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Eventual drug resistance prevents long-term cure in most patients with metastatic melanoma

A study by scientists in Manchester has shown how melanoma drugs can cause the cancer to progress once a patient has stopped responding to treatment.

3 Jun 2014

Vanda’s HETLIOZ MAA for Non-24-Hour Sleep-Wake Disorder accepted for evaluation by the EMA

Vanda Pharmaceuticals Inc. announced today that its Marketing Authorization Application (MAA) for oral HETLIOZ™ (tasimelteon) capsules has been accepted for evaluation by the European Medicines Agency (EMA) for the treatment of Non-24-Hour Sleep-Wake Disorder (Non-24).

3 Jun 2014

Obesity, overweight correlated with prevalence of H. pylori infection

The germ Helicobacter pylori is the cause of most stomach ulcers, but new research in Alimentary Pharmacology & Therapeutics suggests that treating the bacteria is linked to weight gain.

3 Jun 2014

Penn and Mayo Clinic researchers launch Seizure Detection Challenge

Researchers from Mayo Clinic and the University of Pennsylvania announce the launch of the Seizure Detection Challenge, an international competition inviting the best minds in "machine learning" to improve devices to track and treat epilepsy.

3 Jun 2014

New research on innovative immunotherapies for melanoma, cervical cancer presented at ASCO 2014

New research on innovative immunotherapies for advanced or high-risk melanoma and cervical cancer were presented today at the 50th Annual Meeting of the American Society of Clinical Oncology.

3 Jun 2014

Risk-based preventive measures lower frequency of postoperative blood clots

Surgery patients are much less likely to get a blood clot in the lower extremities or lungs if they receive preventive treatment based on their individual clotting risk, in addition to walking soon after the operation.

3 Jun 2014

Researchers examine health benefits of yoga for asthma sufferers

Yoga has long been promoted as a method for improving physical and mental well-being. And although yoga is often suggested to asthma sufferers to help alleviate symptoms, a new study found little evidence that yoga will improve symptoms.

3 Jun 2014

Avastin and cetuximab extend life of patients with KRAS wild-type advanced bowel cancer

CALGB 80405, a large, independent, phase III study, designed to assess the superiority in overall survival (OS) of cetuximab over Avastin (bevacizumab) when combined with either FOLFOX or FOLFIRI chemotherapy in people with previously untreated, KRAS wild-type advanced (metastatic) bowel cancer has failed to meet this primary endpoint.

3 Jun 2014

NYU Langone scientists identify promising treatment target for Alzheimer's disease

Scientists at NYU Langone Medical Center have identified a compound, called 2-PMAP, in animal studies that reduced by more than half levels of amyloid proteins in the brain associated with Alzheimer's disease.

3 Jun 2014

New investigational immunotherapy benefits people with advanced urothelial bladder cancer

A new investigational immunotherapy MPDL3280A has been shown to shrink tumours in 43% of people (13/30) who had previously been treated for advanced urothelial bladder cancer (UBC) with a specific type of tumour (PD-L1 positive).

3 Jun 2014

Compliance with CPAP therapy may help prevent cardiovascular complications

A new study suggests that continuous positive airway pressure (CPAP) therapy rapidly improves blood pressure and arterial tone in adults with obstructive sleep apnea (OSA).

3 Jun 2014

Variations in BRCA2 and CHEK2 genes can increase lung cancer risk, study finds

New research confirms a vulnerability to lung cancer can be inherited and implicates the BRCA2 gene as harboring one of the involved genetic mutations.

3 Jun 2014

MRI-guided SLAH procedure provides safe, effective alternative to surgery

For patients with mesial temporal lobe epilepsy (MTLE) that can't be controlled by medications, a minimally invasive laser procedure performed under MRI guidance provides a safe and effective alternative to surgery, suggests a study in the June issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

3 Jun 2014

Hypnosis has positive impact on the quality of sleep

Sleeping well is a crucial factor contributing to our physical and mental restoration. SWS in particular has a positive impact for instance on memory and the functioning of the immune system. During periods of SWS, growth hormones are secreted, cell repair is promoted and the defence system is stimulated. If you feel sick or have had a hard working day, you often simply want to get some good, deep sleep. A wish that you can't influence through your own will - so the widely held preconception.

3 Jun 2014

New discovery may shed light on how common cold triggers asthma attacks

Cold season may be just behind us, but a new discovery may shed light on how this common condition triggers asthma attacks. In a new research report published in the June 2014 issue of the Journal of Leukocyte Biology, researchers show that in individuals with asthma, statins significantly reduce the in vitro inflammatory response of human monocytes to rhinovirus (RV), the cause of the common cold.

3 Jun 2014

Social integration impacts pulmonary function in elderly people

It is well established that being involved in more social roles, such as being married, having close friends, close family members, and belonging to social and religious groups, leads to better mental and physical health. However, why social integration - the total number of social roles in which a person participates - influences health and longevity has not been clear.

3 Jun 2014

Study uncovers marijuana's potential to treat autoimmune diseases

A team of University of South Carolina researchers led by Mitzi Nagarkatti, Prakash Nagarkatti and Xiaoming Yang have discovered a novel pathway through which marijuana can suppress the body's immune functions. Their research has been published online in the Journal of Biological Chemistry.

3 Jun 2014

Jazz Pharmaceuticals' JZP-110 improves symptoms of EDS in adults with narcolepsy

Jazz Pharmaceuticals plc today presented data from the Phase 2b study evaluating JZP-110 (formerly known as ADX-N05) as a potential new treatment for the symptoms of excessive daytime sleepiness (EDS) in adults with narcolepsy.

3 Jun 2014

P2Y12 and blood clotting: an interview with Dr. Jacobson, NIH

We already understand the many steps involved in blood clotting in great mechanistic detail. The process of blood vessels closing off in response to injury is necessary for preserving life, but blood platelets that are over-active, or activated inappropriately because of unstable plaque, can lead to heart attacks and strokes.

3 Jun 2014

Cerenis’ SAMBA and MODE Phase II Studies Meet Primary Endpoints for Treatment of FPHA, HoFH

Cerenis Therapeutics, the biopharmaceutical company, today announced that two of its Phase II studies, SAMBA and MODE (Modifying Orphan Disease Evaluation), with CER-001, an engineered human apoA-I-containing pre-β HDL mimetic, met their primary clinical endpoints in patients with Familial Primary Hypoalphalipoproteinemia (FPHA) and Homozygous Familial Hypercholesterolemia (HoFH), respectively.

2 Jun 2014

Medical Condition News

Eventual drug resistance prevents long-term cure in most patients with metastatic melanoma

Vanda’s HETLIOZ MAA for Non-24-Hour Sleep-Wake Disorder accepted for evaluation by the EMA

Obesity, overweight correlated with prevalence of H. pylori infection

Penn and Mayo Clinic researchers launch Seizure Detection Challenge

New research on innovative immunotherapies for melanoma, cervical cancer presented at ASCO 2014

Risk-based preventive measures lower frequency of postoperative blood clots

Researchers examine health benefits of yoga for asthma sufferers

Avastin and cetuximab extend life of patients with KRAS wild-type advanced bowel cancer

NYU Langone scientists identify promising treatment target for Alzheimer's disease

New investigational immunotherapy benefits people with advanced urothelial bladder cancer

Compliance with CPAP therapy may help prevent cardiovascular complications

Variations in BRCA2 and CHEK2 genes can increase lung cancer risk, study finds

MRI-guided SLAH procedure provides safe, effective alternative to surgery

Hypnosis has positive impact on the quality of sleep

New discovery may shed light on how common cold triggers asthma attacks

Social integration impacts pulmonary function in elderly people

Study uncovers marijuana's potential to treat autoimmune diseases

Jazz Pharmaceuticals' JZP-110 improves symptoms of EDS in adults with narcolepsy

P2Y12 and blood clotting: an interview with Dr. Jacobson, NIH

Cerenis’ SAMBA and MODE Phase II Studies Meet Primary Endpoints for Treatment of FPHA, HoFH

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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