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NIEHS grant renewal opens next chapter in 18-year research effort into brain injury biomarker

The National Institute of Environmental Health Sciences (NIEHS) has awarded a five-year, $1.5 million grant extension to Columbia University's Mailman School of Public Health to fund research into the function of a biomarker for brain injury called Translocator Protein 18 kDa, better known as TSPO, in order to better understand its function in brain injury and inflammation and discover targets for therapy.

17 Sep 2013

TSRI scientists find new way to boost effectiveness of anticancer drugs

Scientists at The Scripps Research Institute (TSRI) have found a way to make dramatic improvements to the cancer cell-killing power of vinblastine, one of the most successful chemotherapy drugs of the past few decades.

17 Sep 2013

Varenicline drug helps people with depression quit smoking, say researchers

About half of smokers seeking treatment for smoking cessation have a history of depression. Compared with smokers who are not depressed, those who suffer from a major depressive disorder have greater difficulty quitting.

17 Sep 2013

Flecainide, encainide drugs increase risk of sudden cardiac death

Scientists have discovered that a drug which increases the risk of sudden cardiac death interacts with mistranslated protein-coding genes present in heart muscle.

17 Sep 2013

Hospitalizations for endocarditis have declined in recent years

Hospitalizations for endocarditis, a deadly heart infection that disproportionately affects older heart patients, have declined in recent years despite recommendations for limited use of antibiotics to prevent the illness. These findings were recently published by Yale School of Medicine researchers in the Journal of the American College of Cardiology.

17 Sep 2013

Recanalization of extracranial internal carotid artery occlusion: A retrospective study

Carotid endarterectomy can benefit the majority of patients with severe carotid artery stenosis. However, the therapeutic effects of this technique in patients with symptomatic internal carotid artery occlusion remain controversial.

17 Sep 2013

Study reports identification of IDH1 protein as novel biomarker for diagnosis of NSCLC

A protein called isocitrate dehydrogenase is present at high levels in lung cancers and can be detected in the blood, making it a noninvasive diagnostic marker for lung cancers, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

17 Sep 2013

Understanding essential role of gut microbes in immune system

A new understanding of the essential role of gut microbes in the immune system may hold the key to dealing with some of the more significant health problems facing people in the world today, Oregon State University researchers say in a new analysis.

17 Sep 2013

Patients with pre-existing dementia may experience delirium when hospitalized

More than half of all patients with pre-existing dementia will experience delirium while hospitalized. Failing to detect and treat their delirium early leads to a faster decline of both their physical and mental health, according to health researchers.

17 Sep 2013

microRNA-486 found to be potent tumor-suppressor molecule in lung cancer

New research shows that microRNA-486 is a potent tumor-suppressor molecule in lung cancer, and that the it helps regulate the proliferation and migration of lung-cancer cells, and the induction of programmed cell death, or apoptosis, in those cells.

17 Sep 2013

Researchers find mucus-regulating protein receptors out of control in uterine, pancreatic cancers

A "vicious cycle" produces mucus that protects uterine and pancreatic cancer cells and promotes their proliferation, according to researchers at Rice University. The researchers offer hope for a therapeutic solution.

17 Sep 2013

High exposure to swine manure in crop fields linked with increased risk of MRSA, soft-tissue infection

High exposure to swine manure spread in crop fields and proximity to high-density swine livestock operations appear to be associated with increased risk of methicillin-resistant Staphylococcus aureus (MRSA) and skin and soft-tissue infection in humans, according to a study published by JAMA Internal Medicine, a JAMA Network publication.

17 Sep 2013

Repeated exposure to low level blasts causes harmful effects in brain

Repeated exposure to low level blasts (LLB) can cause symptoms similar to sports concussion. Soldiers or law enforcement officers called "breachers" receive training in using low level blasts for forced entry.

17 Sep 2013

Study shows that changes in diet, lifestyle choices may result in longer telomeres

A small pilot study shows for the first time that changes in diet, exercise, stress management and social support may result in longer telomeres, the parts of chromosomes that affect aging.

17 Sep 2013

Researchers identify potentially treatable subtype of pancreatic cancer

Australian researchers have identified a potentially treatable subtype of pancreatic cancer, which accounts for about 2% of new cases. This subtype expresses high levels of the HER2 gene. HER2-amplified breast and gastric cancers are currently treated with Herceptin.

17 Sep 2013

Patients who receive automated telephone calls are more likely to have controlled hypertension

Patients who received automated telephone calls inviting them to get their blood pressure checked at a walk-in clinic were more likely to have controlled hypertension than patients who did not receive calls, according to a Kaiser Permanente study published today in the Journal of Clinical Hypertension.

17 Sep 2013

NJIT student team to develop innovative interactive toys for autistic children

NJIT Distinguished Professor Atam P. Dhawan, PhD, recently joined the autism community at the NJ State House to be recognized for improving public and private autism services.

17 Sep 2013

Researchers identify new link between meal times and daily changes in immune system

A new link between meal times and daily changes in the immune system has been identified by UC San Francisco researchers, and has led them to question assumptions about the roles of specific immune cells in infection and allergy.

17 Sep 2013

Overexpression of cytoglobin gene inhibits hypoxic injury to neuroblastoma cells

Cytoglobin is a temporary oxygen reservoir, which might provide a minimal, but continuous supply of intracellular oxygen during ischemic and anoxic conditions.

17 Sep 2013

Vanderbilt examines ability of drug abatacept to prevent type 1 diabetes

Vanderbilt's Eskind Diabetes Clinic has been selected to examine the ability of the drug abatacept to prevent type 1 diabetes (T1D). As part of the TrialNet consortium, Vanderbilt will be one of 14 North American sites observing the effects of the drug in people at high risk to develop T1D.

17 Sep 2013

Medical Condition News

NIEHS grant renewal opens next chapter in 18-year research effort into brain injury biomarker

TSRI scientists find new way to boost effectiveness of anticancer drugs

Varenicline drug helps people with depression quit smoking, say researchers

Flecainide, encainide drugs increase risk of sudden cardiac death

Hospitalizations for endocarditis have declined in recent years

Recanalization of extracranial internal carotid artery occlusion: A retrospective study

Study reports identification of IDH1 protein as novel biomarker for diagnosis of NSCLC

Understanding essential role of gut microbes in immune system

Patients with pre-existing dementia may experience delirium when hospitalized

microRNA-486 found to be potent tumor-suppressor molecule in lung cancer

Researchers find mucus-regulating protein receptors out of control in uterine, pancreatic cancers

High exposure to swine manure in crop fields linked with increased risk of MRSA, soft-tissue infection

Repeated exposure to low level blasts causes harmful effects in brain

Study shows that changes in diet, lifestyle choices may result in longer telomeres

Researchers identify potentially treatable subtype of pancreatic cancer

Patients who receive automated telephone calls are more likely to have controlled hypertension

NJIT student team to develop innovative interactive toys for autistic children

Researchers identify new link between meal times and daily changes in immune system

Overexpression of cytoglobin gene inhibits hypoxic injury to neuroblastoma cells

Vanderbilt examines ability of drug abatacept to prevent type 1 diabetes

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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