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Icahn School of Medicine at Mount Sinai joins NIH Stroke Trials Network

The Icahn School of Medicine at Mount Sinai joins a top-flight network of 25 regional stroke centers announced by the National Institute of Health that will focus on prevention, treatment, and recovery from stroke. As part of the NIH Stroke Trials Network (NIHStrokeNet), the medical school will receive a 5-year, $1.3 million grant to build a collaborative research infrastructure for a regional coordinating stroke center.

20 Dec 2013

New MDA Endurance Program aims to find treatments and cures for muscle disease

The Muscular Dystrophy Association today announced the formation and launch of MDA Team Momentum, a new nationwide endurance program designed to help support MDA's mission to find treatments and cures for muscle disease.

20 Dec 2013

Oramed reports positive results from ORMD-0801 pharmacokinetic study in type 1 diabetes patients

Oramed Pharmaceuticals Inc., a clinical-stage pharmaceutical company focused on the development of oral drug delivery systems, announced today successful results in a clinical trial testing the pharmacokinetic dose response of its oral insulin capsule (ORMD-0801) in type 1 diabetes patients.

20 Dec 2013

Auxilium seeks FDA approval for XIAFLEX sBLA to treat multiple Dupuytren's contracture cords concurrently

Auxilium Pharmaceuticals, Inc., a fully integrated specialty biopharmaceutical company, today announced the submission of a supplemental Biologics License Application to the U.S. Food and Drug Administration requesting approval of XIAFLEX (collagenase clostridium histolyticum, or CCH) for the treatment of multiple Dupuytren's contracture cords concurrently.

20 Dec 2013

Study reveals that K-Ras gene mutations behave in ways that subvert normal mechanisms of cell death

Cells with a mutation in the gene called K-Ras—found in close to 30 percent of all cancers, but mostly those with worst prognosis, such as pancreatic cancer, colon cancer, and lung cancer—behave in ways that subvert the normal mechanisms of cell death, according to a cell-culture study by researchers from Huntsman Cancer Institute (HCI) at the University of Utah.

20 Dec 2013

Doctors should consider underlying inflammatory conditions when selecting anti-epilepsy drugs, say researchers

Physicians at the Ruhr-Universität Bochum (RUB) have been investigating if established anti-epilepsy drugs have anti-inflammatory or pro-inflammatory properties - an effect for which these pharmaceutical agents are not usually tested.

20 Dec 2013

ESC presents results of pilot registry on management and treatment of AF in Europe

Results for a pilot registry on the management and treatment of atrial fibrillation in Europe were presented yesterday by the European Society of Cardiology. AF is the commonest cardiac rhythm disorder and each of us have a one-in-four lifetime risk of developing it. Statistics show that oral anticoagulant use has increased, but new oral anticoagulant use is still low. Authors also concluded that compliance with treatment guidelines for patients with the lowest and higher stroke risk scores remains suboptimal.

20 Dec 2013

Coupling meditation-like practices with drug and behavior therapies more helpful in tackling addiction

Using a computational model of addiction, a literature review and an in silico experiment, theoretical computer scientist Yariv Levy and colleagues suggest in a new paper this week that rehabilitation strategies coupling meditation-like practices with drug and behavior therapies are more helpful than drug-plus-talk therapy alone when helping people overcome addiction.

20 Dec 2013

New antibody could boost strength, muscle mass in patients with cancer and other diseases

A new antibody could dramatically boost strength and muscle mass in patients with cancer, chronic obstructive pulmonary disease, sporadic inclusion body myositis, and in elderly patients with sarcopenia according to research published ahead of print in the journal Molecular and Cellular Biology.

20 Dec 2013

Experimental drug inhibits BTK molecule in patients with chronic lymphocytic leukemia

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) helps confirm that a molecule targeted by the experimental drug ibrutinib is critical for the development of chronic lymphocytic leukemia, the most common form of adult leukemia.

20 Dec 2013

Joint initiative aims to eradicate health disparities among communities of color in the U.S.

The world's first and largest group medical practice and one of the nation's premier volunteer service organizations of professional African American women are joining forces to eradicate health disparities among communities of color in the United States. Mayo Clinic and The Links, Incorporated have established a formal collaboration that aims to develop a more diverse health care workforce.

20 Dec 2013

IQWiG reassesses vemurafenib for treatment of advanced melanoma

Pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) reassessed vemurafenib (trade name: Zelboraf), a drug for the treatment of adults with a certain type of advanced melanoma.

20 Dec 2013

Amgen reports that Phase 3 DESCARTES study for high cholesterol meets primary endpoint

Amgen today announced that the Phase 3 DESCARTES (Durable Effect of PCSK9 Antibody CompARed wiTh PlacEbo Study) study evaluating the long-term 52-week safety and efficacy of evolocumab for the treatment of high cholesterol met its primary endpoint of percent reduction from baseline in low-density lipoprotein cholesterol (LDL-C) at week 52.

20 Dec 2013

Parkinson's disease patients may find difficulties in recognizing emotions

Patients affected by Parkinson's disease may experience, in addition to the more obvious motor symptoms (such as tremors and stiffness), difficulties recognizing emotions in the facial expressions and speech prosody (intonation) of other people. A number of investigations have shown that even deep brain stimulation, a treatment that has become widely used in recent years, may cause similar disorders.

20 Dec 2013

Sugar-based gelators may provide alternatives to trans fats linked to obesity, heart disease, diabetes

Researchers at The City College of New York have reported the successful transformation of vegetable oils to a semisolid form using low-calorie sugars as a structuring agent.

20 Dec 2013

Study supports mounting evidence that inflammation may be the cause of chronic rhinosinusitis

Saint Louis University researchers have analyzed the microbiomes of people with chronic rhinosinusitis and healthy volunteers and found evidence that some chronic sinus issues may be the result of inflammation triggered by an immune response to otherwise harmless microorganisms in the sinus membranes.

20 Dec 2013

Top cancer centers lack policies to protect cancer patients' fertility

Infertility is consistently listed as one of the most distressing long-term side effects of cancer treatment for adolescents and young adults. Yet the leading National Cancer Institute-designated comprehensive cancer centers -- which should be leaders in fertility preservation -- aren't doing an adequate job of helping patients protect their fertility, reports a new Northwestern Medicine- study.

20 Dec 2013

FibroGen starts patient enrollment in FG-3019 Phase 2 study for idiopathic pulmonary fibrosis treatment

FibroGen, Inc., announced today that patient enrollment has started in a new Phase 2 clinical study of FG-3019 in patients who suffer from idiopathic pulmonary fibrosis.

20 Dec 2013

MicuRx announces initiation of global clinical development program for MRX-I compound

MicuRx Pharmaceuticals, Inc., a privately-held biopharmaceutical company developing next-generation antibiotics, today announced the initiation of a global clinical development program for its lead compound MRX-I, a novel oxazolidinone antibiotic for treatment of Gram-positive infections including methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci.

20 Dec 2013

UC Irvine scientists find that reprogramming of liver 'clock' may contribute to metabolic disorders

A high-fat diet affects the molecular mechanism controlling the internal body clock that regulates metabolic functions in the liver, UC Irvine scientists have found. Disruption of these circadian rhythms may contribute to metabolic distress ailments, such as diabetes, obesity and high blood pressure.

20 Dec 2013

Medical Condition News

Icahn School of Medicine at Mount Sinai joins NIH Stroke Trials Network

New MDA Endurance Program aims to find treatments and cures for muscle disease

Oramed reports positive results from ORMD-0801 pharmacokinetic study in type 1 diabetes patients

Auxilium seeks FDA approval for XIAFLEX sBLA to treat multiple Dupuytren's contracture cords concurrently

Study reveals that K-Ras gene mutations behave in ways that subvert normal mechanisms of cell death

Doctors should consider underlying inflammatory conditions when selecting anti-epilepsy drugs, say researchers

ESC presents results of pilot registry on management and treatment of AF in Europe

Coupling meditation-like practices with drug and behavior therapies more helpful in tackling addiction

New antibody could boost strength, muscle mass in patients with cancer and other diseases

Experimental drug inhibits BTK molecule in patients with chronic lymphocytic leukemia

Joint initiative aims to eradicate health disparities among communities of color in the U.S.

IQWiG reassesses vemurafenib for treatment of advanced melanoma

Amgen reports that Phase 3 DESCARTES study for high cholesterol meets primary endpoint

Parkinson's disease patients may find difficulties in recognizing emotions

Sugar-based gelators may provide alternatives to trans fats linked to obesity, heart disease, diabetes

Study supports mounting evidence that inflammation may be the cause of chronic rhinosinusitis

Top cancer centers lack policies to protect cancer patients' fertility

FibroGen starts patient enrollment in FG-3019 Phase 2 study for idiopathic pulmonary fibrosis treatment

MicuRx announces initiation of global clinical development program for MRX-I compound

UC Irvine scientists find that reprogramming of liver 'clock' may contribute to metabolic disorders

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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