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Targeting miR-4274 and PEX5 can help overcome radioresistance in colorectal cancer

Colorectal cancer (CRC) is a global health concern, and despite advances in radiotherapy, endogenous radioresistance in CRC patients remains a challenge.

9 Jan 2025

New test predicts lung cancer survival better than current standards

Researchers at the Francis Crick Institute, the UCL Cancer Institute and UCLH have shown that a test called ORACLE can predict lung cancer survival at the point of diagnosis better than currently used clinical risk factors.

9 Jan 2025

Smoking before age 15 significantly increases risk of chronic lung disease

A study reveals childhood smoking significantly increases COPD risk in adulthood, highlighting the need for targeted prevention strategies for young smokers.

9 Jan 2025

Could camembert cheese hold the key to better memory?

Myristamide enhances cognitive function and BDNF in mice, indicating Camembert cheese's potential in combating cognitive decline and supporting brain health.

9 Jan 2025

Life expectancy and nursing home admission in people with dementia

The average life expectancy of people diagnosed with dementia ranges from 9 years at age 60 to 4.5 years at age 85 for women and from 6.5 to just over 2 years, respectively, in men, finds a systematic review of the latest evidence in The BMJ today.

9 Jan 2025

Exploring the link between housing and health in autistic populations

Affordable and stable housing is critical to improving health across a person's lifespan. People with disabilities, including autism, comprise a significant share of people in need of housing assistance. However, the intersection of housing and health among individuals with autism is largely unknown because data on public housing and public health are not connected.

9 Jan 2025

Functional characterization of variants improves cancer risk assessment and treatment

Findings from a multi-institutional, international study led by researchers from the Mayo Clinic Comprehensive Cancer Center have significantly advanced the understanding of genetic alterations in the BRCA2 gene, a key player in hereditary cancer risk.

9 Jan 2025

Unraveling the molecular mechanisms of disease-causing mutations

Most mutations which cause disease by swapping one amino acid out for another do so by making the protein less stable, according to a massive study of human protein variants published today in the journal Nature. Unstable proteins are more likely to misfold and degrade, causing them to stop working or accumulate in harmful amounts inside cells.

9 Jan 2025

AI-powered glucose analysis: GPT-4 offers promise with room for refinement

GPT-4 demonstrates its potential in analyzing continuous glucose monitoring data, offering accurate metrics and summaries while highlighting areas for refinement in diabetes care.

8 Jan 2025

Intermittent fasting shows promise in managing obesity and cardiovascular health

A team of scientists led by the University of Granada (UGR), the Public University of Navarra (UPNA) and the CIBER has shown that intermittent fasting (reducing the number of hours of intake and extending the hours of fasting each day) is an effective method for losing weight and improves cardiovascular health in people with obesity problems.

8 Jan 2025

Time-restricted eating rivals Mediterranean diet but falls short for visceral fat loss

Time-restricted eating (TRE) is safe and feasible for weight management but offers no additional benefits over a Mediterranean diet for reducing visceral fat. Early TRE shows promise in reducing subcutaneous fat and improving fasting glucose levels.

8 Jan 2025

Study shows the impact of socioeconomic development on global cancer burden

Cancer remains a significant public health challenge, with the GLOBOCAN 2020 report estimating a staggering 19.3 million new cancer cases and 10 million cancer-related deaths globally.

8 Jan 2025

Stanford researchers develop AI model to enhance cancer prognosis predictions

The melding of visual information (microscopic and X-ray images, CT and MRI scans, for example) with text (exam notes, communications between physicians of varying specialties) is a key component of cancer care.

8 Jan 2025

New brain stem cell discovery could usher in better treatments for glioblastoma

The discovery of a new type of stem cell in the brain could usher in better treatments for the deadliest brain tumor.

8 Jan 2025

New nanoplatform combines pyroptosis and ferroptosis for enhanced cancer treatment

Photoimmunotherapy is an innovative cancer treatment that combines phototherapy with immunotherapy to selectively target and destroy cancer cells.

8 Jan 2025

UC San Diego joins CDC in groundbreaking pandemic preparedness initiative

The Centers for Disease Control and Prevention (CDC) has selected University of California San Diego as one of three partner institutions to establish a groundbreaking pandemic preparedness initiative, the Community and Household Acute Respiratory Illness Monitoring (CHARM) Network.

8 Jan 2025

High-frequency spinal stimulation shows promise in reducing muscle spasticity

Electrical stimulation of the spinal cord is a promising strategy for reestablishing walking after spinal cord injury, recent studies show.

8 Jan 2025

Study reveals how neuropilin2 gene influences autism and epilepsy development

The gene neuropilin2 encodes a receptor involved in cell-cell interactions in the brain and plays a key role in regulating the development of neural circuits.

8 Jan 2025

Researchers uncover molecular mechanisms driving RNA processing defects in Huntington's disease

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other neurodegenerative disorders such as amyotrophic lateral sclerosis, frontotemporal lobar dementia and Alzheimer's disease.

8 Jan 2025

Mutation in ASXL1 gene triggers chain reaction leading to blood disorders

Scientists at La Jolla Institute for Immunology (LJI) have discovered how a mutated gene kicks off a dangerous chain of events during blood cell production.

8 Jan 2025