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Study reveals key role of A20 protein in controlling inflammation in liver disease

Many individuals worldwide suffer from chronic liver disease (CLD), which poses significant concerns for its tendency to lead to hepatocellular carcinoma or liver failure. CLD is characterized by inflammation and fibrosis.

29 Aug 2024

Routine lipoprotein(a) testing recommended for all adults

Heart experts say that everyone should have their levels of lipoprotein (a) (Lp(a) measured routinely at least once in life, following research from one of the most populous EU countries, Poland, that shows how common high levels of Lp(a) are in the general population.

29 Aug 2024

Smoking cessation reduces major cardiovascular events by almost half, study finds

According to research presented today at ESC Congress 2024, patients with stable coronary artery disease who quit smoking at any timepoint after their diagnosis reduced their risk of a major event by almost 50%.

29 Aug 2024

Weekend sleep could lower heart disease risk by 20%

The demands of the working week, often influenced by school or work schedules, can lead to sleep disruption and deprivation.

29 Aug 2024

Study explores link between prostate cancer treatment and Alzheimer’s disease

Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer's disease, and whether it's the standard hormone therapy treatment or an overactive immune response that actually contributes to the problem.

29 Aug 2024

Understanding the mechanisms of cardiac fibrosis

The article explores the role of the m6A reader YTHDF1 in cardiac fibrosis, a condition characterized by the excessive accumulation of extracellular matrix proteins, leading to the stiffening of the heart and impaired function. Cardiac fibrosis is a common pathological process in various cardiovascular diseases, including hypertension, myocardial infarction, and heart failure.

29 Aug 2024

New insights into AD pathogenesis and treatment

The main text of the study details the experiments conducted to understand the role of IL-24 in AD-like conditions. It describes the methods used, including single-cell RNA sequencing, and the animal models employed to mimic AD. The findings indicate that MRSA infection leads to increased IL-24 in keratinocytes, which in turn heightens type 2 immune responses and worsens AD symptoms.

29 Aug 2024

Addressing HPV vaccination disparities in girls with mental health conditions

Girls with mental illness or neurodevelopmental conditions are less likely than their peers to be vaccinated with the HPV vaccine that protects against future cervical cancer. This is according to a new registry study from Karolinska Institutet in Sweden published in The Lancet Public Health.

29 Aug 2024

Nanodrug targeting miR-10b shows promise in treating metastatic breast cancer

A new research paper was published in Oncotarget's Volume 15 on August 26, 2024, entitled, "Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties."

29 Aug 2024

AI unveils secrets of protein stability

Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI. The research team used AlphaFold2 to explore how mutations affect protein stability - a crucial factor in ensuring proteins function correctly and do not cause diseases like Alzheimer's.

29 Aug 2024

COVID-19 linked to increased risk of hearing loss in young adults, study finds

Researchers in South Korea found that young adults who recovered from COVID-19 are at significantly higher risk of experiencing hearing loss and sudden sensorineural hearing loss compared to those who never had the virus.

28 Aug 2024

New system can spot genetic markers of autism in brain images with high accuracy

A multi-university research team co-led by University of Virginia engineering professor Gustavo K. Rohde has developed a system that can spot genetic markers of autism in brain images with 89 to 95% accuracy.

28 Aug 2024

Study reveals a new target for universal treatment for autoimmune diseases

More than two decades ago, a research team in the lab of David Hafler, a Yale researcher who at the time was at Harvard, discovered a type of T cell in humans that suppresses the immune system; they later found that these so-called regulatory T cells, when defective, are an underlying cause of autoimmune disease, specifically multiple sclerosis (MS).

28 Aug 2024

SGLT-2 inhibitors show potential in preventing dementia in diabetes patients

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes might prevent dementia, providing greater benefits with longer treatment, suggests a large study from Korea published by The BMJ today.

28 Aug 2024

Scientists discover key to activating natural killer cells against cancer

Scientists are on the verge of a cancer breakthrough after working out how the body's immune system targets cells devastated by the disease.

28 Aug 2024

Study reveals misconceptions among professionals assessing dyslexia

Misconceptions about dyslexia are held by professionals who assess children for the learning difficulty, according to a new study which calls for evidence-based standardized assessment procedures.

28 Aug 2024

Researchers identify key cellular interactions driving Alzheimer's and aging

An analysis of more than 1.6 million brain cells from older adults has captured the cellular changes that occur in the early stages of Alzheimer's disease, potentially revealing new routes for preventing the most common cause of dementia in older individuals.

28 Aug 2024

16 promising postdoctoral scientists awarded Damon Runyon Fellowships for cancer research

The Damon Runyon Cancer Research Foundation has named 16 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

28 Aug 2024

Myocarditis risks linked to COVID-19 vaccination explained

Study examined myocarditis risks linked to COVID-19 mRNA vaccination, COVID-19 infection, and other causes. It found increased myocarditis incidence after vaccination but significantly lower mortality and hospitalization rates compared to myocarditis from other causes.

28 Aug 2024

Study confirms the link between blood glucose levels and voice pitch in people with Type 2 diabetes

As part of its ongoing exploration of vocal biomarkers and the role they can play in enhancing health outcomes, Klick Labs published a new study in Scientific Reports today – confirming the link between blood glucose levels and voice pitch and opening the door to future advancements in non-invasive glucose monitoring for people living with Type 2 diabetes.

28 Aug 2024