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Study of genetic risk factors of IBD in African-Americans published in Gastroenterology journal

Researchers at the Johns Hopkins University School of Medicine, along with colleagues at Emory University and Cedars-Sinai, have published in the journal Gastroenterology the first major, in-depth analysis of genetic risk factors of inflammatory bowel disease in African-Americans.

26 Aug 2015

Longer-lasting colonoscopies associated with lower cancer rates

If a colonoscopy seems like the type of thing you'd like to get done with quickly, think again. Research by a Veterans Affairs team has confirmed that longer-lasting colonoscopies are associated with lower cancer rates.

26 Aug 2015

Inpatient palliative care visits associated with improved quality of life for patients with heart failure

A recent randomized trial conducted by researchers at Abbott Northwestern Hospital, part of Allina Health, found that inpatient palliative care (PC) visits were associated with improved quality of life and symptom burden for patients with heart failure (HF).

26 Aug 2015

UH research points to promising target in treatment of pancreatic cancer

Pancreatic cancer is extremely deadly and often has a poor prognosis. Ranked as the fourth deadliest cancer in the U.S. and poised to move up within the next few years, pancreatic cancer is very difficult to detect in its early stages. Seldom diagnosed early and typically spreading rapidly, the disease has no effective treatment once it advances.

26 Aug 2015

New research could potentially yield novel platform for cancer vaccines

New research led by Wyss Core Faculty member David Mooney, Ph.D., in collaboration with researchers at the Dana-Farber Cancer Institute could potentially yield a new platform for cancer vaccines. Leveraging a biologically inspired sponge-like gel called "cryogel" as an injectable biomaterial, the vaccine delivers patient-specific tumor cells together with immune-stimulating biomolecules to enhance the body's attack againstcancer.

26 Aug 2015

Persistent leukemia-associated genetic mutations linked to increased risk of relapse, reduced overall survival

In preliminary research, the detection of persistent leukemia-associated genetic mutations in at least 5 percent of bone marrow cells in day 30 remission samples among adult patients with acute myeloid leukemia was associated with an increased risk of relapse and reduced overall survival, according to a study in the August 25 issue of JAMA.

26 Aug 2015

Simple modification can increase effectiveness of emergency treatment for patients with supraventricular tachycardia

A simple, safe and cost-free modification to a physical technique used to treat patients in the emergency department with an abnormally fast heart rhythm could improve its effectiveness by more than a quarter, according to a study published in The Lancet today (25 August 2015).

26 Aug 2015

Study reveals how inflammation triggers colon cancer cells to metastasize

A new Arizona State University research study led by Biodesign Institute executive director Raymond DuBois, M.D., Ph.D., has identified for the first time the details of how inflammation triggers colon cancer cells to spread to other organs, or metastasize.

26 Aug 2015

GW researchers find potential link between microbes in the throat and schizophrenia

In the most comprehensive study to date, researchers at the George Washington University have identified a potential link between microbes (viruses, bacteria and fungi) in the throat and schizophrenia. This link may offer a way to identify causes and develop treatments of the disease and lead to new diagnostic tests.

26 Aug 2015

Lingering cancer-related mutations linked to increased risk of relapse, poor survival in leukemia patients

For patients with an often-deadly form of leukemia, new research suggests that lingering cancer-related mutations - detected after initial treatment with chemotherapy - are associated with an increased risk of relapse and poor survival.

26 Aug 2015

Omega-3 supplements fail to slow cognitive decline in older persons, NIH clinical study shows

While some research suggests that a diet high in omega-3 fatty acids can protect brain health, a large clinical trial by researchers at the National Institutes of Health found that omega-3 supplements did not slow cognitive decline in older persons. With 4,000 patients followed over a five-year period, the study is one of the largest and longest of its kind.

26 Aug 2015

Mental visual imagery training may improve AM/EFT functioning in RR-MS patients

Patients with relapsing-remitting multiple sclerosis (RR-MS), the most common form of the disease, often have deficits in two neuropsychological functions, autobiographical memory (AM) and episodic future thinking (EFT), which impact quality of life.

26 Aug 2015

MorphoSys, Immatics partner to develop novel antibody-based therapies against multiple proprietary cancer antigens

MorphoSys AG and Immatics Biotechnologies GmbH announced today a strategic alliance to generate novel antibody-based therapeutics against multiple proprietary cancer antigens recognized by T cells.

26 Aug 2015

Amgen to present data on Repatha (evolocumab) and observational studies at ESC Congress 2015

Amgen today announced that it will present six abstracts at the upcoming ESC Congress 2015, organized by the European Society of Cardiology, being held Aug. 29 – Sept. 2 in London.

26 Aug 2015

FDA, EMA accept filing applications for Boehringer Ingelheim's afatinib to treat patients with advanced SCC of the lung

Boehringer Ingelheim today announced that both the U.S. Food and Drug Administration and the European Medicines Agency have accepted filing applications for afatinib for the treatment of patients with advanced squamous cell carcinoma (SCC) of the lung progressing after treatment with first-line chemotherapy.

26 Aug 2015

Clementia expands enrollment to include children with FOP in ongoing Phase 2 clinical trial

Clementia Pharmaceuticals, Inc. today announced the initiation of enrollment of children as young as 6 years old in the company's ongoing Phase 2 study of palovarotene for the treatment of fibrodysplasia ossificans progressiva (FOP).

26 Aug 2015

Chrono obtains second Fast Track SBIR grant award from NCI to support development of smoking cessation therapy

Chrono Therapeutics, a pioneer in digital drug therapy, today announced it has received a second Phase 1 and Phase 2 Fast Track Small Business Innovation Research (SBIR) grant award from the National Cancer Institute.

26 Aug 2015

Tocagen's Toca 511 & Toca FC receives FDA orphan drug designation for treatment of glioblastoma

Tocagen Inc., a clinical-stage immuno-oncology company, today announced that the U.S. Food and Drug Administration has granted orphan drug designation to the company's lead immuno-oncology product candidate, Toca 511 & Toca FC, for the treatment of glioblastoma.

26 Aug 2015

First patient enrolled in CSL Behring's rVIIa-FP Phase II/III study to treat patients with hemophilia A or B with inhibitors

CSL Behring announced today that the first patient has been enrolled in its Phase II/III clinical study evaluating the pharmacokinetics (PK), efficacy, and safety of the company's recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP) for on-demand treatment in patients with congenital hemophilia A or B who have developed an inhibitor to factor VIII or factor IX replacement therapy.

26 Aug 2015

Sequenom, UC San Diego Moores Cancer Center collaborate to explore utility of liquid biopsy assay

Sequenom, Inc., a life sciences company committed to enabling healthier lives through the development of innovative products and services, today announced that it has entered into a clinical research collaboration with the University of California, San Diego Moores Cancer Center.

26 Aug 2015

Medical Condition News

Study of genetic risk factors of IBD in African-Americans published in Gastroenterology journal

Longer-lasting colonoscopies associated with lower cancer rates

Inpatient palliative care visits associated with improved quality of life for patients with heart failure

UH research points to promising target in treatment of pancreatic cancer

New research could potentially yield novel platform for cancer vaccines

Persistent leukemia-associated genetic mutations linked to increased risk of relapse, reduced overall survival

Simple modification can increase effectiveness of emergency treatment for patients with supraventricular tachycardia

Study reveals how inflammation triggers colon cancer cells to metastasize

GW researchers find potential link between microbes in the throat and schizophrenia

Lingering cancer-related mutations linked to increased risk of relapse, poor survival in leukemia patients

Omega-3 supplements fail to slow cognitive decline in older persons, NIH clinical study shows

Mental visual imagery training may improve AM/EFT functioning in RR-MS patients

MorphoSys, Immatics partner to develop novel antibody-based therapies against multiple proprietary cancer antigens

Amgen to present data on Repatha (evolocumab) and observational studies at ESC Congress 2015

FDA, EMA accept filing applications for Boehringer Ingelheim's afatinib to treat patients with advanced SCC of the lung

Clementia expands enrollment to include children with FOP in ongoing Phase 2 clinical trial

Chrono obtains second Fast Track SBIR grant award from NCI to support development of smoking cessation therapy

Tocagen's Toca 511 & Toca FC receives FDA orphan drug designation for treatment of glioblastoma

First patient enrolled in CSL Behring's rVIIa-FP Phase II/III study to treat patients with hemophilia A or B with inhibitors

Sequenom, UC San Diego Moores Cancer Center collaborate to explore utility of liquid biopsy assay

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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