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Takeda terminates development activities for fasiglifam (TAK-875)

Takeda Pharmaceutical Company Limited (Takeda) announced today that it has decided voluntarily to terminate the development activities for fasiglifam (TAK-875), an investigational treatment for type 2 diabetes, due to concerns about liver safety.

27 Dec 2013

A valuable guide for diabetic patients

McCord Research, Inc., founded by Darlene McCord, Ph.D., FAPWCA, has produced a valuable guide to help people with diabetes take care of their feet for a lifetime. Dr. McCord has over 30 years of experience in the skin and wound care industry. Ten years ago she also created the most successful skin and wound care product line in North America.

27 Dec 2013

Researchers study health consequences of RTE proliferation that occurs in aging tissues

The genomes of organisms from humans to corn are replete with "parasitic" strands of DNA that, when not suppressed, copy themselves and spread throughout the genome, potentially affecting health. Earlier this year Brown University researchers found that these "retrotransposable elements" were increasingly able to break free of the genome's control in cultures of human cells.

27 Dec 2013

Scientists analyze nutrition and physical activity behavior that could prevent risk of diabetes

"I'm going to do more sport in the new year." Hardly any resolution is made more frequently than this one after the calorie-filled Christmas holidays - and hardly one that is broken as frequently. A team headed by Prof. Wolfgang Schlicht from the Institute for Sport and Movement Science at the University of Stuttgart are investigating behaviour techniques in the framework of the project "PREVIEW" with which the physical activity behaviour can be changed in the long term. T

27 Dec 2013

FNIH Biomarkers Consortium announces initial results of I-SPY 2 trial for breast cancer

The I-SPY 2 TRIAL, a randomized phase II clinical trial for breast cancer launched through a unique partnership with the Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium and sponsored by QuantumLeap Healthcare Collaborative has graduated the first two drugs from its innovative, multidrug standing platform trial.

27 Dec 2013

Cells' adaptations to low oxygen conditions inside tumors promote breast cancer's spread

Biologists at The Johns Hopkins University have discovered that low oxygen conditions, which often persist inside tumors, are sufficient to initiate a molecular chain of events that transforms breast cancer cells from being rigid and stationery to mobile and invasive.

27 Dec 2013

Older adults with low back pain are interested in receiving co-managed care, shows study

The Foundation for Chiropractic Progress (F4CP), a not-for-profit organization dedicated to raising awareness about the value of chiropractic care, promotes the findings of a new study, "Perspectives of older adults on co-management of low back pain by doctors of chiropractic and family medicine physicians: a focus group study" (BMC Complementary & Alternative Medicine, 9.16.2013).

27 Dec 2013

EMA accepts Otsuka's marketing authorisation application for tolvaptan for treatment of ADPKD

Otsuka Pharmaceutical Co., Ltd. announced today that the European Medicines Agency (EMA) has accepted the submission of a marketing authorisation application (MAA) for the potential approval of tolvaptan for the treatment of autosomal dominant polycystic kidney disease (ADPKD).

27 Dec 2013

Oral ingestion of inosine compound raises urate levels, shows Parkinson's study

New findings published in JAMA Neurology from research into a potentially protective therapy for Parkinson's disease (PD) show that with medical supervision, urate levels may safely be raised while mitigating risk of complications such as gout.

27 Dec 2013

SLU professor offers 6 tips to relieve stress

Have you made a New Year's resolution yet? Consider this - as we inch closer to the New Year, William Manard, M.D., assistant professor in the department of family and community medicine at Saint Louis University suggests making a broad lifestyle change by better managing your emotional health.

27 Dec 2013

Research: Neuropeptides may serve as index for evaluating early peripheral nerve injury

Substance P and calcitonin gene-related peptide are the main neuropeptides in peripheral nerve ganglia, which can anterogradely transmit nociceptive information to the central nervous system.

27 Dec 2013

Stem cell-based gene therapy shows long-term outcomes for treatment of genetic skin diseases

Stem cell-based gene therapy holds promise for the treatment of devastating genetic skin diseases, but the long-term clinical outcomes of this approach have been unclear.

27 Dec 2013

Scientists find inhibiting action of BRD4 protein may eradicate rare type of soft-tissue cancer

A deadly, rare type of soft-tissue cancer may be completely eradicated simply by inhibiting a key protein involved in its growth, UT Southwestern Medical Center researchers report.

27 Dec 2013

Three foods can help prevent Alzheimer's disease

The number of Americans with Alzheimer's is projected to triple by 2050. While there isn't a cure for Alzheimer's, certain lifestyle changes can help prevent cognitive decline.

27 Dec 2013

Experts to share insights on the integration of science, psychotherapy and spirituality

Neuroscience is the new buzzword in the world of psychotherapy, yet distinguishing between true innovation and mere speculation can be difficult. In a new program at the 2014 iaedp Symposium in St. Petersburg, Florida (February 26-March 2), keynote speakers, Carolyn Costin, MFt, MA, MEd, CEDS and Joan Borysenko, PhD, will share their insights on the integration of science, psychotherapy and spirituality.

27 Dec 2013

Concussion involving momentary loss of consciousness may be related to buildup of Alzheimer's

A new study suggests that a history of concussion involving at least a momentary loss of consciousness may be related to the buildup of Alzheimer's-associated plaques in the brain.

27 Dec 2013

Kinect-based virtual reality training boosts functional recovery of upper limbs after subacute stroke

The Kinect-based virtual reality system for the Xbox 360 enables users to control and interact with the game console without the need to touch a game controller, and provides rehabilitation training for stroke patients with lower limb dysfunctions.

27 Dec 2013

Magnetic nanoparticles-based method uses saliva to screen DNA polymorphism in stroke patients

C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene is a risk factor for stroke. Studies have report a higher C677T homozygosity frequency in Chinese than in Europeans. Usually, the detection of genetic diseases is rather complicated on a large scale owing to the invasive sampling and a cumbersome DNA extraction process.

27 Dec 2013

Surgery offers better survival, functional outcomes than chemotherapy for patients with tongue cancer

Patients with tongue cancer who started their treatment with a course of chemotherapy fared significantly worse than patients who received surgery first, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

27 Dec 2013

THRIL could be novel biomarker for immune activation, potential target for inflammatory diseases

Sanford-Burnham Medical Research Institute scientists have discovered a new molecule that forms when certain white blood cells-macrophages-are stimulated in response to pathogens.

27 Dec 2013

Medical Condition News

Takeda terminates development activities for fasiglifam (TAK-875)

A valuable guide for diabetic patients

Researchers study health consequences of RTE proliferation that occurs in aging tissues

Scientists analyze nutrition and physical activity behavior that could prevent risk of diabetes

FNIH Biomarkers Consortium announces initial results of I-SPY 2 trial for breast cancer

Cells' adaptations to low oxygen conditions inside tumors promote breast cancer's spread

Older adults with low back pain are interested in receiving co-managed care, shows study

EMA accepts Otsuka's marketing authorisation application for tolvaptan for treatment of ADPKD

Oral ingestion of inosine compound raises urate levels, shows Parkinson's study

SLU professor offers 6 tips to relieve stress

Research: Neuropeptides may serve as index for evaluating early peripheral nerve injury

Stem cell-based gene therapy shows long-term outcomes for treatment of genetic skin diseases

Scientists find inhibiting action of BRD4 protein may eradicate rare type of soft-tissue cancer

Three foods can help prevent Alzheimer's disease

Experts to share insights on the integration of science, psychotherapy and spirituality

Concussion involving momentary loss of consciousness may be related to buildup of Alzheimer's

Kinect-based virtual reality training boosts functional recovery of upper limbs after subacute stroke

Magnetic nanoparticles-based method uses saliva to screen DNA polymorphism in stroke patients

Surgery offers better survival, functional outcomes than chemotherapy for patients with tongue cancer

THRIL could be novel biomarker for immune activation, potential target for inflammatory diseases

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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