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Researchers reveal mechanisms that connect Mfn2 protein to endoplasmic reticulum stress

Each cell in an organism has a sensor that measures the health of its "internal" environment. This "alarm" is found in the endoplasmic reticulum, which is able to sense cellular stress and trigger either rescue responses or the death of the cell.

18 Sep 2013

Study proves advantages of immediate surgery for patients with acute cholecystitis

Should surgery be performed immediately, or is it better to first administer antibiotics and then perform surgery? A study led by Heidelberg University Hospital Department of Surgery has demonstrated that patients suffering from acute cholecystitis should be operated on immediately. There are no advantages to delaying surgery until antibiotic therapy has been administered for several weeks. After undergoing surgery performed within 24 hours of diagnosis, the patients have fewer complications, are back on their feet earlier, and can leave the hospital more quickly.

18 Sep 2013

Winners of Renal Support Network's Annual Essay Contest announced

Now in its 11th year of providing a voice for people who have kidney disease and are passionate about writing, Renal Support Network announces the winners of its Annual Essay Contest.

18 Sep 2013

University of Chicago researchers awarded NIH grant to develop novel multiple sclerosis treatment

Researchers from the University of Chicago have been awarded a five-year, $1.5 million grant from the National Institutes of Health to develop stimulated dendritic cell-derived exosomes that show remarkable promise as a treatment for multiple sclerosis and other neurological diseases involving loss of myelin, the insulation around nerve fibers.

18 Sep 2013

Cognitive barriers, sensory problems put patients at risk of receiving sub-optimal treatment

Patients' inability to communicate because of sensory or cognitive impairment can be a significant barrier to pain management, according to researchers writing in the journal Nursing Older People.

18 Sep 2013

Comprehensive approach to the evaluation of groin pain

She wasn't born this way, but even Lady Gaga experienced groin pain-typically a symptom of hip disease such as arthritis of the hip-or, in her case, a hip labral tear. Groin pain is a common health complaint. According to a literature review appearing in the September 2013 issue of the Journal of the American Academy of Orthopaedic Surgeons, one in four people develop hip arthritis-damage to the surfaces in the hip joint-before the age of 85 that contributes to groin pain.

18 Sep 2013

Scientists isolate, grow stem cells from the pancreases of mice

Scientists have succeeded in growing stem cells that have the ability to develop into two different types of cells that make up a healthy pancreas. The research team led by Dr. Hans Clevers of the Hubrecht Institute, The Netherlands, have isolated and grown stem cells from the pancreases of mice using a 3-D culture system previously developed by the scientists.

18 Sep 2013

SignaBlok's novel peptide inhibitor of TREM-1 suppresses cancer progression

SignaBlok, Inc., a Massachusetts-based biopharmaceutical company, today announced the successful in vivo proof of concept data that demonstrate that the company's novel mechanism-based, first-in-class peptide inhibitor of TREM-1 effectively suppresses cancer progression in mouse models of lung cancer and dramatically improves survival in septic mice.

18 Sep 2013

Handheld device for diagnosing early signs of osteoporosis

A handheld device for diagnosing the early signs of osteoporosis could be available for clinical use within five years.

18 Sep 2013

Intra-articular hyaluronic acid injections safe, effective for patients with knee osteoarthritis

A new meta-analysis of 29 randomized studies involving more than 4,500 patients with knee osteoarthritis found that intra-articular hyaluronic acid injections provided significant improvement in pain and function compared to saline injections.

18 Sep 2013

NHCS researchers discover potential cure for long QT syndrome 2

The National Heart Centre Singapore research team has successfully and completely reversed the effects of the hERG (human ether-a-go-go-related gene) mutation in long QT syndrome 2 in patient-specific heart cells, scoring a world's first.

18 Sep 2013

Obese men who binge are more likely to have elevated cholesterol, high blood pressure

Binge eating is a problem affecting both men and women, however obese men who binge are more likely than their female counterparts to have elevated cholesterol and high blood pressure, finds a new study in General Hospital Psychiatry.

18 Sep 2013

Emotional stress, cognitive impairment linked to early hospital readmission of heart patients

Heart patients' mental state and thinking abilities may help predict whether costly and potentially dangerous early hospital readmission will follow their release after treatment, according to the results of a significant new study by Henry Ford Hospital researchers.

18 Sep 2013

RedHill Biopharma to initiate phase III trial of RHB 104 in Crohn's disease patients

UCF College of Medicine professor Dr. Saleh Naser soon will participate in a clinical trial to test whether a new antibiotic therapy acquired by RedHill Biopharma can be used to treat Crohn's disease patients.

18 Sep 2013

New prototype technique improves diagnosis of cancer tissue during operation

Tissue-conserving cancer surgery is a highly skilled procedure which involves time-consuming tissue preparation to detect the margins of cancerous tissue. The goal is to remove as much of the tumour as possible while sparing healthy tissue.

18 Sep 2013

Researchers develop synthetic peptide that could be a new class of drugs for heart disease

Researchers at the University of Alberta have developed a synthetic peptide that could be the first in a new class of drugs to treat heart disease, high blood pressure and diabetes.

18 Sep 2013

VBP15 drug shows early promise for treatment of Duchenne muscular dystrophy

A preclinical study led by researchers at Children's National Medical Center has found that a new oral drug shows early promise for the treatment of Duchenne muscular dystrophy.

18 Sep 2013

Abnormalities in brain axons predispose people to chronic back pain after injury

Abnormalities in the structure of the brain predispose people to develop chronic pain after a lower back injury, according to new Northwestern Medicine- research. The findings could lead to changes in the way physicians treat patients' pain.

18 Sep 2013

FDA grants Breakthrough Therapy designation to Boehringer Ingelheim's volasertib

Boehringer Ingelheim Pharmaceuticals, Inc. today announced the FDA has granted Breakthrough Therapy designation to volasertib, an investigational inhibitor of polo-like kinase, being evaluated for the treatment of patients aged 65 or older with previously untreated acute myeloid leukemia, ineligible for intensive remission induction therapy.

17 Sep 2013

UCSF neuroscientist wins Barancik Prize for multiple sclerosis research

Neuroscientist Jonah Chan, PhD, at the University of California, San Francisco, is the first recipient of a new international prize launched to recognize innovation and progress in multiple sclerosis research.

17 Sep 2013

Medical Condition News

Researchers reveal mechanisms that connect Mfn2 protein to endoplasmic reticulum stress

Study proves advantages of immediate surgery for patients with acute cholecystitis

Winners of Renal Support Network's Annual Essay Contest announced

University of Chicago researchers awarded NIH grant to develop novel multiple sclerosis treatment

Cognitive barriers, sensory problems put patients at risk of receiving sub-optimal treatment

Comprehensive approach to the evaluation of groin pain

Scientists isolate, grow stem cells from the pancreases of mice

SignaBlok's novel peptide inhibitor of TREM-1 suppresses cancer progression

Handheld device for diagnosing early signs of osteoporosis

Intra-articular hyaluronic acid injections safe, effective for patients with knee osteoarthritis

NHCS researchers discover potential cure for long QT syndrome 2

Obese men who binge are more likely to have elevated cholesterol, high blood pressure

Emotional stress, cognitive impairment linked to early hospital readmission of heart patients

RedHill Biopharma to initiate phase III trial of RHB 104 in Crohn's disease patients

New prototype technique improves diagnosis of cancer tissue during operation

Researchers develop synthetic peptide that could be a new class of drugs for heart disease

VBP15 drug shows early promise for treatment of Duchenne muscular dystrophy

Abnormalities in brain axons predispose people to chronic back pain after injury

FDA grants Breakthrough Therapy designation to Boehringer Ingelheim's volasertib

UCSF neuroscientist wins Barancik Prize for multiple sclerosis research

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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