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Constellation Pharmaceuticals awarded grant to facilitate study of epigenetic control of inflammation

Constellation Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company in the field of epigenetics, today announced that it has been awarded a research grant in collaboration with the University of Pittsburgh School of Medicine from the Cystic Fibrosis Foundation to explore the potential use of BET bromodomain inhibitors for the control of inflammation in cystic fibrosis.

10 Oct 2013

Alkermes' ALKS 5461 drug gets FDA Fast Track status for major depressive disorder

Alkermes plc today announced that the U.S. Food and Drug Administration has granted Fast Track status for ALKS 5461 for the adjunctive treatment of major depressive disorder in patients with an inadequate response to standard therapies.

10 Oct 2013

FDA clears Sotera Wireless' patented continuous non-invasive blood pressure technology

Sotera Wireless, Inc. today announced the U.S. Food and Drug Administration has cleared the Company's patented continuous non-invasive blood pressure technology, a new feature of the ViSi Mobile wireless patient monitoring system. For the first time clinicians can continuously monitor all patient vital signs, including beat-to-beat blood pressure, without the use of a catheter or blood pressure cuff.

10 Oct 2013

Drugs often fail to bring acromegaly under control in routine clinical practice

Over a quarter of UK patients treated for growth hormone-producing tumours do not achieve 'safe' growth hormone levels, according to a 30 year UK multi-centre study of clinical management of the rare disease acromegaly. The findings by the Society for Endocrinology UK Acromegaly Register, published in the November issue of Clinical Endocrinology, show that drugs to control acromegaly often fail to bring the disease completely under control in routine clinical practice.

10 Oct 2013

Combining gene therapy with stem cells leads to faster healing of burns

Johns Hopkins researchers, working with elderly mice, have determined that combining gene therapy with an extra boost of the same stem cells the body already uses to repair itself leads to faster healing of burns and greater blood flow to the site of the wound.

10 Oct 2013

Running a marathon can damage heart muscle for unfit runners

Investigators who studied a group of recreational marathon runners have established that strenuous exercise such as running a marathon can damage the heart muscle. Although they found the effect is temporary and reversible, they warn that these effects are more widespread in less fit distance runners and that recreational distance runners should prepare properly before marathons.

10 Oct 2013

Charles J. Sherr to receive Prize for Scientific Excellence in Medicine

Charles J. Sherr, M.D., Ph.D., chair of the St. Jude Children's Research Hospital Department of Tumor Cell Biology and a Howard Hughes Medical Institute Investigator, has been selected to receive the 2013 Prize for Scientific Excellence in Medicine by the American-Italian Cancer Foundation.

10 Oct 2013

Transcendental Meditation technique has large effect on reducing trait anxiety, shows analysis

A new meta-analysis published today in the Journal of Alternative and Complementary Medicine (2013;19(10):1-12)1 found the Transcendental Meditation- technique (TM) has a large effect on reducing trait anxiety for people with high anxiety.

10 Oct 2013

Intravenous feeding can cause liver damage, say researchers

Researchers know that feeding some patients intravenously can save their lives - but also can cause liver damage. Now scientists at the University of Colorado and Children's Hospital Colorado have figured out the likely culprit, one of the ingredients in intravenous food, behind the liver problems.

10 Oct 2013

Auckland physician performs first patient implant of Boston Scientific Innova DES System

Launching a key clinical trial expected to serve as the foundation for global regulatory approvals, a physician in Auckland, New Zealand has performed the first patient implant of the Boston Scientific Corporation Innova Drug-Eluting Stent System.

10 Oct 2013

Beta-blocker therapy controls heart rate, improves cardiovascular performance in septic shock patients

Andrea Morelli, M.D., of the University of Rome, Italy, and colleagues conducted a study to investigate the effect of the short-acting beta-blocker esmolol on the heart rate of patients with severe septic shock and high risk of death.

10 Oct 2013

Phase 3 study of idelalisibin reports positive results in CLL patients

Following a recommendation by an independent Data Monitoring Committee (DMC), Gilead Sciences, Inc. (Nasdaq:GILD) today announced that its Phase 3 study (Study 116) evaluating idelalisib in previously-treated chronic lymphocytic leukemia (CLL) patients who are not fit for chemotherapy will be stopped early.

10 Oct 2013

Lundbeck, Otsuka to continue development of Lu AE58054 compound for Alzheimer's disease

H. Lundbeck A/S and Otsuka Pharmaceutical Co., Ltd. announced today the continuation of the development program of Lu AE58054 for the treatment of Alzheimer's disease, initiating the first out of four phase III clinical trials with the compound.

10 Oct 2013

Pfizer reports positive results from two tofacitinib Phase 3 trials for chronic plaque psoriasis

Pfizer Inc. announced today top-line results from two Phase 3 clinical trials of tofacitinib, a novel, oral Janus kinase inhibitor that is being investigated for the treatment of adults with moderate-to-severe chronic plaque psoriasis: OPT Compare (A3921080) and OPT Retreatment (A3921111).

10 Oct 2013

Gene mutation offers clues to development of diverse neurological disorders

A research team, headed by Theodore Friedmann, MD, professor of pediatrics at the University of California, San Diego School of Medicine, says a gene mutation that causes a rare but devastating neurological disorder known as Lesch-Nyhan syndrome appears to offer clues to the developmental and neuronal defects found in other, diverse neurological disorders like Alzheimer's, Parkinson's and Huntington's diseases.

10 Oct 2013

Adempas drug gets FDA approval for treatment of pulmonary hypertension

The U.S. Food and Drug Administration today approved Adempas (riociguat) to treat adults with two forms of pulmonary hypertension. Pulmonary hypertension is caused by abnormally high blood pressure in the arteries of the lungs.

10 Oct 2013

Halloween parties can heighten danger for kids with food allergies

The scary reality is that food allergies are becoming more and more common in the United States. In the past 10 years there has been an 18 percent increase in children with food allergies.

10 Oct 2013

Team Ritter to raise funds for John Ritter Foundation for Aortic Health at ING NYC Marathon

Friends and family members of people with thoracic aortic disease and fans of the late legendary comedic actor John Ritter will come together as Team Ritter to raise funds for the John Ritter Foundation for Aortic Health at the ING New York City Marathon on Nov. 3, 2013.

10 Oct 2013

Mayo Clinic study: Baby boomers to witness surge in cataract surgeries

As baby boomers enter their retirement years, health care costs for complex and debilitating conditions such as Alzheimer's disease are expected to soar. Not drawing as much attention is the likelihood of similarly rising expenses for common age-related medical procedures. A Mayo Clinic study looked at one of those -- cataract surgery-- and found that more people are getting the vision-improving procedure, seeking it at younger ages and having both eyes repaired within a few months, rather than only treating one eye.

10 Oct 2013

Kindergarten-age children have poorer health if mother has chaotic work life

Kindergarten-age children have poorer health if their home life is marked by disorder, noise and a lack of routine and they have a mother who has a chaotic work life, new research suggests.

10 Oct 2013

Medical Condition News

Constellation Pharmaceuticals awarded grant to facilitate study of epigenetic control of inflammation

Alkermes' ALKS 5461 drug gets FDA Fast Track status for major depressive disorder

FDA clears Sotera Wireless' patented continuous non-invasive blood pressure technology

Drugs often fail to bring acromegaly under control in routine clinical practice

Combining gene therapy with stem cells leads to faster healing of burns

Running a marathon can damage heart muscle for unfit runners

Charles J. Sherr to receive Prize for Scientific Excellence in Medicine

Transcendental Meditation technique has large effect on reducing trait anxiety, shows analysis

Intravenous feeding can cause liver damage, say researchers

Auckland physician performs first patient implant of Boston Scientific Innova DES System

Beta-blocker therapy controls heart rate, improves cardiovascular performance in septic shock patients

Phase 3 study of idelalisibin reports positive results in CLL patients

Lundbeck, Otsuka to continue development of Lu AE58054 compound for Alzheimer's disease

Pfizer reports positive results from two tofacitinib Phase 3 trials for chronic plaque psoriasis

Gene mutation offers clues to development of diverse neurological disorders

Adempas drug gets FDA approval for treatment of pulmonary hypertension

Halloween parties can heighten danger for kids with food allergies

Team Ritter to raise funds for John Ritter Foundation for Aortic Health at ING NYC Marathon

Mayo Clinic study: Baby boomers to witness surge in cataract surgeries

Kindergarten-age children have poorer health if mother has chaotic work life

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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