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Latrepiridine reduces level of at least two neurodegeneration-related proteins in mice

The second of two studies on latrepirdine, recently published in Molecular Psychiatry, demonstrates new potential for the compound in the treatment of Alzheimer's disease, Parkinson's disease, sleep disorders, and other neurodegenerative conditions.

14 Aug 2012

External stimulation impacts postnatal development of brain's white matter

A team at Children's National Medical Center has found that external stimulation has an impact on the postnatal development of a specific region of the brain. Published in Nature Neuroscience, the study used sensory deprivation to look at the growth and collection of NG2-expressing oligodendrocyte progenitor cells (NG2 cells) in the sensory cortex of the brain.

14 Aug 2012

New type of medical imaging could help doctors spot tumors more quickly

Scientists from the University of Southern California in Los Angeles and Washington University in St. Louis have developed a new type of medical imaging that gives doctors a new look at live internal organs.

14 Aug 2012

Mayo Clinic's Individualizing Medicine Conference to be held from Oct. 1-3

Mayo Clinic's Individualizing Medicine Conference, scheduled for Oct. 1-3, will draw experts from around the world to discuss the use of genomics in patient care. Physicians and researchers in this rapidly growing field are building a new type of medicine based on the genomic and molecular interactions that make each patient unique.

14 Aug 2012

National HCGNE announces $1.38M in awards to Claire M. Fagin Fellows, Patricia G. Archbold Scholars

The National Hartford Centers of Gerontological Nursing Excellence (HCGNE) today announced $1.38 million in awards to the latest cohort of Claire M. Fagin Fellows and Patricia G. Archbold Scholars studying gerontological nursing in academic settings across the U.S.

14 Aug 2012

Tai Chi improves health and quality of life for COPD sufferers

A new University of Sydney study has found Tai Chi can be an effective form of exercise therapy for people with chronic obstructive pulmonary disease (COPD), improving exercise capacity and quality of life.

14 Aug 2012

Targeting elevated HLX gene expression may treat acute myeloid leukemia

Scientists at Albert Einstein College of Medicine of Yeshiva University have made a discovery involving mice and humans that could mean that people with acute myeloid leukemia (AML), a rare and usually fatal cancer, are a step closer to new treatment options. Their study results were published online today in Cancer Cell.

14 Aug 2012

Novel method identifies new oncogene that contributes to development of cancer

A team of researchers at Case Western Reserve University School of Medicine, led by Dr. Mark W. Jackson, have developed a novel method to identify genes that, when overexpressed, make normal cells behave like cancer cells.

14 Aug 2012

UD professor part of NIH-funded project to create artificial salivary glands

University of Delaware professor Xinqiao Jia is part of a research team breaking new ground in the creation of artificial salivary glands.

14 Aug 2012

Study: Diabetes drugs increase patients' risk of bladder cancer

A popular class of diabetes drugs increases patients' risk of bladder cancer, according to a new study published online this month in the Journal of the National Cancer Institute.

14 Aug 2012

Gadd45a protein plays a key role in skeletal muscle atrophy

Whether you're old, have been ill, or suffered an injury, you've watched gloomily as your muscles have atrophied. The deterioration of muscle-even slight or gradual-is about as common to the human condition as breathing.

14 Aug 2012

New class of drugs may prove useful in treating cancer and aging-associated disorders

In a study published in the Proceedings of the National Academy of Sciences (PNAS) on Aug. 6, an international team led by Igor Roninson, of the University of South Carolina and the Medical University of South Carolina, reported the development of a new class of drugs that may prove useful in the treatment of cancer and aging-associated disorders.

14 Aug 2012

Pathway describes how alpha hydroxyl acids cause skin exfoliation

A team of investigators from UC Davis and Peking University have discovered a mechanism that may explain how alpha hydroxyl acids (AHAs) -- the key ingredient in cosmetic chemical peels and wrinkle-reducing creams -- work to enhance skin appearance. An understanding of the underlying process may lead to better cosmetic formulations as well as have medical applications.

14 Aug 2012

Eating egg yolks accelerates atherosclerosis in a manner similar to smoking

Newly published research led by Dr. David Spence of Western University, Canada, shows that eating egg yolks accelerates atherosclerosis in a manner similar to smoking cigarettes.

14 Aug 2012

Researchers identify molecular pathway by which Notch regulates cell proliferation in lung cancer

Lung cancer is one of the most aggressive types of cancer and the most common cause of death from this disease worldwide. Despite the progress in the molecular biology of lung cancer achieved in recent years, the mechanisms used by tumor cells to grow and spread throughout the body are not yet completely understood. This lack of information is responsible for the limited range of available therapeutic possibilities and their undesirable side effects.

14 Aug 2012

FDA extends PDUFA target action date for review of Santarus' UCERIS NDA

Santarus, Inc. today announced that the U.S. Food and Drug Administration (FDA) has extended the Prescription Drug User Fee Act (PDUFA) target action date for the review of the New Drug Application (NDA) for UCERIS (budesonide) tablets 9 mg for the induction of remission of mild to moderate active ulcerative colitis from October 16, 2012 to January 16, 2013.

14 Aug 2012

BUSM part of Transthyretin Amyloidosis Cardiac Study

Researchers at Boston University School of Medicine (BUSM) have been part of a multicenter observational study called TRACS (Transthyretin Amyloidosis Cardiac Study) to help determine the health significance of a particular gene mutation which is commonly found in Black Americans.

14 Aug 2012

Springer to publish book series in cooperation with The Breast Cancer Research Foundation

Springer will publish a series of books in cooperation with The Breast Cancer Research Foundation (BCRF) starting in 2013. Four books will be published annually, and will be included in the Springer series Advances in Experimental Medicine and Biology.

14 Aug 2012

Health law critically important to women; Expanding Medicaid could spur state education cuts; Misuse of antipsychotics in dementia patients

If we can set aside the political wrangling and focus on the benefits of the Affordable Care Act, what becomes obvious is its critically important impact on women's health. The fact is while women are the primary coordinators of health care for families and comprise the majority of U.S. health-care workers, they also put their own health-care needs behind those of their children. Cost is too often the reason.

13 Aug 2012

FDA approves Intelliject's Auvi-Q for anaphylaxis

Intelliject, Inc. announced that the U.S. Food and Drug Administration approved Auvi-Q (epinephrine injection, USP) for the emergency treatment of life-threatening allergic reactions in people who are at risk or have a history of anaphylaxis. This is the first-and-only compact auto-injector with audio and visual cues that guide patients and caregivers step-by-step through the injection process.

13 Aug 2012