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Machine learning model outperforms traditional methods in myelofibrosis risk stratification

A machine learning model generated by a team from the European Society for Blood and Marrow Transplantation (EBMT) outperformed standard statistical models in identifying and stratifying transplant risk for patients with myelofibrosis, according to new research published today in Blood, the American Society of Hematology's flagship journal.

27 Mar 2025

Gasdermin D found to play a crucial role in heart arrhythmias

Atrial fibrillation (AF) is a common form of heart arrhythmia, a serious condition in which the heart beats so fast that its upper chambers, the atria, quiver. This irregular heartbeat can increase the risk of severe conditions, including heart failure, dementia and stroke.

27 Mar 2025

Study sheds new light on the mechanisms underlying head and neck cancer metastasis

A recent study published in Engineering has shed new light on the mechanisms underlying the metastasis of head and neck squamous cell carcinoma (HNSCC). The research identified enolase 2 (ENO2), a crucial glycolytic enzyme, as a significant factor associated with lymphatic metastasis in HNSCC.

27 Mar 2025

Simultaneous screening for hypertension and arrhythmia could prevent strokes

A group of 29 international experts says that simultaneous screening for hypertension and heart arrhythmia could prevent thousands of strokes.

27 Mar 2025

AI-powered therapy chatbot shows significant mental health benefits

Dartmouth researchers conducted the first clinical trial of a therapy chatbot powered by generative AI and found that the software resulted in significant improvements in participants' symptoms, according to results published March 27 in the New England Journal of Medicine AI.

27 Mar 2025

AI matches pathologists in diagnosing celiac disease

A machine learning algorithm developed by Cambridge scientists was able to correctly identify in 97 cases out of 100 whether or not an individual had coeliac disease based on their biopsy, new research has shown.

27 Mar 2025

Researchers call for a national strategy to tackle eating disorders

The increasing number of people with eating disorders and a lack of national guidance for support teams has led to researchers calling for a new national strategy that includes specific guidance to support the remote delivery of eating disorder services.

27 Mar 2025

High blood pressure can lead to structural changes in the kidneys

A research team from the Medical University of Vienna has investigated structural changes in kidneys of patients with hypertension and type 2 diabetes.

27 Mar 2025

Transforming genetic deafness treatment with base editing

Congenital hearing loss refers to impaired auditory function that occurs due to genetic causes. GJB2 is the gene responsible for approximately half of all cases of hereditary hearing loss.

27 Mar 2025

Enhancing skin cancer screening with 3D imaging technology

The potential for 3D photography to improve melanoma early detection is a topic of increasing interest in the medical community.

27 Mar 2025

Inhibition of tumor xenograft growth in mice without systemic toxicity

The management of breast cancer involves various therapeutic approaches. However, many current anticancer treatments indiscriminately damage both cancerous and healthy cells. In cancer treatment, Streptomycetes have already been proven as the main resources producing anti-cancer drugs. Streptomyces coelicolor is a representative of the genus Streptomyces.

27 Mar 2025

Novel insights into tumor microenvironment and gastric cancer therapy

A team of Singapore scientists has made a significant discovery in understanding stomach cancer, a disease that remains one of the deadliest cancers worldwide. By using advanced mapping technologies, they created a detailed "atlas" of stomach tumors, revealing hidden patterns in how cancer cells behave, evolve and interact with their environment. These insights could lead to more precise, targeted treatments that improve survival rates and reduce side effects.

27 Mar 2025

Diagnostic colonoscopy follow-up unaffected by COVID-19 surge, despite screening delays

Two recent studies by researchers from Regenstrief Institute and the Indiana University School of Medicine explore the effect of the pandemic on colorectal cancer screening tests and diagnostic colonoscopies in Central Indiana. The findings of temporary disruption to the former and minimal impact on the latter are similar to findings across the U.S., contributing to the compendium of knowledge on preventive health uptake and subsequent treatment in various populations during the pandemic.

27 Mar 2025

Glutamate key to unlocking liver regeneration after acute damage

The liver is a vital organ, crucial to digestion, metabolism and the elimination of toxins. It has a unique ability, regeneration, which allows it to replace liver cells damaged by the very toxins that these cells eliminate.

26 Mar 2025

New protein target could aid in muscle regeneration for degenerative conditions

For millions of people, losing muscle isn't just about weakness; it's about losing independence. Whether caused by Duchenne muscular dystrophy, aging or other degenerative conditions, muscle loss can make everyday activities – like walking, climbing stairs or even standing up – a daily struggle

26 Mar 2025

Wearable technologies may improve exercise adherence in people with Type 2 Diabetes

Wearable mobile health technology could help people with Type 2 Diabetes (T2D) to stick to exercise regimes that help them to keep the condition under control, a new study reveals.

26 Mar 2025

Cabozantinib gains FDA approval for treating advanced neuroendocrine tumors

Cabozantinib, an oral tyrosine kinase inhibitor, has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of patients with previously treated advanced neuroendocrine tumors (NETs).

26 Mar 2025

Study links multimorbidity to increased fall risk and mortality in older adults

A new study by researchers at Peking University and the Chinese PLA General Hospital has found that multimorbidity-living with multiple chronic diseases-is closely associated with worsening fall conditions and mortality among middle-aged and older adults in China.

26 Mar 2025

Over 3.8 million lung cancer deaths prevented in the United States due to smoking decline

New research led by American Cancer Society (ACS) researchers estimates more than 3.8 million lung cancer deaths were averted and a little over 76 million years of life gained in the United States during 1970-2022 due to substantial reductions in smoking prevalence driven by tobacco control.

26 Mar 2025

Study reveals surge in anxiety and distress following the Iranian attack

A new study indicates high levels of emotional distress and anxiety in the days following the Iranian drone and missile attack on Israel on April 13, 2024.

26 Mar 2025