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Stanford team uses natural cell death mechanism to kill cancer cells

Our bodies divest themselves of 60 billion cells every day through a natural process of cell culling and turnover called apoptosis.

27 Nov 2024

Study reveals protein mobility defect as a key factor in chronic diseases

Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically taxing, and the number of people with such diseases is growing.

27 Nov 2024

Research shows "Alzheimer's in a dish" model can accelerate drug discovery

A decade ago, researchers introduced a new model for studying Alzheimer's disease. Known as "Alzheimer's in a dish," the model uses cultures of mature brain cells suspended in a gel to recapitulate what takes place in the human brain over 10 to 13 years in just six weeks.

27 Nov 2024

Younger age at type 2 diabetes diagnosis increases mortality risk

Research found that younger age at type 2 diabetes diagnosis is associated with higher risks of cardiovascular and all-cause mortality, emphasizing the need for early prevention and personalized management strategies.

27 Nov 2024

Philadelphia beverage tax: Did it curb childhood obesity?

The 2017 Philadelphia beverage tax aimed to reduce sugar-sweetened beverage consumption and improve pediatric health. While it significantly reduced sugary drink purchases, its impact on overall pediatric weight was limited, with minor changes observed in specific subgroups.

27 Nov 2024

IQWiG evaluates smoking cessation drugs for severe tobacco dependence treatment

By law, smokers with severe tobacco dependence are entitled to receive one-off drug therapy for smoking cessation as part of evidence-based programmes reimbursed by the German statutory health insurance (SHI).

27 Nov 2024

Study unveils key mechanism in Alzheimer's disease

A new study from the University of Liverpool represents a significant step forward in scientists' understanding of Alzheimer's disease.

27 Nov 2024

Exposure to air pollutants raises risk of persistent long-COVID symptoms

Exposure to air pollutants (PM2.5 and PM10) is associated with an increased risk of persistent long-COVID symptoms, partly due to its impact on the severity of the acute infection.

27 Nov 2024

Social media's role in shaping public attitudes toward obesity

Through an analysis of tweets (now rebranded X) relating to obesity published between April 2019 and December 2022, a study conducted by the Geneva University Hospitals (HUG) and the University of Geneva (UNIGE) has revealed that most of these tweets convey negative sentiments about overweight.

27 Nov 2024

New gold-based drug proves to be more potent than standard chemotherapy

A new gold-based drug can slow tumour growth in animals by 82% and target cancers more selectively than standard chemotherapy drugs, according to a study by Australian and Indian researchers.

27 Nov 2024

Study finds unexpected patterns in insulin needs for type 1 diabetes

Factors beyond carbohydrates have a substantial influence on blood glucose levels meaning current automated insulin delivery systems miss vital information required for glucose regulation, a new study has found.

27 Nov 2024

GLP-1 receptor agonists reduce kidney failure risk and cardiovascular events

Researchers evaluate the effects of glucagon-like peptide-1 receptor agonists on kidney and cardiovascular outcomes.

27 Nov 2024

Depression increases chances of experiencing menstrual pain

Scientists investigate the genetic relationship between depression and dysmenorrhea.

27 Nov 2024

Soccer heading may cause long-term brain damage

Soccer heading may cause more damage to the brain than previously thought, according to a study being presented next week at the annual meeting of the Radiological Society of North America (RSNA).

27 Nov 2024

Insulin resistance linked to increased risk of aortic stenosis

A large new population study of men over 45 indicates insulin resistance may be an important risk factor for the development of the world's most common heart valve disease – aortic stenosis (AS).

27 Nov 2024

Exploring sleep's role in blood pressure regulation across genders

You may have heard sleep described as something of a magic pill for the body. With the right amount, timing, and quality, it can work wonders - strengthen the immune system, improve blood sugar, even decrease the risk of heart attacks and strokes.

27 Nov 2024

Study links cell death pathway to cancer resistance and growth

A new study has uncovered an unexpected way cancer cells can escape the immune system, making it harder for treatments to work. The study, published in Cancer Cell, explains how a type of cancer cell death can actually make tumors grow faster by turning off the immune system's ability to fight the cancer.

27 Nov 2024

MR1 molecule and vitamin B6 could unlock new paths for cancer immunotherapy

Effective immunity hinges on the ability to sense infection and cellular transformation. In humans, there is a specialized molecule on the surface of cells termed MR1.

27 Nov 2024

PD-1 deficiency reveals the impact of checkpoint inhibition on B cell function

A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint inhibitors experience increased susceptibility to common infections.

27 Nov 2024

Cryoablation for PFO closure in AF patients undergoing PVI

New research shows that cryoablation is a safe and effective approach to close congenital patent foramen ovale (PFO, a small hole in the heart) in patients with atrial fibrillation (AF) undergoing pulmonary vein isolation (PVI) in a single procedure.

27 Nov 2024