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Researchers discover amyloid protein buildup in bone marrow of aging mice

A recent study led by a team of researchers at The Johns Hopkins University School of Medicine examining aging mice has provided what is believed to be the first evidence that amyloid beta protein-small, sticky protein fragment found in people with Alzheimer's disease (AD)-particles build up in the bone marrow of the animals, although not in the exact same form as the large, dense plaques found in the brains of people with Alzheimer's disease.

5 Aug 2025

New initiative expands screening for cardiovascular disease marker in community health centers

Elevated lipoprotein(a), also known as Lp(a), is an independent, inherited and causal risk factor for cardiovascular disease, the leading cause of death and disability worldwide.

5 Aug 2025

New policy statement highlights major gaps in U.S stroke rehabilitation and urges better care

Stroke remains a leading cause of long-term disability in the United States, and while treatments have advanced, systems designed to support stroke survivors in recovery continue to fall short of the needs of patients.

5 Aug 2025

Lipid droplet protein perilipin 2 linked to poor prognosis in lung cancer

New research has revealed that perilipin 2 protein modulates aggressive cancer progression in advanced lung adenocarcinoma, the most common type of lung cancer, by regulating lipid droplet accumulation, which plays an important role in lipid metabolism by making cancer cells store more fat, acting as a fuel source.

5 Aug 2025

Most Americans oppose fast food sales in hospitals

Fast food like cheeseburgers, fried chicken, and pizza shouldn't be sold in hospitals, say most Americans in a new Physicians Committee for Responsible Medicine/Morning Consult poll.

5 Aug 2025

Bacteria-based cancer therapy achieves tumor eradication without immune cells

A joint research team led by Professor Eijiro Miyako of the Japan Advanced Institute of Science and Technology (JAIST), in collaboration with Daiichi Sankyo Co., Ltd. and University of Tsukuba, has developed a groundbreaking immune-independent bacterial cancer therapy using a novel microbial consortium called AUN.

5 Aug 2025

AI model advances prediction of microsatellite status in cancer

One in every three people is expected to have cancer in their lifetime, making it a major health concern for mankind.

5 Aug 2025

Breakthrough study reveals potential treatment path for ALS

Amyotrophic lateral sclerosis (ALS), known as Lou Gehrig's disease, is an incurable neurological disorder affecting motor neurons-nerve cells in the brain and spinal cord that control voluntary muscle movement and breathing.

5 Aug 2025

Metabolite patterns reveal potential for COPD population screening

The possibility of having a tool that facilitates population screening for Chronic Obstructive Pulmonary Disease (COPD) is getting closer.

5 Aug 2025

Personalized CPAP treatment could reduce cardiovascular risk in sleep apnea patients

Findings suggest a personalized approach to recommending CPAP machines to patients with obstructive sleep apnea may decrease adverse cardiovascular events.

5 Aug 2025

Early immunotherapy shows promise for treating anti-IgLON5 disease

Researchers ask physicians to consider anti-IgLON5 disease if certain symptoms are present, as the only promising approach is early treatment.

5 Aug 2025

Gfi1 regulates exhausted CD8+ T cells to improve cancer immunotherapy

Killer immune cells destroy cancer cells and cells infected by virus. These CD8+ T cells are activated after detection of viral infection or growth of "non-self" tumor cells.

5 Aug 2025

Fecal transplant may cut infections in long-term care patients

Fecal microbiota transplantation in long-term care patients shows safety and potential to lower infection rates, despite persistent drug-resistant colonization.

5 Aug 2025

Cannabis use disorder triples five-year risk of oral cancer

Research shows cannabis use disorder triples the risk of oral cancer, challenging perceptions of cannabis safety and prompting calls for health screenings.

5 Aug 2025

'Two-in-one' RNA molecule can simultaneously turn off two difficult-to-target cancer-related genes

University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a "two-in-one" molecule that can simultaneously turn off two notoriously difficult-to-target cancer-related genes, KRAS and MYC, as well as directly deliver drugs to tumors that express these genes.

4 Aug 2025

New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025

Leptin could offer alternative to insulin for managing type 1 diabetes complication

More than a decade ago, researchers found that an acute complication of type 1 diabetes, diabetic ketoacidosis (DKA), can be resolved with the hormone leptin, even in the absence of insulin.

4 Aug 2025

Mailing at-home test boosts colorectal cancer screening in adults under 50

In a new study aimed at identifying the best approach to promote colorectal cancer screening in adults ages 45 to 49, UCLA researchers found that simply mailing a stool-based test directly to people's homes was the most effective strategy for increasing screening rates.

4 Aug 2025

New brainwave marker identified for Alzheimer’s detection

Using a custom-built tool to analyze electrical activity from neurons, researchers at Brown University have identified a brain-based biomarker that could be used to predict whether mild cognitive impairment will develop into Alzheimer's disease.

4 Aug 2025

Chemical in everyday products found to worsen alcohol-related liver damage

Have you ever wondered why some people who drink alcohol develop serious liver problems while others don't? A study from University of Louisville researchers published in May in Toxicological Sciences suggests that the answer might be hidden in everyday sources such as drinking water, food packaging or even non-stick cookware.

4 Aug 2025