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Cholesterol drug evacetrapib fails to reduce risk of cardiovascular events

Despite lowering low-density lipoprotein (LDL), known as "bad" cholesterol, while markedly increasing levels of high-density lipoprotein (HDL), or "good" cholesterol, a large clinical trial to investigate the cholesterol drug evacetrapib was discontinued early after a preliminary analysis showed it did not reduce rates of major adverse cardiovascular events, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Understanding idiopathic pulmonary fibrosis: an interview with Michael Durheim, M.D.

IPF is a rare and fatal lung disease that causes permanent scarring of the lungs, leading to debilitating shortness of breath and cough in affected patients. It affects as many as 132,000 Americans, most commonly those over the age of 65.

4 Apr 2016

Janssen announces CHMP positive opinion for use of paliperidone palmitate 3-monthly injection for schizophrenia treatment

Janssen UK announced today that the Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion recommending the use of paliperidone palmitate 3-monthly injection for the maintenance treatment of schizophrenia in the European Union.

4 Apr 2016

CHMP recommends conditional marketing authorisation for Janssen’s daratumumab

Janssen-Cilag announced today that the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended the granting of a conditional marketing authorisation for first-in-class CD38 immunotherapy daratumumab in the European Union.

4 Apr 2016

NICE issues positive guidance on use of electroCore’s gammaCore treatment for migraine and cluster headache

The UK’s National Institute of Health and Care Excellence has published guidance that electroCore’s non-invasive vagus nerve stimulation treatment (gammaCore) for the prevention and acute treatment of migraine and cluster headache is safe and can now be used in the NHS.

4 Apr 2016

Leading entrepreneurs, innovators to take part in Royal Society of Medicine's 12th Medical Innovations Summit

A group of leading entrepreneurs and innovators will be gathering at the Royal Society of Medicine on Saturday 16 April to take part in the Society’s 12th Medical Innovations Summit. Providing a twice-yearly platform for the presentation and discussion of inspirational ideas and developments in the field of medicine and healthcare, the Summits encourage innovators at the very beginning of their careers, as well as established clinicians and academics.

4 Apr 2016

Study: Age and gender affects prevalence of certain peripheral vascular diseases

New findings from large-scale studies of more than 3.6 million people who underwent screening for cardiovascular disease reveals that a person's age and gender affects the prevalence of certain types of peripheral vascular diseases (PVD), and that diabetes is a major risk factor for developing these diseases, even in patients without heart disease.

2 Apr 2016

New proposal suggests innovative approach to improve cancer care for FNIM Canadians

With the number of First Nation, Inuit, and Métis Canadians diagnosed with cancer currently growing, it turns out that little is done to study and address their unique needs in a timely enough manner.

2 Apr 2016

Plitidepsin in combination with dexamethasone shows top-line results in Phase III multiple myeloma trial

PharmaMar today announced positive top-line results of its Phase III clinical trial -ADMYRE- with Aplidin (plitidepsin) in combination with dexamethasone versus dexamethasone alone in patients with relapsed/refractory multiple myeloma (MM).

2 Apr 2016

USC study finds coffee consumption decreases colorectal cancer risk

Whether you like your coffee black, decaf, half-caff or even instant, feel free to drink up. Researchers at the University of Southern California (USC) Norris Comprehensive Cancer Center of Keck Medicine of USC have found that coffee consumption decreases the risk of colorectal cancer.

2 Apr 2016

Joslin scientists identify new mechanism in development of obesity-induced insulin resistance

In obesity, the body's immune system can treat tissues as if they are suffering from a low-grade chronic infection. This obesity-induced inflammation is an important contributor to insulin resistance, a condition that can progress into type 2 diabetes.

2 Apr 2016

U of S-led researchers develop novel class of compounds for effective cancer treatment

A novel class of compounds developed by a University of Saskatchewan-led research team could yield more effective and less toxic chemotherapy drugs to treat cancer.

2 Apr 2016

New SPOR Network launched to transform health outcomes of diabetes patients

A new national research network was launched today to transform the health outcomes of individuals with diabetes and its related complications. It will be led by two of Canada's top researchers in the field and includes researchers conducting leading-edge health and biomedical research at nine institutions across the country.

2 Apr 2016

Better understanding of cell death mechanism could lead to more efficient cancer immunotherapy

Researchers in the group of Prof. Dr. Peter Vandenabeele show that killed tumour cells can serve as a potent vaccine that stimulates the immune system to prevent the outgrowth of cancer cells.

2 Apr 2016

Lund researchers discover new biomarker that can predict type 2 diabetes risk

Researchers at Lund University in Sweden have found a new type of biomarker that can predict the risk of type 2 diabetes, by detecting epigenetic changes in specific genes through a simple blood test. The results are published today in Nature Communications.

2 Apr 2016

MicroRNA controls tumor cell proliferation in most aggressive large B-cell lymphoma

A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine showed that a microRNA called miR-181a dampens signals from the cancer-driving NFκB protein pathway in the most aggressive large B-cell lymphomas (DLBCL). By reducing NFκB signaling, miR-181a controls tumor cell proliferation and survival and could be the target of novel therapies. The study was published in the journal Blood.

2 Apr 2016

Better oral hygiene, regular dental visits could slow down cognitive decline in older adults

Better oral hygiene and regular dental visits may play a role in slowing cognitive decline as people age, although evidence is not definitive enough to suggest that one causes the other.

2 Apr 2016

Common viruses could produce mild to lethal cardiac injury

A review article has been published in the journal Current Pharmaceutical Design which provides an overview of therecent literature discussing the different clinical forms of heart disease resulting from virus infections including the prognosis, and current therapies.

2 Apr 2016

Loyola to conduct clinical trial of new procedure to treat atrial fibrillation

Loyola Medicine is enrolling patients in a landmark clinical trial of a new procedure to treat atrial fibrillation, the most common type of irregular heartbeat.

2 Apr 2016

Mindfulness training can help manage painful cycles of thoughts in veterans with PTSD

Like an endlessly repeating video loop, horrible memories and thoughts can keep playing over and over in the minds of people with post-traumatic stress disorder. They intrude at the quietest moments, and don't seem to have an off switch.

2 Apr 2016

Medical Condition News

Cholesterol drug evacetrapib fails to reduce risk of cardiovascular events

Understanding idiopathic pulmonary fibrosis: an interview with Michael Durheim, M.D.

Janssen announces CHMP positive opinion for use of paliperidone palmitate 3-monthly injection for schizophrenia treatment

CHMP recommends conditional marketing authorisation for Janssen’s daratumumab

NICE issues positive guidance on use of electroCore’s gammaCore treatment for migraine and cluster headache

Leading entrepreneurs, innovators to take part in Royal Society of Medicine's 12th Medical Innovations Summit

Study: Age and gender affects prevalence of certain peripheral vascular diseases

New proposal suggests innovative approach to improve cancer care for FNIM Canadians

Plitidepsin in combination with dexamethasone shows top-line results in Phase III multiple myeloma trial

USC study finds coffee consumption decreases colorectal cancer risk

Joslin scientists identify new mechanism in development of obesity-induced insulin resistance

U of S-led researchers develop novel class of compounds for effective cancer treatment

New SPOR Network launched to transform health outcomes of diabetes patients

Better understanding of cell death mechanism could lead to more efficient cancer immunotherapy

Lund researchers discover new biomarker that can predict type 2 diabetes risk

MicroRNA controls tumor cell proliferation in most aggressive large B-cell lymphoma

Better oral hygiene, regular dental visits could slow down cognitive decline in older adults

Common viruses could produce mild to lethal cardiac injury

Loyola to conduct clinical trial of new procedure to treat atrial fibrillation

Mindfulness training can help manage painful cycles of thoughts in veterans with PTSD

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

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