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Scientists find that collagen 'cross-links' can determine tumor's ability to grow and spread

When skyscrapers go up, contractors rely on an infrastructure of steel beams and braces. Some cancers grow the same way, using a biological matrix from which the tumor can thrive and spread.

10 Feb 2015

New model proposed for predicting outcomes more accurately in HPV-related throat cancer patients

Researchers at the Princess Margaret Cancer Centre are proposing a new model to enable doctors to predict outcomes more accurately for patients with throat cancers specifically caused by Human Papillomavirus (HPV).

10 Feb 2015

Radiation therapy more effective at preventing recurrence of ductal carcinoma in situ

In a surprising finding, a collaborative national clinical trials group (RTOG) including Dartmouth-Hitchcock's Alan Hartford, MD, PhD, discovered that radiation therapy in addition to chemotherapy was even more effective at preventing recurrence of ductal carcinoma in situ (DCIS) than previously thought.

10 Feb 2015

UB neurologist examines neurological disorders of U.S. presidents

Neurology and history may sound like two fields that don't often overlap, but they have, sometimes with extraordinary consequences, according to a University at Buffalo neurologist.

10 Feb 2015

Drugs designed to target NHE9 protein could help fight glioblastoma

Applying lessons learned from autism to brain cancer, researchers at The Johns Hopkins University have discovered why elevated levels of the protein NHE9 add to the lethality of the most common and aggressive form of brain cancer, glioblastoma. Their discovery suggests that drugs designed to target NHE9 could help to successfully fight the deadly disease.

10 Feb 2015

Discovery leads to new understanding of cancer metastasis

In a breakthrough in the understanding of how cancer spreads, researchers at the University of Virginia School of Medicine have identified a substance secreted by lung cancer cells that enables them to metastasize, beginning their deadly march to other sites in the body.

10 Feb 2015

Researchers discover inherited genetic variations associated with treatment-related hearing loss

St. Jude Children's Research Hospital investigators have discovered inherited genetic variations that are associated with rapid hearing loss in young cancer patients treated with the drug cisplatin. The research appears in the current online issue of the scientific journal Nature Genetics.

10 Feb 2015

Cancer researchers find important clues to why tumor cells become 'good' or 'bad'

For the first time, Keck Medicine of the University of Southern California cancer researchers have traced the origins of colorectal cancer cells, finding important clues to why tumor cells become "good" or "bad," with the potential of stopping them before they start.

10 Feb 2015

Scientists potentially discover new therapeutic targets to halt progression of tumor cells

Chronic inflammation is directly associated with several types of cancer, yet the reasons as to why this happens at a cellular level remain unclear. Now, an international team of scientists led by researchers at The Wistar Institute has identified a multistep process showing not only how these cancers develop but also potentially discovering new therapeutic targets that could halt the formation and progression of tumor cells.

10 Feb 2015

Combination therapies may overcome resistance to targeted cancer drugs

A protein called YAP, which drives the growth of organs during development and regulates their size in adulthood, plays a key role in the emergence of resistance to targeted cancer therapies, according to a new study led by UC San Francisco researchers.

10 Feb 2015

New study reveals eight highly specific physical signs associated with death in cancer patients

While the diagnosis of an impending death is always sad, it can be important for patients, families, and clinicians as they make decisions related to hospital discharge, hospice referral, and treatments. Now a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society, has revealed eight highly specific physical signs associated with death within three days in cancer patients.

10 Feb 2015

Study: Simple blood test could predict risk of developing dementia

Scientists at Rigshopitalet, Herlev Hospital and the University of Copenhagen identify a new biomarker that can predict the risk of developing dementia by way of a simple blood test. In the long term, this could mean better prevention and thus at least postponement of the illness and at best evading the development all together.

10 Feb 2015

FDA accepts NDA filing for Inspirion Delivery Technologies' investigational drug, MorphaBond ER

Inspirion Delivery Technologies, LLC, a specialty pharmaceutical company focused solely on the development of Abuse-Deterrent Formulations (ADFs) of opioid products, together with its financial partner Trygg Pharma Group, announced that the U.S. Food & Drug Administration has accepted for filing the New Drug Application ("NDA") submitted on November 21, 2014 for its investigational drug, MorphaBond ER, an extended-release (ER), abuse-deterrent formulation of morphine.

10 Feb 2015

‘Fear of bad news’ prevents 1 in 5 Brits from having a health check

There is no doubt that awaiting the results from medical tests can be an anxious time for anyone. However new research revealed today by HeartAge has revealed that when it comes to undertaking a general health check, almost 1 in 5 Brits appear to be opting for the “burying heads in the sand” approach, with`19% stating that concern over test results would prevent them from having a health check.

9 Feb 2015

Researchers document pathological progress of multiple sclerosis

The Centre for Brain Research at the MedUni Vienna is regarded as a world leader in researching the mechanisms involved with multiple sclerosis (MS). Now, in a paper published in the highly respected journal Lancet Neurology, an international team of researchers from Edinburgh, Cleveland and Vienna, under the leadership of Hans Lassmann, Head of the Department of Neuroimmunology at the MedUni Vienna, has for the first time documented the pathological progress of the disease from its early to late stage and also shown that inflammatory and neurodegenerative processes have a role to play.

9 Feb 2015

Oncolytics Biotech submits Orphan Drug Designation for high grade gliomas in pediatric patients

Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, NASDAQ: ONCY) today announced that it has submitted an application for Orphan Drug Designation to the U.S. Food and Drug Administration ("FDA") for REOLYSIN® for the treatment of high grade gliomas (HGG) in pediatric patients.

9 Feb 2015

New findings could pave way to develop drug therapies for necrosis-related diseases

Strokes, heart attacks and traumatic brain injuries are separate diseases with certain shared pathologies that achieve a common end - cell death and human injury due to hypoxia, or lack of oxygen.

9 Feb 2015

Chili peppers show promise as diet-based supplement

Don't go chomping on a handful of chili peppers just yet, but there may be help for hopeful dieters in those fiery little Native American fruits.

9 Feb 2015

Physical, psychosocial factors can significantly increase risk of low back pain

New research reveals the physical and psychosocial factors that significantly increase the risk of low back pain onset. In fact results published in Arthritis Care & Research, a journal of the American College of Rheumatology, show that being engaged in manual tasks involving awkward positions will increase the risk of low back pain by eight times. Those who are distracted during activities or fatigued also significantly increase their risk of acute low back pain.

9 Feb 2015

Discovery improves understanding of factors that trigger allergic asthma

When the mucosal surfaces in the lungs of healthy people come into contact with allergenic substances, so-called regulatory T cells also known as Treg cells, are activated. These are capable of actively preventing the development of allergies.

9 Feb 2015

Medical Condition News

Scientists find that collagen 'cross-links' can determine tumor's ability to grow and spread

New model proposed for predicting outcomes more accurately in HPV-related throat cancer patients

Radiation therapy more effective at preventing recurrence of ductal carcinoma in situ

UB neurologist examines neurological disorders of U.S. presidents

Drugs designed to target NHE9 protein could help fight glioblastoma

Discovery leads to new understanding of cancer metastasis

Researchers discover inherited genetic variations associated with treatment-related hearing loss

Cancer researchers find important clues to why tumor cells become 'good' or 'bad'

Scientists potentially discover new therapeutic targets to halt progression of tumor cells

Combination therapies may overcome resistance to targeted cancer drugs

New study reveals eight highly specific physical signs associated with death in cancer patients

Study: Simple blood test could predict risk of developing dementia

FDA accepts NDA filing for Inspirion Delivery Technologies' investigational drug, MorphaBond ER

‘Fear of bad news’ prevents 1 in 5 Brits from having a health check

Researchers document pathological progress of multiple sclerosis

Oncolytics Biotech submits Orphan Drug Designation for high grade gliomas in pediatric patients

New findings could pave way to develop drug therapies for necrosis-related diseases

Chili peppers show promise as diet-based supplement

Physical, psychosocial factors can significantly increase risk of low back pain

Discovery improves understanding of factors that trigger allergic asthma

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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