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ImmunoGen decides to stop IMGN901 Phase II SCLC study

ImmunoGen, Inc., a biotechnology company that develops novel anticancer therapeutics using its antibody-drug conjugate technology, announced today the decision to stop the IMGN901 Phase II SCLC study, following the recommendation of the trial's independent Data Monitoring Committee.

6 Nov 2013

Gambling addiction leads to brain function abnormalities that affect decision-making capacity

University of Granada researchers have analysed similarities and differences in psychological profile and brain function when comparing cocaine addicts and gambling addicts. The study reveals that gambling addicts present brain function abnormalities affecting their decision-making capacity.

6 Nov 2013

Early-life stress suspected to contribute to development of chronic pain in adulthood

Childhood neglect and abuse, whether physical or psychological, confers a lifetime vulnerability to stress, anxiety, and mood problems. Such early-life stress is also suspected to contribute to the development of chronic pain in adulthood.

6 Nov 2013

Interactive multimedia computer program does not improve mental health in depressed patients

Among depressed patients evaluated in a primary care setting, use of an interactive multimedia computer program immediately prior to a primary care visit resulted in the increased receipt of antidepressant prescription recommendation, mental health referral, or both; however, it did not result in improvement in mental health at 12-week follow-up, according to a study in the November 6 issue of JAMA.

6 Nov 2013

Scientists investigate combined action of two different compounds against CML

Currently no treatment option is available for five percent of patients suffering from chronic myelogenous leukemia, since they have developed resistance to conventional medications. Prof. Stephan Grzesiek's group at the Biozentrum of the University of Basel, in collaboration with Dr. Wolfgang Jahnke and colleagues from Novartis, has investigated the combined action of two different compounds against this form of leukemia.

6 Nov 2013

Researchers use machine learning approach to accurately diagnose breast cancer

Software that can recognize patterns in data is commonly used by scientists and economics. Now, researchers in the US have applied similar algorithms to help them more accurately diagnose breast cancer.

6 Nov 2013

Study: Interactions between inflammation and changes in gut microbiota may result in colon tumors

Transferring the gut microbes from a mouse with colon tumors to germ-free mice makes those mice prone to getting tumors as well, according to the results of a study published in mBio-, the online open-access journal of the American Society for Microbiology.

6 Nov 2013

Treadmill training improves functional recovery, neural plasticity after incomplete spinal cord injury

A large body of evidence shows that spinal circuits are significantly affected by training, and that intrinsic circuits that drive locomotor tasks are located in lumbosacral spinal segments in rats with complete spinal cord transection.

6 Nov 2013

Olympic gold medallist opens new Leicester Diabetes Centre

Five-time Olympic gold medallist Sir Steve Redgrave will officially open the new Leicester Diabetes Centre on Thursday 7 November 2013.

6 Nov 2013

Bioniche Life Sciences announces financial results for first quarter of Fiscal 2014

Bioniche Life Sciences Inc., a research-based, technology-driven Canadian biopharmaceutical company, today announced financial results for the first quarter of Fiscal 2014 (ended September 30, 2013).

6 Nov 2013

FDA grants Orphan Drug Designation to Advaxis' ADXS-HPV for HPV-associated head and neck cancer

Advaxis, Inc.,, a leader in developing the next generation of cancer immunotherapies, announced that it has been granted Orphan Drug Designation from the U.S. Food and Drug Administration Office of Orphan Products Development for ADXS-HPV, its lead drug candidate, for the treatment of human papillomavirus-associated head and neck cancer.

6 Nov 2013

Research: Chronic stress changes gene activity in immune cells before reaching bloodstream

New research shows that chronic stress changes gene activity in immune cells before they reach the bloodstream. With these changes, the cells are primed to fight an infection or trauma that doesn't actually exist, leading to an overabundance of the inflammation that is linked to many health problems.

6 Nov 2013

Autoantibodies are detected years before symptom onset in patients with Sjögren syndrome

Autoantibodies are present many years before symptom onset in patients with primary Sjögren syndrome, an autoimmune disease, according to a Research Letter published in the November 6 issue of JAMA.

6 Nov 2013

Sound Pharmaceuticals completes enrollment for SPI-1005 Phase 2 clinical trial

Sound Pharmaceuticals has successfully completed enrollment of its Phase 2 clinical trial with SPI-1005 at the University of Florida. This study enrolled 80 healthy subjects with normal or slight hearing loss and exposed the volunteer to calibrated music using an iPod and insert earphones.

5 Nov 2013

Ventana partners with Incyte to develop companion diagnostic tests for oncology drug programs

Ventana Medical Systems, Inc., a member of the Roche Group, today announced that it has entered into an agreement with Incyte Corporation to collaborate on the development of companion diagnostic tests for Incyte's oncology drug programs, beginning with the Incyte IDO1 inhibitor program.

5 Nov 2013

Cellular Biomedicine Group gets approval to conduct ReJoin Phase IIb trial for Knee Osteoarthritis

Cellular Biomedicine Group, Inc., a biomedicine firm engaged in the development of new treatments for degenerative and cancerous diseases, today announced that it has received approval to conduct a Phase IIb clinical trial for ReJoin, a human adipose-derived mesenchymal precursor cells (haMPC) therapy bio-engineered for Knee Osteoarthritis.

5 Nov 2013

Aeterna Zentaris submits macimorelin acetate NDA to FDA

Aeterna Zentaris Inc. today announced that it has submitted a New Drug Application to the U.S. Food and Drug Administration ("FDA") for its ghrelin agonist, macimorelin acetate (AEZS-130).

5 Nov 2013

Stanford researchers receive $1.37M grant to study on immune systems of pediatric cancer patients

Kathleen Sakamoto, MD, PhD, and Irving Weissman, MD, of the Stanford University School of Medicine and Lucile Packard Children's Hospital, have received a $1.37 million grant from CureSearch for Children's Cancer to research the effects of an antibody that has been shown to be effective against human cancers in animal models.

5 Nov 2013

HSS study shows exercise program helps reduce arthritis pain for Asian seniors

Experts say it's never too late to reap the benefits of exercise, and a program offered in New York City senior centers is improving quality of life for many older adults.

5 Nov 2013

Weight loss surgery: The most effective weapon for obese people in the battle against diabetes

Noted bariatric surgeon Michael Feiz, M.D., F.A.C.S., believes that there's no time like American Diabetes Month to point out that weight loss surgery is the most effective weapon obese people have in the battle against diabetes.

5 Nov 2013

Medical Condition News

ImmunoGen decides to stop IMGN901 Phase II SCLC study

Gambling addiction leads to brain function abnormalities that affect decision-making capacity

Early-life stress suspected to contribute to development of chronic pain in adulthood

Interactive multimedia computer program does not improve mental health in depressed patients

Scientists investigate combined action of two different compounds against CML

Researchers use machine learning approach to accurately diagnose breast cancer

Study: Interactions between inflammation and changes in gut microbiota may result in colon tumors

Treadmill training improves functional recovery, neural plasticity after incomplete spinal cord injury

Olympic gold medallist opens new Leicester Diabetes Centre

Bioniche Life Sciences announces financial results for first quarter of Fiscal 2014

FDA grants Orphan Drug Designation to Advaxis' ADXS-HPV for HPV-associated head and neck cancer

Research: Chronic stress changes gene activity in immune cells before reaching bloodstream

Autoantibodies are detected years before symptom onset in patients with Sjögren syndrome

Sound Pharmaceuticals completes enrollment for SPI-1005 Phase 2 clinical trial

Ventana partners with Incyte to develop companion diagnostic tests for oncology drug programs

Cellular Biomedicine Group gets approval to conduct ReJoin Phase IIb trial for Knee Osteoarthritis

Aeterna Zentaris submits macimorelin acetate NDA to FDA

Stanford researchers receive $1.37M grant to study on immune systems of pediatric cancer patients

HSS study shows exercise program helps reduce arthritis pain for Asian seniors

Weight loss surgery: The most effective weapon for obese people in the battle against diabetes

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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