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Epigenetic plasticity in germinal center B cells may help explain lymphoma origins

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more flexible, or plastic, stem-cell-like state in the lymph nodes, according to a new preclinical study from Weill Cornell Medicine investigators.

30 Dec 2025

Inflammation and immune suppression fuel aggressive SCLC behavior and spread

Small cell lung cancer (SCLC) is one of the most aggressive forms of lung cancer, with a five-year survival rate of only five percent. Despite this poor prognosis, SCLC is initially highly responsive to chemotherapy.

30 Dec 2025

Combination therapy offers hope for AML patients facing drug resistance

A research team at Oregon Health & Science University has discovered a promising new drug combination that may help people with acute myeloid leukemia overcome resistance to one of the most common frontline therapies.

30 Dec 2025

Stroke impacts speech sound integration, not speed, study reveals

Following stroke, some people experience a language disorder that hinders their ability to process speech sounds.

30 Dec 2025

Researchers explore why Alzheimer's affects men and women differently

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at the University of Rochester has long been studying this disease and is looking more closely at the differences between male and female brains.

30 Dec 2025

Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer

A new study published today in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in patients with an aggressive subtype of triple-negative breast cancer.

26 Dec 2025

Brain imaging reveals how stimulant drugs improve performance in ADHD

Prescription stimulants, such as Ritalin and Adderall, are widely used to treat attention deficit hyperactivity disorder (ADHD), including in children.

26 Dec 2025

Researchers develop mild mitochondrial uncouplers for obesity treatment

Researchers have developed experimental drugs that encourage the mitochondria in our cells to work a little harder and burn more calories. The findings could open the door to new treatments for obesity and improve metabolic health.

24 Dec 2025

Alcohol consumption plays a major role in India’s mouth cancer burden

Even a low daily intake of alcohol--just 9 g or around one standard drink-is linked to a 50% heightened risk of mouth (buccal mucosa) cancer in India, with the greatest risk associated with locally brewed alcohol, finds a large comparative study, published online in the open access journal BMJ Global Health.

23 Dec 2025

Restoring brain energy balance reverses Alzheimer’s disease in mouse models

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

23 Dec 2025

Artificial intelligence improves risk stratification in oropharyngeal cancer

A team led by investigators at Mass General Brigham and Dana-Farber Cancer Institute has developed and validated an artificial intelligence (AI)–based noninvasive tool that can predict the likelihood that a patient's oropharyngeal cancer-a type of head and neck cancer that develops in the throat-will spread, thereby signaling which patients should receive aggressive treatment.

23 Dec 2025

Older age affects functional recovery after spinal cord injury

A new study published on December 23, 2025, in Neurology, the medical journal of the American Academy of Neurology, looks at how age may affect recovery for people with spinal cord injuries.

23 Dec 2025

Study validates OVCAR3 as a model for high-grade serous ovarian cancer

A new research paper was published in Volume 12 of Oncoscience on October 14, 2025, titled "Bridging clinical insight and laboratory model in high-grade serous ovarian carcinoma (HGSOC) using DNA sequencing-based profiling of TP53."

23 Dec 2025

CT-based quantification of tumor fibrosis guides chemotherapy in pancreatic cancer

On October 3, 2025, a multicenter team from Shenzhen University, Xiangya Hospital of Central South University, Zhujiang Hospital of Southern Medical University, Wuxi People's Hospital Affiliated to Nanjing Medical University, among others jointly reported a novel noninvasive method for quantifying tumor fibrosis based on preoperative enhanced CT.

23 Dec 2025

High-fat cheese and cream consumption links to lower dementia risk over 25 years

Higher intake of high-fat cheese and cream was associated with a lower risk of all-cause dementia over 25 years in a large Swedish cohort, while low-fat dairy showed no association. Associations were strongest for vascular dementia and among APOE ε4 non-carriers, with findings remaining observational.

23 Dec 2025

Study demonstrates significant changes in gut bacteria at the onset of IBD

Patients experience significant changes in gut bacteria at the onset of inflammatory bowel disease (IBD), a new international study has found - offering new hope for earlier diagnosis and future treatments.

23 Dec 2025

Polysaccharide functionalized carbon dot nanovaccine boosts antitumor T cell responses

Recent advancements in cancer vaccine development have demonstrated their potential for precise tumor targeting through antigen-specific immune activation.

23 Dec 2025

Prebiotic microcapsules deliver pterostilbene to the colon to alleviate ulcerative colitis

A team led by clinicians and engineers has wrapped the plant-derived polyphenol pterostilbene (PSB) into prebiotic alginate/resistant-starch microcapsules coated with chitosan and shown that oral administration dampens dextran-sulfate-sodium (DSS) colitis in mice.

23 Dec 2025

Researchers explore a promising approach to enhance the immune system's ability to fight cancer

Researchers at the University of Sharjah are exploring a promising approach that could enhance the immune system's ability to fight cancer, potentially paving the way for new treatments.

23 Dec 2025

Medical bills can be vexing and perplexing. Here’s this year’s best advice for patients.

A Texas boy's second dose of the MMRV vaccine cost over $1,400. A Pennsylvania woman's long-acting birth control cost more than $14,000.

23 Dec 2025

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Medical Condition News

Epigenetic plasticity in germinal center B cells may help explain lymphoma origins

Inflammation and immune suppression fuel aggressive SCLC behavior and spread

Combination therapy offers hope for AML patients facing drug resistance

Stroke impacts speech sound integration, not speed, study reveals

Researchers explore why Alzheimer's affects men and women differently

Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer

Brain imaging reveals how stimulant drugs improve performance in ADHD

Researchers develop mild mitochondrial uncouplers for obesity treatment

Alcohol consumption plays a major role in India’s mouth cancer burden

Restoring brain energy balance reverses Alzheimer’s disease in mouse models

Artificial intelligence improves risk stratification in oropharyngeal cancer

Older age affects functional recovery after spinal cord injury

Study validates OVCAR3 as a model for high-grade serous ovarian cancer

CT-based quantification of tumor fibrosis guides chemotherapy in pancreatic cancer

High-fat cheese and cream consumption links to lower dementia risk over 25 years

Study demonstrates significant changes in gut bacteria at the onset of IBD

Polysaccharide functionalized carbon dot nanovaccine boosts antitumor T cell responses

Prebiotic microcapsules deliver pterostilbene to the colon to alleviate ulcerative colitis

Researchers explore a promising approach to enhance the immune system's ability to fight cancer

Medical bills can be vexing and perplexing. Here’s this year’s best advice for patients.

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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