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Layers of skin that form first line of defence in body's fight against infection reveal secret

The layers of skin that form the first line of defence in the body's fight against infection have revealed a unanticipated secret.

19 Nov 2013

TOPCAT trial results of spironolactone presented at AHA Scientific Sessions

A late-breaking clinical trial, known as the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist trial, to be presented at the American Heart Association Scientific Sessions, November 18, 2013, demonstrates that spironolactone did not reduce the primary outcome of cardiovascular death, heart failure hospitalization, nor surviving a cardiac arrest in patients with heart failure and preserved ejection fraction (pump function). However, spironolactone did reduce the major burden faced by these patients-the risk of repeated hospitalizations for heart failure.

19 Nov 2013

Two drugs tested in larger trial fail to improve kidney function in patients with acute heart failure

Two drugs tested in a larger trial did not improve kidney function in acute heart failure patients, contrary to results of smaller studies. The results were presented today at the American Heart Association's Scientific Sessions 2013 in Dallas and simultaneously published in the Journal of the American Medical Association. Previous smaller studies showed that low-dose dopamine or low-dose nesiritide could improve kidney function and reduce fluid overload that is often present in hospitalized acute heart failure patients by increasing urine production.

19 Nov 2013

More than half of teenagers with psychiatric disorders receive no treatment of any sort

More than half of adolescents with psychiatric disorders receive no treatment of any sort, says a new study by E. Jane Costello, a Duke University professor of psychology and epidemiology and associate director of the Duke Center for Child and Family Policy. When treatment does occur, the providers are rarely mental health specialists, says the study, which was based on a survey of more than 10,000 American teenagers.

19 Nov 2013

Cranberries' unique bioactive compounds improve heart health and temper inflammation

Cranberries are more than a holiday favorite, given their remarkable nutritional and health benefits. A new research review published in the international journal Advances in Nutrition provides reasons why these tiny berries can be front and center and not just a side dish. The review authors conclude that cranberries provide unique bioactive compounds that may help reduce the incidence of certain infections, improve heart health and temper inflammation.

19 Nov 2013

Study finds tracking workout, diet habits via text messages could improve healthy routines

If the idea of keeping a food and exercise diary keeps you from joining a weight-loss program, there may be a better way.

19 Nov 2013

Adolescents who drink alone have more alcohol problems

Most teenagers who drink alcohol do so with their friends in social settings, but a new study by researchers at Carnegie Mellon University and the University of Pittsburgh reveals that a significant number of adolescents consume alcohol while they are alone.

19 Nov 2013

Treating traumatic brain-injured patients with anticoagulant decreases risk of dangerous clots

Researchers from the University of Missouri School of Medicine have found that a new protocol that uses preventive blood-thinning medication in the treatment of patients with traumatic brain injuries reduces the risk of patients developing life-threatening blood clots without increasing the risk of bleeding inside the brain.

19 Nov 2013

Manipulating PRH protein can help prevent cancer cells from unnecessary migration

Understanding how and why cancer cells move away from their original location is important to find ways to stop the spread of the disease. New findings, published in the Nature journal Oncogene, reveal how a protein, called 'PRH', is normally able to prevent cells from unnecessary migration. It is likely that this protein is less effective in cancer cells allowing the cells to venture away.

19 Nov 2013

Scientists use new method to draw map of cancer's family tree

A new method to take the DNA fingerprint of individual cancer cells is uncovering the true extent of cancer's genetic diversity, new research reveals.

19 Nov 2013

Patients better adhere to medication regimens following hospitalization for acute coronary syndrome

Patients better adhered to their medication regimens in the year following hospitalization for acute coronary syndrome when they were part of a program that included personalized attention from a pharmacist compared with usual care, according to a study by P. Michael Ho, M.D., Ph.D., of the Denver VA Medical Center, and colleagues.

19 Nov 2013

National Multiple Sclerosis Society awards grant to MSDF to focus on progressive MS

The National Multiple Sclerosis Society is partnering with the Accelerated Cure Project's Multiple Sclerosis Discovery Forum - an interactive online community and information portal for researchers and clinicians - to develop resources and content focusing on progressive MS. Promoting engagement by the research community on issues in progressive MS is one aspect of a multifaceted approach to increasing progress in this underexplored area of research.

19 Nov 2013

Researchers find that caspase-2 gene plays important role in suppressing blood cell cancer

Adelaide researchers have found that a specific gene plays an important role in suppressing lymphoma, a type of blood cell cancer.

19 Nov 2013

Extract from bitter melon may have therapeutic qualities to treat head and neck cancer

Extract taken from an Asian vegetable may have therapeutic qualities to treat head and neck cancer, a Saint Louis University researcher has found.

19 Nov 2013

Vismodegib drug does not offer added benefits for patients with BCC

The drug vismodegib (trade name: Erivedge) is approved for the treatment of patients with two forms of basal cell carcinoma: symptomatic metastatic BCC and locally advanced BCC inappropriate for surgery or radiotherapy.

19 Nov 2013

Research findings offer new hope for millions of traumatic brain injury patients

Every year, nearly two million people in the United States suffer traumatic brain injury (TBI), the leading cause of brain damage and permanent disabilities that include motor dysfunction, psychological disorders, and memory loss. Current rehabilitation programs help patients but often achieve limited success.

19 Nov 2013

Young adults who had childhood cancer more likely to be frail than their peers

Young adults who survived childhood cancer are more likely than their peers to be frail, according to a St. Jude Children's Research Hospital study, which reported the condition is more common among female survivors than women decades older. The research appears in the November 18 online edition of the Journal of Clinical Oncology.

18 Nov 2013

BIDMC pilot study shows promise for age-related cognitive disorders

It's well known that the brains of meditators change, but it's not entirely clear what those changes mean or how the changes might benefit the meditator. A new pilot study led by researchers at Beth Israel Deaconess Medical Center suggests that the brain changes associated with meditation and stress reduction may play an important role in slowing the progression of age-related cognitive disorders like Alzheimer's disease and other dementias.

18 Nov 2013

Paragonix files second 510(k) with FDA for Sherpa Pak Cardiac Transport System

Paragonix Technologies, Inc. today announced that it has successfully completed filing of a second Pre-Marketing Notification Application (510(k)) with the US Food and Drug Administration (FDA) for its Paragonix Sherpa Pak Cardiac Transport System(CTS).

18 Nov 2013

Kiadis reports successful Phase II enrollment for CR-AIR-007 ATIR blood cancer treatment study

Kiadis Pharma B.V., a clinical stage biopharmaceutical company developing treatments for blood cancers, today announces the successful Phase II enrollment of approximately ten patients of whom the majority have already been transplanted and received ATIR™. Kiadis Pharma's lead program, ATIR™, is a cell-based product designed to enable stem cell transplantations from partially mismatched (haploidentical) family donors for blood cancer patients who do not have a standard of care stem cell donor available. Topline data from the trial (CR-AIR-007) is expected in the first half of 2014.

18 Nov 2013

Medical Condition News

Layers of skin that form first line of defence in body's fight against infection reveal secret

TOPCAT trial results of spironolactone presented at AHA Scientific Sessions

Two drugs tested in larger trial fail to improve kidney function in patients with acute heart failure

More than half of teenagers with psychiatric disorders receive no treatment of any sort

Cranberries' unique bioactive compounds improve heart health and temper inflammation

Study finds tracking workout, diet habits via text messages could improve healthy routines

Adolescents who drink alone have more alcohol problems

Treating traumatic brain-injured patients with anticoagulant decreases risk of dangerous clots

Manipulating PRH protein can help prevent cancer cells from unnecessary migration

Scientists use new method to draw map of cancer's family tree

Patients better adhere to medication regimens following hospitalization for acute coronary syndrome

National Multiple Sclerosis Society awards grant to MSDF to focus on progressive MS

Researchers find that caspase-2 gene plays important role in suppressing blood cell cancer

Extract from bitter melon may have therapeutic qualities to treat head and neck cancer

Vismodegib drug does not offer added benefits for patients with BCC

Research findings offer new hope for millions of traumatic brain injury patients

Young adults who had childhood cancer more likely to be frail than their peers

BIDMC pilot study shows promise for age-related cognitive disorders

Paragonix files second 510(k) with FDA for Sherpa Pak Cardiac Transport System

Kiadis reports successful Phase II enrollment for CR-AIR-007 ATIR blood cancer treatment study

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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