 Sep 2024

Stool-based testing offers a new hope for global colorectal cancer screening

"Stool-based test offers a promising solution to reduce the burden of a colonoscopy," experts emphasized on September 21st, during the ICG 19 · Metagenomics for Health (ICG19·MH) & The 2nd MOHA Consortium. The conference was held in Harbin, Heilongjiang Province of China.

25 Sep 2024

Study: Obstructive sleep apnea may be a risk factor for abdominal aortic aneurysms

Obstructive sleep apnea may be a risk factor for developing abdominal aortic aneurysms, according to researchers from the University of Missouri School of Medicine and NextGen Precision Health.

25 Sep 2024

Study links semaglutide to reduced opioid overdose risk in patients with OUD and diabetes

Since being deemed a public health emergency in 2017, opioids are responsible for 72% of drug overdose deaths in the United States, according to the National Center for Drug Abuse Statistics.

25 Sep 2024

Older adults face higher CVD risk post-cancer treatment

Older adults treated for cancer face twice the risk of developing cardiovascular diseases compared to those without cancer. The highest risks are seen in patients with metastatic, hematologic, and lung cancers, especially after chemotherapy.

25 Sep 2024

New AI tool revolutionizes drug discovery for rare diseases

There are more than 7,000 rare and undiagnosed diseases globally.

25 Sep 2024

High body roundness index linked to increased cardiovascular disease risk

Having a high body roundness index (BRI) over a 6-year period was associated with an increased risk of developing cardiovascular disease for adults older than age 45, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

25 Sep 2024

Higher doses of buprenorphine linked to lower emergency visits in opioid use disorder

Adults with opioid use disorder who receive a higher daily dose of the opioid addiction treatment medication buprenorphine may have a lower risk of subsequent emergency department visits or use of inpatient services related to behavioral health (such as for mental health and substance use disorders) than adults receiving the recommended dose, according to an analysis funded by the National Institutes of Health (NIH).

25 Sep 2024

International research initiative aims to improve cardiovascular care for women

The American Heart Association, celebrating 100 years of lifesaving service as the world's leading nonprofit organization focused on heart and brain health for all, is joining with other top cardiovascular research funders around the world to support an international scientific research grant focused on women's cardiovascular health.

25 Sep 2024

Optimized nanoadjuvants enhance in situ tumor vaccine for ovarian cancer

This new article publication from Acta Pharmaceutica Sinica B, discusses how molecular glue triggers degradation of PHGDH by enhancing the interaction between DDB1 and PHGDH.

25 Sep 2024

Combining treatments to boost tumor response in lung cancer

Researchers at the Francis Crick Institute, in collaboration with Revolution Medicines, have tested a combination of treatments in mice with lung cancer and shown that these allow immunotherapies to target non-responsive tumors.

25 Sep 2024

Heme oxygenase 1 and ferroptosis in Kupffer cells linked to heat stroke injury

This new article publication from Acta Pharmaceutica Sinica B, discusses how heme oxygenase 1-mediated ferroptosis in Kupffer cells initiates liver injury during heat stroke.

25 Sep 2024

Deadly high blood pressure during pregnancy is on the rise

Sara McGinnis was pregnant with her second child and something felt off. Her body was swollen. She was tired and dizzy.

25 Sep 2024

One-third of former professional American football players report a punch-drunk reality - CTE

Study found that one-third of former American football players reported perceived CTE, which was significantly associated with a higher risk of suicidality and mental health problems.

25 Sep 2024

Women remain underserved in cardiovascular disease treatment despite advances

Women in the UK, and elsewhere, are still missing out on vital treatment for their No 1 killer - cardiovascular disease - despite significant progress in the medical management of heart disease and stroke, concludes a consensus statement published online in the journal Heart.

24 Sep 2024

Research uncovers mechanism of psychedelic-induced anxiety reduction

A classic psychedelic, similar to LSD, psilocybin and mescalin, was found to activate a cell type in the brain that silences other neighboring neurons, a result that provides insight into how such drugs reduce anxiety, according to a new study.

24 Sep 2024

New FDA award fuels research into autosomal dominant tubulointerstitial kidney disease

Critical Path Institute (C-Path) is thrilled to announce its Polycystic Kidney Disease Outcomes Consortium (PKDOC) has been awarded an Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) focused Broad Agency Announcement (BAA) contract from the U.S. Food and Drug Administration (FDA).

24 Sep 2024

Semaglutide shows promise in treating chronic skin condition in obese patients

A pioneering study, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, demonstrates the significant potential of semaglutide in treating hidradenitis suppurative (HS), a common and chronic skin condition, in people with obesity.

24 Sep 2024