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Special von Economo neurons may hold key to super-sharp memory in 80+ superagers

Researchers at Northwestern University’s SuperAging Program reveal how some people over 80 retain memory performance like those decades younger, linking it to unique brain structures, reduced pathology, and lower inflammation. Their 25-year study highlights genetic, cellular, and social traits that may protect cognitive function.

10 Aug 2025

Early clinical trial supports MASL as a targeted oral cancer treatment

Rowan University and Sentrimed, a clinical-stage biopharmaceutical company focused on developing safer, orally dosed oncology therapies, today announced results from a National Cancer Institute (NCI) funded clinical trial evaluating MASL in patients with oral squamous cell carcinoma (OSCC).

8 Aug 2025

Lithium deficiency emerges as a hidden driver of Alzheimer’s

What is the earliest spark that ignites the memory-robbing march of Alzheimer’s disease? Why do some people with Alzheimer’s-like changes in the brain never go on to develop dementia? These questions have bedeviled neuroscientists for decades.

8 Aug 2025

Alzheimer’s research reaches a critical tipping point

One-third of people older than 85 in the United States are estimated to live with Alzheimer's disease today, according to the National Institute on Aging.

8 Aug 2025

Understanding the biomarkers and mechanisms associated with anti-NMDAR encephalitis

Encephalitis is a potentially life-threatening condition that involves inflammation of the brain. While some cases of encephalitis are caused by a bacterial or viral infection, other cases of 'autoimmune' encephalitis result when the body's own immune system attacks the brain.

8 Aug 2025

Uncovering the nuclear PIPn-p53 signalosome in cancer cell migration

In this review, the authors present recent findings that uncover a previously unappreciated nuclear signaling hub: the PIPn-p53 signalosome.

8 Aug 2025

New wearable device offers real-time blood pressure monitoring

Seoul National University College of Engineering announced that a research team led by Professor Seung Hwan Ko of the Wearable Soft Electronics Lab, Department of Mechanical Engineering, has developed a wearable electronic device that attaches to the skin like a bandage and enables real-time, continuous monitoring of blood pressure over extended periods.

8 Aug 2025

New blood test offers breakthrough in myeloma diagnosis and monitoring

Researchers at Dana-Farber Cancer Institute have developed a blood test that could transform the diagnosis and monitoring of multiple myeloma (MM) and its precursor conditions.

8 Aug 2025

International commission calls for action against hepatocellular carcinoma

Liver cancer is the sixth most common cancer as well as the third highest cause of cancer-related mortality worldwide.

8 Aug 2025

Exploring the genetic and clinical landscape of clubfoot

A new publication offers an extensive examination of clubfoot, a congenital deformity known as congenital talipes equinovarus (CTEV), affecting about 0.3% of all live births.

8 Aug 2025

Uncovering the secrets of ‘SuperAgers’ and cognitive longevity

For 25 years, scientists at Northwestern Medicine have been studying individuals aged 80 and older - dubbed "SuperAgers" - to better understand what makes them tick.

8 Aug 2025

Study unveils a novel therapeutic solution for diabetic wound healing

Diabetic wounds, particularly foot ulcers, are notorious for their slow and often incomplete healing due to reduced blood flow and endothelial cell dysfunction.

8 Aug 2025

Talking therapy shows lower effectiveness for young adults

Talking therapy offered by the NHS for people with depression or anxiety appears to be less effective for people aged 16-24 than those aged 25-65, according to a new study led by UCL researchers.

8 Aug 2025

Understanding the complex relationship between ultraprocessed foods and health

Ultraprocessed foods or UPFs are a growing concern due to their widespread consumption and impact on potential health risks.

8 Aug 2025

High-dose vitamin D strengthens bones in very low birth weight infants

Research indicates that high-dose vitamin D improves bone health in very low birth weight preterm infants, highlighting its role in early development.

8 Aug 2025

Vital role of physical activity in early type 2 diabetes care

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) shows, among people recently diagnosed with type with type 2 diabetes and no previous cardiovascular disease, a clear association exists between a person's self-reported physical activity and their risk of all-cause mortality and major adverse cardiac events (MACE), that include heart attacks and strokes.

8 Aug 2025

Early treatment withdrawal offers safety and savings for patients with rare kidney disease

Early withdrawal of a treatment for patients with a rare kidney disease is possible without relapse, safer for patients and saves the NHS millions of pounds, new research has revealed.

7 Aug 2025

CRISPR screening uncovers microproteins involved in fat storage

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide.

7 Aug 2025

Genetic testing can guide safer chemotherapy for gastrointestinal cancer patients

For some patients with gastrointestinal (GI) cancers like colorectal and pancreatic cancer, chemotherapy can cause severe, sometimes life-threatening side effects in those who carry certain genetic variants that can impact how their bodies process the drugs used to treat their disease.

7 Aug 2025

Scientists link brain lithium loss to early Alzheimer’s changes

Researchers have discovered that naturally occurring lithium in the brain is depleted early in Alzheimer’s disease, especially in the prefrontal cortex, and that restoring physiological levels with lithium orotate in mice can prevent brain damage and memory loss. The findings suggest lithium deficiency may be a modifiable risk factor for Alzheimer’s.

7 Aug 2025