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MTG Biotherapeutics' MTG-201 granted FDA Orphan Drug Designation for malignant mesothelioma treatment

MTG Biotherapeutics, an immuno-oncology company developing novel therapeutics for the treatment of cancer, today announced that the US Food and Drug Administration has granted Orphan Drug Designation for MTG-201, an advanced biologic therapy targeting Dickkopf-3 gene defects in various cancers, for the treatment of malignant mesothelioma.

23 Aug 2015

Number of dementia patients stabilizing experts claim

Risk of dementia may be falling due to improved education and living conditions, and better prevention and treatment of vascular diseases, highlighting the need for policies to improve health across the life course.

21 Aug 2015

Low rate of mortality from breast cancer after DCIS diagnosis

Research published this week estimates that the risk of dying from early stage breast cancer within 20 years of diagnosis is very low (3.3%).

21 Aug 2015

IQWiG dossier assessment finds added benefit of afatinib in patients with certain mutations

Afatinib (trade name: Giotrif) has been approved since September 2013 for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with activating EGF receptor mutations who have not been treated with an EGF receptor tyrosine-kinase inhibitor (EGFR TKI).

21 Aug 2015

Novel wound closure technique may reduce complication rates for patients with scoliosis

Patients with scoliosis who undergo surgery may be less likely to develop an infection or other complications after the procedure when a novel wound closure technique pioneered at NYU Langone Medical Center is utilized, according to new research.

21 Aug 2015

Loyola University Medical Center first in Illinois to offer new, noninvasive test for heart disease

Loyola University Medical Center is the first and only hospital in Illinois to offer a new, noninvasive technology to test for coronary artery disease.

21 Aug 2015

Study: Women warriors at no greater risk than men for developing PTSD

While past research on the question has been mixed, a new study by Defense and Veterans Affairs researchers suggests that women in the military are at no greater risk than men for developing posttraumatic stress disorder, given similar experiences--including combat.

21 Aug 2015

Two proteins that help cells eliminate trash may contribute to development of Parkinson's disease

Two proteins that share the ability to help cells deal with their trash appear to need each other to do their jobs and when they don't connect, it appears to contribute to development of Parkinson's disease, scientists report.

21 Aug 2015

Researchers establish structure of important tumor-suppressing protein

An international group of researchers led by Carnegie Mellon University physicists Mathias Lösche and Frank Heinrich have established the structure of an important tumor suppressing protein, PTEN. Their findings provide new insights into how the protein regulates cell growth and how mutations in the gene that encodes the protein can lead to cancer.

21 Aug 2015

Potential biomarker could help prevent pre-diabetic individuals from developing Type II diabetes

Virginia Tech researchers have identified a biomarker in pre-diabetic individuals that could help prevent them from developing Type II diabetes.

21 Aug 2015

New study finds significant association between ADHD and TBI

A new study has found a "significant association" between adults who have suffered a traumatic brain injury at some point in their lives and who also have attention deficit hyperactive disorder.

21 Aug 2015

Researchers find effectiveness of ramelteon for treatment of sleep disturbances after TBI

Kessler researchers found preliminary evidence for the effectiveness of ramelteon for the treatment of sleep disturbances after traumatic brain injury (TBI). The article, "Archives of Physical Medicine and Rehabilitation on May 28, 2015. Authors are Anthony Lequerica, PhD, and Nancy Chiaravalloti, PhD, of Kessler Foundation, Neil Jasey, MD, of Kessler Institute for Rehabilitation, and Jaclyn Portelli Tremont, MA, of Robert Wood Johnson Medical School, Rutgers University.

21 Aug 2015

FDA accepts Allergan's resubmission of BOTOX sBLA for treatment of adults with upper limb spasticity

Allergan plc, a leading global pharmaceutical company today announced that the U.S. Food and Drug Administration has accepted the company's resubmission of its Supplemental Biologics License Application (sBLA) for BOTOX (onabotulinumtoxinA) for the treatment of adults with lower limb (involving ankle and toe muscles) spasticity in adults.

20 Aug 2015

Janus collaborates with Roche to develop TLR inhibitor to address several autoimmune diseases

Janus Biotherapeutics today announced that they have entered into a collaboration with Roche for the development of a small molecule toll-like receptor (TLR) inhibitor with the potential to address several autoimmune diseases. TLRs are an important class of proteins that play a key role in the innate immune system.

20 Aug 2015

NYBC, UC Davis Health System partner to manufacture potential stem cell therapies

New York Blood Center today announced a new collaboration with the University of California, Davis, Health System to manufacture specialized lines of stem cells as potential therapies for repair and regeneration of retina, kidney, lung and liver tissue, as well as for the treatment of neurodegenerative disorders such as Parkinson's, Alzheimer's and Huntington's disease.

20 Aug 2015

Tiny nanocrystals could be used in advanced medical imaging technologies to light up cancer cells

Researchers in China have developed tiny nanocrystals that could be used in the next generation of medical imaging technologies to light up cancer cells.

20 Aug 2015

First Virtual Support Network launched for women living with atrial fibrillation

WomenHeart: The National Coalition for Women with Heart Disease today announced the launch of the first Virtual Support Network specifically for women living with atrial fibrillation (afib) – a serious heart condition that carries a high risk of stroke.

20 Aug 2015

STA inks license and commercialisation agreement with PharmaMar for APLIDIN (plitidepsin)

Australian biopharmaceutical company Specialised Therapeutics Australia has struck an exclusive license and commercialisation agreement with European pharmaceutical partner company PharmaMar to market and distribute the novel oncology drug APLIDIN (plitidepsin) in Australia and New Zealand.

20 Aug 2015

EMPA-REG OUTCOME trial demonstrates superiority of Jardiance in T2D patients at risk for CV events

Boehringer Ingelheim and Eli Lilly and Company today announced positive top-line results from EMPA-REG OUTCOME. This is a long-term clinical trial investigating cardiovascular (CV) outcomes for Jardiance (empagliflozin) in more than 7,000 adults with type 2 diabetes (T2D) at high risk for CV events.

20 Aug 2015

GMP protein can improve gastrointestinal health by protecting digestive system from pathogens

The protein glycomacropeptide (GMP) is derived from whey, the liquid by-product of the cheese-making process. GMP contains low amounts of the amino acid phenylalanine. Individuals who suffer from phenylketonuria—a metabolic disorder that causes cognitive impairment when phenylalanine level is too high—can use GMP as an alternative protein source. GMP supplementation has also been observed to improve gastrointestinal health by protecting the digestive system from pathogens and by having an anti-inflammatory effect.

20 Aug 2015

Medical Condition News

MTG Biotherapeutics' MTG-201 granted FDA Orphan Drug Designation for malignant mesothelioma treatment

Number of dementia patients stabilizing experts claim

Low rate of mortality from breast cancer after DCIS diagnosis

IQWiG dossier assessment finds added benefit of afatinib in patients with certain mutations

Novel wound closure technique may reduce complication rates for patients with scoliosis

Loyola University Medical Center first in Illinois to offer new, noninvasive test for heart disease

Study: Women warriors at no greater risk than men for developing PTSD

Two proteins that help cells eliminate trash may contribute to development of Parkinson's disease

Researchers establish structure of important tumor-suppressing protein

Potential biomarker could help prevent pre-diabetic individuals from developing Type II diabetes

New study finds significant association between ADHD and TBI

Researchers find effectiveness of ramelteon for treatment of sleep disturbances after TBI

FDA accepts Allergan's resubmission of BOTOX sBLA for treatment of adults with upper limb spasticity

Janus collaborates with Roche to develop TLR inhibitor to address several autoimmune diseases

NYBC, UC Davis Health System partner to manufacture potential stem cell therapies

Tiny nanocrystals could be used in advanced medical imaging technologies to light up cancer cells

First Virtual Support Network launched for women living with atrial fibrillation

STA inks license and commercialisation agreement with PharmaMar for APLIDIN (plitidepsin)

EMPA-REG OUTCOME trial demonstrates superiority of Jardiance in T2D patients at risk for CV events

GMP protein can improve gastrointestinal health by protecting digestive system from pathogens

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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