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Suppression of cdc42 activity could be a promising therapy for nephrotic syndrome

A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University revealed that elevated activity of cdc42 is a critical initiation event leading to proteinuria, and proposed that suppression of cdc42 activity could be a promising therapy for nephrotic syndrome.

6 Aug 2025

Mediterranean diet delivers gut health benefits for expectant mothers

A Mediterranean diet during pregnancy significantly alters the maternal gut microbiome, increasing beneficial bacteria, while a mindfulness-based stress reduction program shows more limited effects. Neither intervention affected the vaginal microbiome, and the clinical significance of these changes requires further study.

6 Aug 2025

Vitamin D supplementation linked to improved cardiometabolic health

A latest systematic review and meta-analysis conducted by scientists from institutions across China and the United States has uncovered promising insights into how vitamin D supplementation can significantly impact cardiometabolic health.

6 Aug 2025

Lifelong learning helps older adults build mental resilience

In a pair of new studies, researchers found that older adults who challenge themselves to learn new things are less likely to experience loneliness or depression, even during times of major upheaval.

6 Aug 2025

Cedars-Sinai study finds new way to combat Alzheimer’s in preclinical models

In a preclinical study, Cedars-Sinai investigators found that boosting angiotensin converting enzyme (ACE) in key immune cells called microglia in the brain helped protect the brains of specially bred laboratory mice against Alzheimer's disease.

6 Aug 2025

Faster and further walking lowers heart disease and stroke risks

Analysis of over 36,000 people with high blood pressure has shown that taking more steps, even below the recommended daily target of 10,000 steps, and walking faster, is associated with a significant reduction in the risk of major problems of the heart and blood vessels.

6 Aug 2025

Scientists map the genes behind diet and dementia risk

Researchers established a high-quality genetic dataset from the MIND diet trial, enabling new studies of gene–diet interactions in cognitive health. This resource allows deeper investigation into why individuals respond differently to dietary interventions targeting dementia risk.

6 Aug 2025

Pregnancy complications may signal early stroke risk

Experiencing complications during pregnancy is linked with a higher risk of stroke before age 50, according to a study published August 6, 2025, in Neurology®, the medical journal of the American Academy of Neurology.

6 Aug 2025

Eating French fries raises type 2 diabetes risk, major study finds

A large, multi-decade cohort study found that frequent French fry consumption raises type 2 diabetes risk, while baked, boiled, or mashed potatoes do not. Swapping any type of potato for whole grains, but not white rice, lowers diabetes risk.

6 Aug 2025

Wearable devices could predict cardiovascular disease risk

Wearable health technology tracks more than just your steps these days.

6 Aug 2025

Innovative VR therapy helps ease anxiety in cardiovascular disease

Living with cardiovascular disease often takes a serious emotional toll - and with stress known to worsen heart health, there's growing interest in low-risk, innovative ways to help patients cope.

6 Aug 2025

Targeted microglia replacement shows promise against fatal neurodegenerative conditions

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

6 Aug 2025

Many patients with high-risk myelodysplastic syndromes do not receive guideline-recommended treatment

Most patients with high-risk myelodysplastic syndromes (MDS) do not receive guideline-recommended treatment with hypomethylating agents (HMAs), according to results published in Blood Neoplasia.

6 Aug 2025

Air purifiers can lower blood pressure in at-risk adults

Using portable high-efficiency particulate air (HEPA) purifiers at home can significantly lower systolic blood pressure (SBP) in adults with elevated baseline readings — even in areas with relatively low overall air pollution levels, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

6 Aug 2025

Immune aging drives the progression of type 2 diabetes

Type 2 diabetes (T2D) is a global metabolic epidemic driven by insulin resistance (IR), chronic inflammation, and β-cell failure.

6 Aug 2025

Alzheimer’s risk factors look different for men and women

Research on Alzheimer's risk factors shows significant sex differences, with implications for diagnosis and treatment in early-onset and late-onset cases.

6 Aug 2025

Nanoparticles could slow rheumatoid arthritis progression and reduce flare severity

As a chronic condition, rheumatoid arthritis (RA) can't be cured, so treatment focuses on managing the disease and controlling its progression. Although current treatments help control RA symptoms in most people, they cannot prevent the onset of RA or painful flare-ups.

6 Aug 2025

TEER shows promising outcomes in elderly patients with atrial functional mitral regurgitation

The mitral valve controls blood flow between the heart's left atrium and ventricle. When structural changes affect the atrium or valve, it may not close fully-causing blood to leak backwards, a condition known as atrial functional mitral regurgitation (AFMR).

6 Aug 2025

Study finds link between past life memories and mental health challenges

Researchers analyzed the profile of adults who claim to have past-life memories, the features of these memories, and their associations with mental health, happiness, and religiosity/spirituality.

6 Aug 2025

New tool offers a more precise way to assess stroke risk in people with atrial fibrillation

Researchers at the University of Vermont have developed a more precise way to assess stroke risk in people with atrial fibrillation (A-Fib), a condition that affects 10.5 million Americans and is a leading cause of stroke.

6 Aug 2025