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Deficiency in SNX27 explains learning impairment in Down's syndrome

Scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) have identified the precise role of the protein, SNX27, in the pathway leading to memory and learning impairment.

20 Feb 2014

Medications to lower blood pressure after stroke does not reduce likelihood of death

A major study has found that giving stroke patients medications to lower their blood pressure during the first 48 hours after a stroke does not reduce the likelihood of death or major disability.

20 Feb 2014

Antidepressant medication shows potential in treating symptoms of agitation that occur with AD

An antidepressant medication has shown potential in treating symptoms of agitation that occur with Alzheimer's disease and in alleviating caregivers' stress, according to a multi-site U.S.- Canada study.

20 Feb 2014

New information on pathogenesis of feeding and swallowing difficulties in kids with autism

Collaborative research out of the George Washington University (GW) reveals new information on the pathogenesis of feeding and swallowing difficulties often found in children with neurodevelopmental disorders, including autism and intellectual disability.

20 Feb 2014

Cystinosis Research Foundation granted $2.15M in 2013 to researchers investigating cure for cystinosis

The Cystinosis Research Foundation awarded $2,153,048 in 2013 to researchers investigating better treatments and a cure for cystinosis, a rare metabolic and genetic disease that afflicts about 500 children and young adults in the United States and 2,000 worldwide.

19 Feb 2014

Indacaterol/glycopyrronium drug combination offers added benefit for adults with COPD

The drug combination indacaterol/glycopyrronium (trade name: Ultibro Breezhaler, Xoterna Breezhaler) has been approved since September 2013 for adults with chronic obstructive pulmonary disease (COPD).

19 Feb 2014

Too much sedentary time linked to major disability after 60

If you're 60 and older, every additional hour a day you spend sitting is linked to doubling the risk of being disabled -- regardless of how much moderate exercise you get, reports a new Northwestern Medicine- study.

19 Feb 2014

Researchers explore possible link between metabolic defects and seizures

Researchers from the Franciscan University of Steubenville, Ohio are exploring a possible link between metabolic defects and seizures. They determined that diet could influence susceptibility to seizures, and they have identified a common diabetes drug that could be useful in treating disorders such as epilepsy.

19 Feb 2014

How do people become depressed? An interview with Anna Watters and Professor Lea Williams, University of Sydney

A clinical diagnosis of depression (i.e. major depressive disorder) is currently defined on the basis of reported symptoms.

19 Feb 2014

Young adults with high blood pressure often not prescribed medication

Primary care doctors are not quick to prescribe antihypertensive medication to young people even after an average of 20 months of high blood pressure. Young adults who are white, male, not on Medicaid and not frequent clinic visitors are especially less likely to receive medication. These are the results of a study by a research team at the University of Wisconsin School of Medicine and Public Health in the United States led by Heather Johnson.

19 Feb 2014

Omeros doses first patient in second Phase 2 clinical trial of OMS824

Omeros Corporation today announced dosing of the first patient in a second Phase 2 clinical trial of OMS824, the company's phosphodiesterase 10 (PDE10) inhibitor being developed for the treatment of schizophrenia, Huntington's disease (HD) and other cognitive disorders. The Phase 2 trial will evaluate the tolerability, safety, pharmacokinetics and performance on a battery of tests in patients with symptomatic HD.

19 Feb 2014

Physicians’ attitudes about obesity may affect patients’ success in losing weight

Overweight and obese people who feel their physicians are judgmental of their size are more likely to try to shed pounds but are less likely to succeed, according to results of a study by Johns Hopkins researchers.

19 Feb 2014

Researchers develop method for diagnosis and prognosis of cutaneous melanoma

UPV/EHU researchers have developed a method for the diagnosis and prognosis of cutaneous melanoma, the type of skin cancer with the highest mortality rate.This method will help not only in the more effective early detection of this cancer, but also in the development of more personalised treatments.

19 Feb 2014

UH Case Medical Center cardiologists perform TAVR procedure under twilight

University Hospitals Case Medical Center cardiologists Marco Costa, MD, and Dan Simon, MD, are among the first in the country to perform transaortic valve replacements (TAVR) while the patient is in a "twilight" sedation, awake and communicating with them during the procedure.

19 Feb 2014

Researchers examine impact of diet for preventing Alzheimer's dementia

A cocktail of ingredients containing omega-3 fatty acid found in fish oil is being tested in patients with mild cognitive impairment as a means to slow the progression of Alzheimer's dementia down

19 Feb 2014

Researchers reveal effectiveness of web-based weight-loss programs

Researchers from The Miriam Hospital have found that DietBet, a web-based commercial weight loss program that pairs financial incentives with social influence, delivers significant weight losses. The study and its findings have been published in the current issue of the open access publication JMIR Serious Games.

19 Feb 2014

Neuropsychological assessment efficiently tracks disease progression in memory clinic patients

Investigators at the University of Amsterdam, The Netherlands, have shown that progression of disease in memory clinic patients can be tracked efficiently with 45 minutes of neuropsychological testing. MRI measures of brain atrophy were shown to be less reliable to pick up changes in the same patients.

19 Feb 2014

Experimental drug dinaciclib may improve myeloid leukemia, myeloma therapies

A pre-clinical study led by Virginia Commonwealth University Massey Cancer Center and Department of Internal Medicine researchers suggests that an experimental drug known as dinaciclib could improve the effectiveness of certain multiple myeloma and myeloid leukemia therapies.

19 Feb 2014

Eleven Biotherapeutics announces first pivotal Phase 3 clinical study of EBI-005 for treatment of DED

Eleven Biotherapeutics (NASDAQ: EBIO), a clinical-stage biopharmaceutical company discovering and developing protein therapeutics to treat diseases of the eye, today announced that patient randomization and dosing are underway in the Company's first pivotal Phase 3 clinical study of EBI-005 for the treatment of moderate to severe dry eye disease (DED), the OASIS study (A Multi-Center, Double-Masked, Randomized, Controlled, Efficacy and Safety Study of EBI-005 5 mg/mL Topical Ophthalmic Solution Versus Vehicle Control In Subjects With Moderate to Severe Dry Eye Disease).

19 Feb 2014

DFTD study explains how human selection alters evolution of cancerous cells

Tasmanian Devil Facial Tumour Disease (DFTD) has ravaged the world's largest carnivorous marsupial since it emerged in 1996, resulting in a population decline of over 90%.

19 Feb 2014

Medical Condition News

Deficiency in SNX27 explains learning impairment in Down's syndrome

Medications to lower blood pressure after stroke does not reduce likelihood of death

Antidepressant medication shows potential in treating symptoms of agitation that occur with AD

New information on pathogenesis of feeding and swallowing difficulties in kids with autism

Cystinosis Research Foundation granted $2.15M in 2013 to researchers investigating cure for cystinosis

Indacaterol/glycopyrronium drug combination offers added benefit for adults with COPD

Too much sedentary time linked to major disability after 60

Researchers explore possible link between metabolic defects and seizures

How do people become depressed? An interview with Anna Watters and Professor Lea Williams, University of Sydney

Young adults with high blood pressure often not prescribed medication

Omeros doses first patient in second Phase 2 clinical trial of OMS824

Physicians’ attitudes about obesity may affect patients’ success in losing weight

Researchers develop method for diagnosis and prognosis of cutaneous melanoma

UH Case Medical Center cardiologists perform TAVR procedure under twilight

Researchers examine impact of diet for preventing Alzheimer's dementia

Researchers reveal effectiveness of web-based weight-loss programs

Neuropsychological assessment efficiently tracks disease progression in memory clinic patients

Experimental drug dinaciclib may improve myeloid leukemia, myeloma therapies

Eleven Biotherapeutics announces first pivotal Phase 3 clinical study of EBI-005 for treatment of DED

DFTD study explains how human selection alters evolution of cancerous cells

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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