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Understanding the surprising link between HDL cholesterol quality and Alzheimer's risk

Higher levels of HDL-C - known as the "good cholesterol" - have been shown to correlate with heightened risk for Alzheimer's disease.

12 Oct 2024

New computational pipeline revolutionizes personalized cancer vaccine design

Ludwig Cancer Research scientists have developed a full, start-to-finish computational pipeline that integrates multiple molecular and genetic analyses of tumors and the specific molecular targets of T cells and harnesses artificial intelligence algorithms to use its output to design personalized cancer vaccines for patients.

12 Oct 2024

Unique protein complex found to influence brain function and anxiety

Scientists at Université de Montréal and its affiliated Montreal Clinical Research Institute (IRCM) have uncovered unique roles for a protein complex in the structural organization and function of brain cell connectivity, as well as in specific cognitive behaviors.

12 Oct 2024

University of Michigan receives grant to study pain management in opioid use disorder

The University of Michigan will use a new $3.6 million federal grant to study how pain and opioids after surgery impact people with opioid use disorder, how guidelines might be adjusted to address post-surgical pain and how to prevent opioid-related harms.

12 Oct 2024

Early signs of inflammatory bowel disease detected in newborns

Across the Western world, the prevalence of these chronic and serious conditions, which have no cure, is rising. In Denmark alone, 50,000 people suffer from either Crohn's disease or ulcerative colitis, which represents a doubling in cases over the past 20 years.

12 Oct 2024

JRC releases a new CRM to aid the fight against beta-thalassemia

Our blood is a window to our health. Doctors examine biomarkers in our blood to determine our health status.

12 Oct 2024

Multidisciplinary approach improves quality of life in functional movement disorders

The research team of the Neurology Department Movement Disorders Unit at the Virgen del Rocío University Hospital and the Movement Disorders group of the Institute of Biomedicine of Seville - IBiS, in collaboration with researchers from the Mental Health Clinical Management Unit and the Translational Psychiatry group coordinated by Benedicto Crespo Facorro (HUVR-IBiS/CIBERSAM), has published a randomized clinical trial demonstrating for the first time that a multidisciplinary approach integrating specific physiotherapy and cognitive-behavioral therapy is effective in improving the symptoms and physical aspects of the quality of life of patients with functional movement disorders.

12 Oct 2024

Umeå University discovers critical mechanisms in stem cell differentiation

A study led by Umeå University, Sweden, presents new discoveries about how stem cells develop and transition into specialised cells. The discovery can provide increased understanding of how cells divide and grow uncontrollably so that cancer develops.

12 Oct 2024

Researchers develop innovative mouse model for studying cancer immunotherapy

Immunity plays a central role in the fight against cancer. Many of the current immunotherapies aim at helping the patient's immune system to better recognize cancer cells - by using engineered antibodies - or by simply providing it with new cells, pre-equipped to search and destroy cancer.

12 Oct 2024

Innovative tissue expansion technique transforms conventional microscopy capabilities

A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before imaging it - a technique that allows them to achieve nanoscale resolution with a conventional light microscope.

12 Oct 2024

Harnessing neural networks to forecast treatment outcomes in small cell lung cancer

As immunotherapy makes breakthrough progress in the treatment of small cell lung cancer (SCLC), predicting treatment outcomes has become a focal point in clinical practice. Immunotherapy combined with chemotherapy has been approved as first-line therapy for small cell lung cancer due to its survival benefit in randomized controlled trials.

12 Oct 2024

Innovative approaches to lymphatic pain relief in breast cancer patients

Among the 7.8 million women with breast cancer worldwide, at least 33% to 44% are affected by lymphatic pain. Breast cancer survivors usually suffer lymphatic pain in the ipsilateral body or upper limb, and pharmacological approaches are not effective for lymphatic pain.

12 Oct 2024

Newly identified 'headspin hole' affects breakdancers’ scalp health

Breakdancers may be at risk of developing a condition caused by repeatedly doing a cardinal move of their practice and performance - the headspin - warn doctors in the journal BMJ Case Reports.

12 Oct 2024

Gene editing enhances immunotherapy success by preventing T-cell exhaustion

Immunotherapy, using a patient's own immune system to treat disease, has shown promise in some patients with cancer but has not worked in most.

12 Oct 2024

Researchers uncover new mechanism of stem cell differentiation linked to cancer progression

A study led by Umeå University, Sweden, have made new discoveries about how stem cells develop and transition into specialized cells. The discovery can provide increased understanding of how cells divide and grow uncontrollably so that cancer develops.

12 Oct 2024

New research explores hydrogen sulfide as treatment for obesity

Therapies that deliver hydrogen sulfide to cells could one day become the basis of new treatments for obesity and related diseases, new research has concluded.

10 Oct 2024

Oral health strategies for healthy aging: A call to action

Research explores the connection between aging populations and oral health, proposing an integrated model to address health challenges in older adults, with a focus on policy changes in the UK.

10 Oct 2024

Mount Sinai launches new center for complex chronic illnesses

Mount Sinai's Department of Rehabilitation and Human Performance has announced the grand opening of the Cohen Center for Recovery From Complex Chronic Illnesses (CoRE), providing clinical care for patients with conditions such as long Lyme disease/Lyme+, long COVID, and other infection-associated complex chronic illnesses such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Ehlers-Danlos syndrome (EDS).

10 Oct 2024

Excess sugar consumption triggers inflammation and dysbiosis, worsening periodontal disease

Research explores how excessive sugar consumption can drive systemic inflammation, disrupt the gut and oral microbiomes, and contribute to periodontal inflammation, with implications for global health.

10 Oct 2024

New funding to strengthen stroke care systems in Minnesota and South Dakota

Across the United States, more than 90% of stroke patients have some form of disability as a result and more than 11% experience a second stroke within a year.

10 Oct 2024