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Certain sugars in the body play key role in colitis, colon cancer development

An Oklahoma Medical Research Foundation scientist has discovered that certain sugars produced by the body play an important role in the development of colitis and, ultimately, colon cancer. The new finding could potentially lead to therapies for ulcerative colitis, Crohn's disease and colon cancer.

5 May 2016

New study shows Ebola survivors may be at risk of severe vision loss

A new study has shown that Ebola survivors may be at risk of severe vision loss or blindness weeks after being declared virus-free. The research is being presented at the 2016 Annual Meeting of the Association for Research in Vision and Ophthalmology this week in Seattle, Wash.

5 May 2016

Loyola researchers detect tumor gene that may help predict survival outcomes in mouth cancer patients

Loyola researchers have identified a tumor gene that may help to predict survival outcomes in patients with cancer of the mouth and tongue.

5 May 2016

Detailed digital models of human organs could bring substantial benefits to clinical trials

Computer simulations of disease processes and detailed digital models of our organs could provide more accurate monitoring and outcome measurements for clinical trials, according to research being presented in Sheffield today.

5 May 2016

Researchers monitor ICP and PRx to characterize temporal evolution in severe TBI patients

Winner of the Best International Abstract Award, Hadie Adams, presented his research, Characterizing the Temporal Evolution of ICP and Cerebrovascular Reactivity after Severe Traumatic Brain Injury, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

5 May 2016

Research provides new insight into cellular composition of IDH1-mutant gliomas

Winner of the Preuss Research Award, Andrew Venteicher, MD, PhD, presented his research, Cellular Architecture of Human IDH1-mutant Gliomas Revealed Using Single-cell RNA Sequencing, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

5 May 2016

Proton therapy offers new hope to patients with inoperable tumors

An enormous high tech machine is providing new hope to patients across the country with inoperable tumors. Proton therapy is a precise radiation technique that reduces the side effects often accompanied by traditional treatment options. Thanks to this remarkable technology, a new proton therapy center at UF Health Cancer Center - Orlando Health is saving the eyesight of a new mother who was diagnosed with a tumor behind her eye during her second trimester of pregnancy.

5 May 2016

Promising specialty medical home approach to patient-centered, cost-effective care for IBD patients

A specialty medical home--providing expert medical care coordinated with attention to social support and mental health--is a promising new approach to patient-centered, cost-effective care for patients with Crohn's disease and ulcerative colitis, according to a special "Future Directions" paper in the May issue of Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America. The journal is published by Wolters Kluwer.

5 May 2016

Finding treatments for rare diseases: an interview with Dr Richard Thompson

It is estimated that around 400 rare diseases have licenced treatments, and a large proportion of these are a consequence of orphan drug legislation, which has helped to incentivise the production of drugs for small patient populations.

4 May 2016

Candida yeast infections more common in men with schizophrenia or bipolar disorder

In a study prompted in part by suggestions from people with mental illness, Johns Hopkins researchers found that a history of Candida yeast infections was more common in a group of men with schizophrenia or bipolar disorder than in those without these disorders, and that women with schizophrenia or bipolar disorder who tested positive for Candida performed worse on a standard memory test than women with schizophrenia or bipolar disorder who had no evidence of past infection.

4 May 2016

New 3D-printed talus replacement surgery to treat avascular necrosis provides life-changing experience

The talus is the part ankle that allows the foot to move in all different directions. High impact injuries like falls, or traffic accidents can cause the talus bone to be fractured, and a high percentage of these injuries result in avascular necrosis (AVN)—the death of the bone. In a first-of-its-kind procedure using 3D printing technology, internationally renowned orthopedic surgeon Dr. Mark Myerson, Director, The Institute for Foot and Ankle Reconstruction at Mercy Medical Center, explains how a talus replacement, tailored to the patient's specific dimensions, can result in a "life-changing experience" for the patient.

4 May 2016

Innovative noise reduction technology SEDA helps tackle babble signals from cochlear implants

Wearers of cochlear implants and hearing aids often have difficulty teasing out what someone is saying over "babble" -- the cacophony of other talkers -- and other ambient sounds. New York University researchers have devised a novel solution: an algorithmic approach that, like making drinkable water from pond water, distills the talker's voice from a turbid wash of noise.

4 May 2016

Researchers find gene variants that predict adverse effects of hyperthyroidism drugs

Researchers and doctors at Uppsala University, along with Swedish and international collaboration partners, have found gene variants that predict the risk of a serious adverse reaction to drugs used for the treatment of hyperthyroidism. The results are published in The Lancet Diabetes & Endocrinology.

4 May 2016

High prevalence of depression alongside COPD can impact overall health, treatment effectiveness

Although there have been discussions about chronic obstructive pulmonary disease (COPD), a condition impacting 24 million Americans, and depression, there has been little research showing the impact depression has on patients with COPD. Two studies published in the April issue of the journal CHEST found one in four patients with COPD suffer from depressive symptoms, and if not treated, those symptoms can have a negative effect on their overall health and treatment effectiveness.

4 May 2016

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

University of Alabama at Birmingham researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.

4 May 2016

LALES study analyzes risk, prevalence of early and late stage AMD among Latinos

The University of Southern California Roski Eye Institute researchers and clinicians published results of the largest population-based study of adult Latinos and age-related macular degeneration (AMD) in the National Eye Institute-funded "Los Angeles Latino Eye Study." The study, published in JAMA Ophthalmology, is the first to analyze the risk and prevalence of early and late stage AMD and its impact on quality of life for older Latinos.

4 May 2016

Respiratory tract infection in infants linked with increased T1D risk

In a study appearing in the May 3, 2016 issue of JAMA, Anette-Gabriele Ziegler, M.D., of Helmholtz Zentrum Munchen, Munich, Germany, and colleagues examined associations between infection types during the first 2 years of life and between respiratory tract infections in the first 6 months and type l diabetes (T1D). Viral infections, particularly enteroviruses, have been hypothesized to cause T1D. Recent studies suggest that respiratory tract infections are associated with increased T1D risk if they are encountered within the first 6 months.

4 May 2016

Lund study shows transplanted nerve cells can survive for many years in diseased human brain

In the late 1980s and over the 1990s, researchers at Lund University in Sweden pioneered the transplantation of new nerve cells into the brains of patients with Parkinson's disease. The outcomes proved for the first time that transplanted nerve cells can survive and function in the diseased human brain. Some patients showed marked improvement after the transplantation while others showed moderate or no relief of symptoms.

4 May 2016

Diabetes risk linked to increased dosage, duration and timing of steroids

Glucocorticoid (or steroid) therapy, prescribed to around half of patients with rheumatoid arthritis, is a known risk factor for developing diabetes. A study from The University of Manchester has found how the risk of diabetes increases in relation to the dosage, duration and timing of steroids.

4 May 2016

Aggregation of SOD1 protein in nerve cells can lead to ALS

Persons with the serious disorder ALS, can have a genetic mutation that causes the protein SOD1 to aggregate in motor neurons in the brain and spinal cord. Researchers at Umea University have discovered that, when injected into mice, the SOD1 aggregation spreads rapidly leading to ALS. The discovery has been described in the Journal of Clinical Investigation.

4 May 2016

Medical Condition News

Certain sugars in the body play key role in colitis, colon cancer development

New study shows Ebola survivors may be at risk of severe vision loss

Loyola researchers detect tumor gene that may help predict survival outcomes in mouth cancer patients

Detailed digital models of human organs could bring substantial benefits to clinical trials

Researchers monitor ICP and PRx to characterize temporal evolution in severe TBI patients

Research provides new insight into cellular composition of IDH1-mutant gliomas

Proton therapy offers new hope to patients with inoperable tumors

Promising specialty medical home approach to patient-centered, cost-effective care for IBD patients

Finding treatments for rare diseases: an interview with Dr Richard Thompson

Candida yeast infections more common in men with schizophrenia or bipolar disorder

New 3D-printed talus replacement surgery to treat avascular necrosis provides life-changing experience

Innovative noise reduction technology SEDA helps tackle babble signals from cochlear implants

Researchers find gene variants that predict adverse effects of hyperthyroidism drugs

High prevalence of depression alongside COPD can impact overall health, treatment effectiveness

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

LALES study analyzes risk, prevalence of early and late stage AMD among Latinos

Respiratory tract infection in infants linked with increased T1D risk

Lund study shows transplanted nerve cells can survive for many years in diseased human brain

Diabetes risk linked to increased dosage, duration and timing of steroids

Aggregation of SOD1 protein in nerve cells can lead to ALS

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

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