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FDA advisory committees to review Amgen's talimogene laherparepvec for metastatic melanoma treatment

Amgen announced today that the Cellular, Tissue and Gene Therapies Advisory Committee and the Oncologic Drugs Advisory Committee of the U.S. Food and Drug Administration will jointly review the Company's Biologics License Application (BLA) for talimogene laherparepvec.

11 Feb 2015

Cumberland initiates clinical development of Boxaban (ifetroban) oral capsule for AERD treatment

Cumberland Pharmaceuticals Inc. today announced an expansion of its pipeline with a new Phase II development program. The Company has initiated the clinical development of Boxaban (ifetroban) oral capsule for the treatment of aspirin-exacerbated respiratory disease (AERD).

11 Feb 2015

ADDF, Pfizer's CTI collaborate to advance development of new drugs for Alzheimer's disease

The Alzheimer's Drug Discovery Foundation and Pfizer's Centers for Therapeutic Innovation announced today a collaboration designed to advance the development of new small-molecule drugs for Alzheimer's disease and related dementias. As part of the first-of-its kind collaboration in Alzheimer's, the ADDF and CTI will jointly invest in translational research projects, with a focus on novel Alzheimer's drug targets.

11 Feb 2015

Movement Disorder Center at UC San Diego designated Center of Excellence in NPF's global network

The Movement Disorder Center at UC San Diego Health System has been designated the 41st Center of Excellence in the National Parkinson Foundation's global network. This competitive designation is the highest recognition offered by NPF to a Parkinson's specialty clinic and represents the consensus of leaders in the field that the multidisciplinary clinic at UC San Diego Health System is among the world's leading centers for Parkinson's research, outreach and care.

11 Feb 2015

First human clinical study of ChromaDex's NIAGEN nicotinamide riboside meets primary endpoint

ChromaDex Corp. announced today that the initial results of the first human clinical study for the company's NIAGEN nicotinamide riboside (NR) has met its primary endpoint.

11 Feb 2015

Researchers invent novel sock that can help prevent DVT, improve survival rates of patients

Patients who are bedridden or unable to move their legs are often at risk of developing Deep Vein Thrombosis (DVT), a potentially life-threatening condition caused by blood clots forming along the lower extremity veins of the legs. A team of researchers from the National University of Singapore's Yong Loo Lin School of Medicine and Faculty of Engineering has invented a novel sock that can help prevent DVT and improve survival rates of patients.

11 Feb 2015

Researchers close to novel therapy to treat levodopa-induced dyskinesia

Involuntary dyskinetic movements induced by treatment with levodopa (L-dopa) are a common problem for people with Parkinson's disease. Now, however, researchers at Karolinska Institutet and Lund University in Sweden seem to be close to a novel therapy to this distressing side effect.

11 Feb 2015

Research finds that mtDNA can move from healthy cell to dysfunctional tumour cell

Ground-breaking research from Griffith University on the Gold Coast has some scientists wondering if the entire study of cellular biology needs to be adjusted.

11 Feb 2015

UT Southwestern leads researchers to establish National Center for Heavy Ion Radiation Therapy

UT Southwestern Medical Center is leading a Texas consortium of researchers to establish the country's first National Center for Heavy Ion Radiation Therapy that could provide clinical care and research using heavy particles for innovative new cancer treatments.

11 Feb 2015

Freiburg researchers identify novel approach to inhibit signalling processes in colorectal cancer cells

Colorectal carcinoma is the most frequent type of bowel cancer and the second most common tumour disease among men and women in Germany. So-called microsatellite stable colorectal cancer with mutations in the BRAF gene represents a particularly aggressive form.

11 Feb 2015

Blood pressure-lowering treatment lowers CVD, heart disease risks among type 2 diabetes patients

Blood pressure-lowering treatment among patients with type 2 diabetes is associated with a lower risk of cardiovascular disease (CVD) and heart disease events and improved mortality, according to a study in the February 10 issue of JAMA.

11 Feb 2015

New type of engineered insulin could improve treatment for diabetes patients

For patients with diabetes, insulin is critical to maintaining good health and normal blood-sugar levels. However, it's not an ideal solution because it can be difficult for patients to determine exactly how much insulin they need to prevent their blood sugar from swinging too high or too low.

11 Feb 2015

Study finds higher levels of malignant mesothelioma cases in southern Nevada

Malignant mesothelioma has been found at higher than expected levels in women and in individuals younger than 55 years old in the southern Nevada counties of Clark and Nye, likewise in the same region carcinogenic mineral fibers including actinolite asbestos, erionite, winchite, magnesioriebeckite and richterite were discovered.

11 Feb 2015

UM one step closer to developing potential drug for treating brain cancer

Promentis Pharmaceuticals, Inc. recently announced it will enter an exclusive agreement with UM to commercialize a discovery made by a team of UM faculty scientists that has the potential to treat brain cancer and possibly other disorders of the central nervous system.

11 Feb 2015

UNC researchers create new research tool to help crack the histone code

University of North Carolina scientists have created a new research tool, based on the fruit fly, to help crack the histone code. This research tool can be used to better understand the function of histone proteins, which play critical roles in the regulation of gene expression in animals and plants.

11 Feb 2015

Study shows link between low vitamin D levels in childhood and occurrence of atherosclerosis in adulthood

Low levels of 25-OH vitamin D in childhood were associated with subclinical atherosclerosis over 25 years later in adulthood, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

11 Feb 2015

IOM committee identifies five main symptoms to diagnose ME/CFS

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome -- commonly referred to as ME/CFS -- is a legitimate, serious, and complex systemic disease that frequently and dramatically limits the activities of affected individuals, says a new report from the Institute of Medicine.

11 Feb 2015

Study suggests that gastric bypass should be used with caution to treat extreme obesity

Based on five-year follow-up of patients in a randomized clinical trial, researchers have concluded that gastric bypass is the preferred treatment for extreme obesity. This is despite the fact that it is not as effective in reducing body weight as the so-called duodenal switch.

11 Feb 2015

Research findings could lead to new standard of care for soft tissue sarcomas

Using advanced imaging technology to more precisely target radiation beams to treat soft tissue cancers (sarcomas) in the extremities significantly reduces long term side effects without effecting survival rates, according to research results published online today in the Journal of Clinical Oncology.

11 Feb 2015

Creatine monohydrate fails to slow clinical progression of Parkinson's disease

Treatment with creatine monohydrate for at least 5 years for patients with early and treated Parkinson disease failed to slow clinical progression of the disease, compared with placebo, according to a study in the February 10 issue of JAMA.

11 Feb 2015

Medical Condition News

FDA advisory committees to review Amgen's talimogene laherparepvec for metastatic melanoma treatment

Cumberland initiates clinical development of Boxaban (ifetroban) oral capsule for AERD treatment

ADDF, Pfizer's CTI collaborate to advance development of new drugs for Alzheimer's disease

Movement Disorder Center at UC San Diego designated Center of Excellence in NPF's global network

First human clinical study of ChromaDex's NIAGEN nicotinamide riboside meets primary endpoint

Researchers invent novel sock that can help prevent DVT, improve survival rates of patients

Researchers close to novel therapy to treat levodopa-induced dyskinesia

Research finds that mtDNA can move from healthy cell to dysfunctional tumour cell

UT Southwestern leads researchers to establish National Center for Heavy Ion Radiation Therapy

Freiburg researchers identify novel approach to inhibit signalling processes in colorectal cancer cells

Blood pressure-lowering treatment lowers CVD, heart disease risks among type 2 diabetes patients

New type of engineered insulin could improve treatment for diabetes patients

Study finds higher levels of malignant mesothelioma cases in southern Nevada

UM one step closer to developing potential drug for treating brain cancer

UNC researchers create new research tool to help crack the histone code

Study shows link between low vitamin D levels in childhood and occurrence of atherosclerosis in adulthood

IOM committee identifies five main symptoms to diagnose ME/CFS

Study suggests that gastric bypass should be used with caution to treat extreme obesity

Research findings could lead to new standard of care for soft tissue sarcomas

Creatine monohydrate fails to slow clinical progression of Parkinson's disease

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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