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Genetic investigation of tribes may explain why East Asians have lower skin cancer rates

Genetic investigation of a Malaysian tribe may tell scientists why East Asians have light skin but lower skin cancer rates than Europeans, according to a team of international researchers. Understanding the differences could lead to a better way to protect people from skin cancer.

29 Aug 2012

New treatment for severe dry eye is now available at U-M’s Kellogg

A new treatment available at the University of Michigan Kellogg Eye Center—prosthetic replacement of the ocular surface ecosystem or PROSE—provides relief to patients who suffer from severe dry eye, often the result of cancer or complex corneal disease.

29 Aug 2012

FISH assay identifies only few lung cancer patients who could benefit from crizotinib

Break apart a couple worm-like chromosomes and they may reconnect with mismatched tips and tails - such is the case of the EML4-ALK fusion gene that creates 2-7 percent of lung cancers. Almost exactly a year ago, the FDA approved the drug crizotinib to treat these ALK+ lung cancer patients, who were likely never smokers. Informed doctors use the test called a FISH assay to check for the EML4-ALK fusion gene, and then if the test is positive, ALK+ patients benefit greatly from crizotinib.

29 Aug 2012

Deep-brain stimulation may stop uncontrollable shaking in patients with Parkinson's

Deep-brain stimulation (DBS) may stop uncontrollable shaking in patients with Parkinson's disease and essential tremor by imposing its own rhythm on the brain, according to two studies published recently by University of Alabama at Birmingham researchers in the journal Movement Disorders.

29 Aug 2012

Novelos expects to submit CLR1502 IND with FDA for non-invasive tumor imaging

Novelos Therapeutics, Inc., a pharmaceutical company developing novel drugs for the treatment and diagnosis of cancer, today announced that it is developing CLR1502 (GLOW2), a preclinical cancer-targeted optical imaging agent for intraoperative tumor margin illumination and non-invasive tumor imaging.

29 Aug 2012

Study to investigate how breast cancer patients might benefit from exercise

Researchers in Edmonton and Calgary want to recruit 1,500 breast cancer patients over the next decade to find out how exercise and fitness affects cancer survival and recovery.

29 Aug 2012

New Wilderness Medical Society guidelines for prevention and treatment of lightning injuries

About 24,000 people are killed by lightning every year, with about 10 times as many people injured. The Wilderness Medical Society has issued important new practice guidelines for precautions that can lower the likelihood of being killed or injured and recommendations for effective medical treatments post-strike.

29 Aug 2012

Acute Cardiovascular Care Association of ESC launches today

ACCA was previously the ESC Working Group on Acute Cardiac Care. Today it becomes one of six ESC Associations, whose presidents are invited to ESC Board meetings. "It will be easier to inform the ESC Board about the activities of the association," said Professor Christiaan Vrints (Belgium), outgoing chairman of the Working Group on Acute Cardiac Care. "We will also have a bigger impact on the policies and the development of the ESC as an organisation."

29 Aug 2012

FFR-guided PCI plus medical therapy reduce need for urgent revascularization in CAD patients

Patients with stable coronary artery disease (CAD) had a lower need for urgent revascularisation when receiving fractional flow reserve (FFR)-guided PCI plus the best available medical therapy (MT) than when receiving MT alone. The results, from a final analysis of the FAME 2 trial, were presented today during a Hot Line session of ESC Congress 2012 in Munich.

29 Aug 2012

Study explains strategies that work against long-term weight loss in post-menopausal women

Many people can drop pounds quickly in the early phases of a diet, but studies have found that it is difficult to keep the weight off in the long term. For post-menopausal women, natural declines in energy expenditure could make long-term weight loss even more challenging. A new study finds that in post-menopausal women, some behaviors that are related to weight loss in the short term are not effective or sustainable for the long term. Interventions targeting these behaviors could improve long-term obesity treatment outcomes.

29 Aug 2012

BMBF awards 16M€ to support German epigenome program initiative

The German Ministry for Research and Education (BMBF) will support the German epigenome program initiative "DEEP" with a budget of 16M€ over 5 years.

29 Aug 2012

Scientists decode signals that boost the burning of fat

The numbers of obese people are climbing steeply all over the world - with obvious major consequences for their health. Due to excess food intake and a lack of physical activity, but also due to genetic factors, the risk for overweight people dying from diseases like coronary heart disease, diabetes und atherosclerosis increases.

29 Aug 2012

Risk of stroke after myocardial infarction seems to decrease with improvements in coronary care

The analysis of data from two Swedish registries was presented by Dr Anders Ulvenstam, and suggests that the reduction is due to improvements in AMI care.

29 Aug 2012

Esperance completes EP 100 and paclitaxel Phase 2 combination trial on advanced ovarian cancer

Esperance Pharmaceuticals today announced the completion of the run-in cohort of its Phase 2, randomized, multi‐center trial of EP‑100 in combination with paclitaxel for patients with advanced ovarian cancer. EP‐100 is a targeted membrane‐disrupting peptide (tMDP) designed to seek and destroy cancer cells that overexpress luteinizing hormone releasing hormone (LHRH) receptors on their surfaces.

29 Aug 2012

Catheter ablation for Afib is safe and suppresses arrhythmia recurrences

Catheter ablation for atrial fibrillation (Afib) is safe and suppresses arrhythmia recurrences in 74% of patients after a single procedure, according to results from the one-year follow-up of the Atrial Fibrillation Ablation Pilot Study, the first European registry to evaluate the real-life epidemiology of catheter ablation for AFib.

29 Aug 2012

Ultra-fast 320-detector CT scanner can accurately diagnose arterial blockages

An ultra-fast, 320-detector computed tomography (CT) scanner can accurately sort out which people with chest pain need - or don't need - an invasive procedure such as cardiac angioplasty or bypass surgery to restore blood flow to the heart, according to an international study. Results of the study, which involved 381 patients at 16 hospitals in eight countries, are scheduled to be presented at the European Society of Cardiology Congress in Munich, Germany, on August 28.

29 Aug 2012

Scientists identify genes that underlie growth of primitive leukemia stem cells

University of Rochester Medical Center scientists believe they are the first to identify genes that underlie the growth of primitive leukemia stem cells, and then to use the new genetic signature to identify currently available drugs that selectively target the rogue cells.

29 Aug 2012

Top-line results from Rexahn’s Archexin Phase II study on metastatic pancreatic cancer

Rexahn Pharmaceuticals, Inc., a clinical stage biopharmaceutical company focused on developing multi-indication therapeutics in oncology and CNS, today announced top-line results from a Phase II clinical study of Archexin, its clinical-stage oncology drug candidate.

29 Aug 2012

Addition of CTP to CT angiography allows clinicians to identify flow-limiting coronary artery disease

A non-invasive imaging strategy which integrates non-invasive CT angiography (CTA) and CT myocardial perfusion imaging (CTP) has robust diagnostic accuracy for identifying patients with flow-limiting coronary artery disease in need of myocardial revascularisation, according to results of the CORE320 study presented here today by Dr Joao AC Lima from Johns Hopkins Hospital, Baltimore, USA.

29 Aug 2012

St. Jude’s EnligHTN renal denervation system safe and effective in treating resistant hypertension

St. Jude Medical, Inc., a global medical device company, today announced that interim data demonstrated the company's EnligHTN renal denervation system is safe and effective for the treatment of resistant hypertension.

29 Aug 2012

Medical Condition News

Genetic investigation of tribes may explain why East Asians have lower skin cancer rates

New treatment for severe dry eye is now available at U-M’s Kellogg

FISH assay identifies only few lung cancer patients who could benefit from crizotinib

Deep-brain stimulation may stop uncontrollable shaking in patients with Parkinson's

Novelos expects to submit CLR1502 IND with FDA for non-invasive tumor imaging

Study to investigate how breast cancer patients might benefit from exercise

New Wilderness Medical Society guidelines for prevention and treatment of lightning injuries

Acute Cardiovascular Care Association of ESC launches today

FFR-guided PCI plus medical therapy reduce need for urgent revascularization in CAD patients

Study explains strategies that work against long-term weight loss in post-menopausal women

BMBF awards 16M€ to support German epigenome program initiative

Scientists decode signals that boost the burning of fat

Risk of stroke after myocardial infarction seems to decrease with improvements in coronary care

Esperance completes EP 100 and paclitaxel Phase 2 combination trial on advanced ovarian cancer

Catheter ablation for Afib is safe and suppresses arrhythmia recurrences

Ultra-fast 320-detector CT scanner can accurately diagnose arterial blockages

Scientists identify genes that underlie growth of primitive leukemia stem cells

Top-line results from Rexahn’s Archexin Phase II study on metastatic pancreatic cancer

Addition of CTP to CT angiography allows clinicians to identify flow-limiting coronary artery disease

St. Jude’s EnligHTN renal denervation system safe and effective in treating resistant hypertension

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

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