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Natural product derivative demonstrates promising therapeutic potential for psoriasis

Announcing a new publication for Acta Materia Medica journal. Phosphodiesterase-4 (PDE4), a member of the phosphodiesterase superfamily, has highly important roles in cyclic nucleotide signaling pathways and a variety of skin disorders.

25 Mar 2025

New trial aims to make rectal cancer more responsive to radiation

City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, has opened a phase 1 trial seeking to one day transform rectal cancer from a mostly radiation-resistant disease to one that can be cured using radiation and chemotherapy.

25 Mar 2025

Blood test shows high accuracy in detecting Alzheimer's in Asian populations

A study in Alzheimer's & Dementia, a leading journal in dementia research, has demonstrated the high accuracy of plasma p-tau217 as a blood-based biomarker for detecting abnormal brain beta-amyloid (Aβ) pathology, a hallmark of Alzheimer's disease (AD).

25 Mar 2025

Microplastics exposure linked to increased risk of chronic diseases

Tiny fragments of plastic have become ubiquitous in our environment and our bodies. Higher exposure to these microplastics, which can be inadvertently consumed or inhaled, is associated with a heightened prevalence of chronic noncommunicable diseases, according to new research being presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

25 Mar 2025

Increased mobility linked to lower risk of hospitalization in heart failure patients

Compared with those who spent most of their time in a single room, people with heart failure with preserved ejection fraction (HFpEF) who were able to travel outside of their home without assistance were significantly less likely to be hospitalized or die within a year, according to a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

25 Mar 2025

New evidence suggests HPV could increase risk of coronary artery disease

In addition to causing several types of cancer, human papillomavirus (HPV) appears to bring a significantly increased risk of heart disease and coronary artery disease, according to a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

25 Mar 2025

Mapping the brain network behind generalized epilepsy

Frederic L.W.V.J. Schaper, MD, PhD, director of Epilepsy Network Mapping at the Center for Brain Circuit Therapeutics at Brigham and Women's Hospital and an instructor of neurology at Harvard Medical School, is the senior author of a paper published in Nature Communications, "A generalized epilepsy network derived from brain abnormalities and deep brain stimulation."

25 Mar 2025

High-salt diet induces depression-like symptoms in mice

A new study published in The Journal of Immunology found that a high-salt diet (HSD) induces depression-like symptoms in mice by driving the production of a protein called IL-17A.

25 Mar 2025

Scientists find links between bipolar disorder and rare loss-of-function variants in two genes

Scientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between bipolar disorder and rare loss-of-function variants in two genes.

25 Mar 2025

ADHD may be linked to increased risk of developing dementia later in life

An adult brain affected by attention deficit disorder with or without hyperactivity (ADHD) presents modifications similar to those observed in individuals suffering from dementia.

25 Mar 2025

New study links metabolic defects to Dravet syndrome

New research from the University of Colorado Anschutz Medical Campus is the first to identify defects related to metabolism (how the body processes and uses energy) in lymphoblast cell lines (LCLs) derived from blood samples of children with Dravet syndrome.

25 Mar 2025

High-performing clinics share effective strategies for chronic care follow-up

Regular follow-up visits are critical for managing chronic conditions, yet some primary care clinics achieve higher visit regularity than others.

24 Mar 2025

More chest X-rays in GP practices lead to better lung cancer survival rates

A groundbreaking study has revealed a significant link between the frequency of chest x-ray referrals from GPs and earlier diagnosis and improved survival rates for lung cancer patients.

24 Mar 2025

New brain circuit involved in motion sickness could help improve metabolic health

Motion sickness is a very common condition that affects about 1 in 3 people, but the brain circuits involved are largely unknown. In the current study published in Nature Metabolism, researchers at Baylor College of Medicine, the University of Texas Health Science Center at Houston and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital describe a new brain circuit involved in motion sickness that also contributes to regulating body temperature and metabolic balance.

24 Mar 2025

Besifovir dipivoxil maleate offers comparable efficacy and improved safety for hepatitis B patients

Hepatitis B is a liver infection cause by the hepatitis B virus (HBV), and long-term hepatitis B infections that last longer than six months are considered "chronic".

24 Mar 2025

Study links type 2 diabetes to weakened reward signals in the brain

The high comorbidity of type 2 diabetes (T2D) with psychiatric or neurodegenerative disorders points to a need for understanding what links these diseases.

24 Mar 2025

Family-based approach to lifestyle interventions can reduce weight and cardiovascular risks

The PROgramme of Lifestyle Intervention in Families for Cardiovascular risk reduction (PROLIFIC) Study, conducted in India, aimed to assess whether a family-based approach to lifestyle interventions could improve weight management and obesity-related health outcomes among individuals with a family history of premature coronary heart disease.

24 Mar 2025

Long-term inhaled corticosteroids linked to increased health risks in COPD patients

Inhaled corticosteroids (ICS) are commonly prescribed for chronic obstructive pulmonary disease (COPD), but not recommended as first-line treatment unless patients have asthma/COPD overlap or frequent exacerbations.

24 Mar 2025

Researchers develop TIM-3 decoy to enhance CAR-T therapy effectiveness for B-ALL tumors

B-cell Acute Lymphoblastic Leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common childhood cancer, making up 35% of pediatric cancer cases, but it can affect people of any age.

24 Mar 2025

Smell-based test taken at home could predict cognitive impairment in older adults

When it comes to early detection of cognitive impairment, a new study suggests that the nose knows. Researchers from Mass General Brigham developed olfactory tests-in which participants sniff odor labels that have been placed on a card-to assess people's ability to discriminate, identify and remember odors.

24 Mar 2025

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Medical Condition News

Natural product derivative demonstrates promising therapeutic potential for psoriasis

New trial aims to make rectal cancer more responsive to radiation

Blood test shows high accuracy in detecting Alzheimer's in Asian populations

Microplastics exposure linked to increased risk of chronic diseases

Increased mobility linked to lower risk of hospitalization in heart failure patients

New evidence suggests HPV could increase risk of coronary artery disease

Mapping the brain network behind generalized epilepsy

High-salt diet induces depression-like symptoms in mice

Scientists find links between bipolar disorder and rare loss-of-function variants in two genes

ADHD may be linked to increased risk of developing dementia later in life

New study links metabolic defects to Dravet syndrome

High-performing clinics share effective strategies for chronic care follow-up

More chest X-rays in GP practices lead to better lung cancer survival rates

New brain circuit involved in motion sickness could help improve metabolic health

Besifovir dipivoxil maleate offers comparable efficacy and improved safety for hepatitis B patients

Study links type 2 diabetes to weakened reward signals in the brain

Family-based approach to lifestyle interventions can reduce weight and cardiovascular risks

Long-term inhaled corticosteroids linked to increased health risks in COPD patients

Researchers develop TIM-3 decoy to enhance CAR-T therapy effectiveness for B-ALL tumors

Smell-based test taken at home could predict cognitive impairment in older adults

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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