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Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

A drug used to control Type II diabetes can help repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually to a paralysis, a vegetative state and death.

10 Jun 2013

Brain-training computer games may help restore memory and competency to forensic psychiatry patients

Brain-training computer games may help restore memory and competency to forensic psychiatry patients in state mental hospitals, researchers say.

10 Jun 2013

First Edition: June 10, 2013

Today's headlines include reports about President Barack Obama's efforts last week to urge uninsured people to sign up for the coverage that will soon become unavailable as a result of the health law.

10 Jun 2013

New non-invasive test measures methylation of SDC2 gene, detects 87% of colorectal cancer

The average 5-year survival for colorectal cancer (CRC) is less than 10% if metastasis occurs, but can reach 90% if detected early. A new non-invasive test has been developed that measures methylation of the SDC2 gene in tissues and blood sera.

10 Jun 2013

Common antidepressant medications may impair a form of learning, new report suggests

An interesting new report of animal research published in Biological Psychiatry suggests that common antidepressant medications may impair a form of learning that is important clinically.

10 Jun 2013

AVEO Oncology receives Complete Response letter from FDA for tivozanib NDA

AVEO Oncology today announced that it has received a Complete Response letter from the U.S. Food and Drug Administration informing the company that the FDA will not approve in its present form the New Drug Application for AVEO's investigational agent tivozanib for the treatment of patients with advanced renal cell carcinoma.

10 Jun 2013

Edge Therapeutics announces FDA acceptance of IND application for EG-1962

Edge Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products for acute, fatal or debilitating conditions, announced today that the U.S. Food and Drug Administration has accepted the Company's Investigational New Drug application for EG-1962, a novel bio-absorbable nimodipine microparticle formulation.

10 Jun 2013

Whitehead Institute researchers identify drug target for anemia

Researchers at Whitehead Institute have identified a protein that is the target of glucocorticoids, the drugs that are used to increase red blood cell production in patients with certain types of anemia, including those resulting from trauma, sepsis, malaria, kidney dialysis, and chemotherapy.

10 Jun 2013

Arthritis estimated to cost $33 billion annually to the Canadian economy

Siena Pacheco is five years old, and enjoys swimming and riding her bike. Sheila Stone has a few years on Siena, but she also enjoys swimming and cycling, and the kindergarten teacher insists she still has the spirit of a five-year-old.

10 Jun 2013

Poll reveals that half of Canadians are directly touched by stroke

More Canadians are surviving strokes due to advances in awareness and medical services but a new report by the Heart and Stroke Foundation reveals that more than one-third of Canadians mistakenly believe that the recovery period is limited to a few months.

10 Jun 2013

First consensus guidelines for use of neurostimulation in chronic pain

Recognizing that treatment of chronic pain can be confounding, the Neuromodulation Appropriateness Consensus Committee, an international group of more than 60 leading pain specialists, has created the first consensus guidelines for the use of neurostimulation in chronic pain.

10 Jun 2013

International experts formulate guidance for neuromodulation practitioners

An international panel of experts has formulated guidance for neuromodulation practitioners that reflects increasing recognition of the value of this growing field.

10 Jun 2013

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

10 Jun 2013

FDA panel loosens Avandia safety restrictions

Despite some concern over whether the diabetes drug Avandia can increase heart problems, an FDA panel Thursday loosened restrictions on how doctors can prescribe the drug.

10 Jun 2013

Nation's leading experts join forces to accelerate effective treatments for brain tumors

The nation's leading brain tumor and biotech industry experts again joined forces Friday, June 7, in a bid to accelerate more effective treatments for brain tumors and promote funding for the latest emerging therapies, as the Weill Cornell Brain and Spine Center and Voices Against Brain Cancer hosted its second annual Brain Tumor Biotech Summit.

10 Jun 2013

Cedars-Sinai opens Phase III clinical trial for patients with intestinal carcinoid cancer

Working to improve treatment and survivorship outcomes, the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute has opened a Phase III clinical trial of targeted radiation for patients with intestinal carcinoid cancer that has spread beyond the intestine.

10 Jun 2013

Drug regulators slow to pursue concerns about potential adverse effects of new diabetes drugs

The BMJ and Channel 4 Dispatches investigated and found that evidence suggesting potential harm from the drugs in industry studies has not been published.

10 Jun 2013

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

By applying light stimulation to highly specific neurons in the brain, the researchers managed to re-establish normal behaviour in mice that had beforehand presented pathological repetitive behaviour similar to that observed in human patients suffering from obsessive-compulsive disorders.

10 Jun 2013

Data emphasise need for comprehensive analysis of mtDNA in mitochondrial disease patients

French scientists have discovered that supposedly rare mutations in the mitochondria, the 'power plants' of human cells responsible for creating energy, account for more than 7% of patients with a mitochondrial disease manifesting itself as a respiratory deficiency.

10 Jun 2013

Scientists discover how Arc protein helps translate learning into memory

Scientists at the Gladstone Institutes have deciphered how a protein called Arc regulates the activity of neurons-providing much-needed clues into the brain's ability to form long-lasting memories. These findings, reported today in Nature Neuroscience, also offer newfound understanding as to what goes on at the molecular level when this process becomes disrupted.

10 Jun 2013

Medical Condition News

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

Brain-training computer games may help restore memory and competency to forensic psychiatry patients

First Edition: June 10, 2013

New non-invasive test measures methylation of SDC2 gene, detects 87% of colorectal cancer

Common antidepressant medications may impair a form of learning, new report suggests

AVEO Oncology receives Complete Response letter from FDA for tivozanib NDA

Edge Therapeutics announces FDA acceptance of IND application for EG-1962

Whitehead Institute researchers identify drug target for anemia

Arthritis estimated to cost $33 billion annually to the Canadian economy

Poll reveals that half of Canadians are directly touched by stroke

First consensus guidelines for use of neurostimulation in chronic pain

International experts formulate guidance for neuromodulation practitioners

Novel abnormalities in FGFR gene identified in a spectrum of cancers

FDA panel loosens Avandia safety restrictions

Nation's leading experts join forces to accelerate effective treatments for brain tumors

Cedars-Sinai opens Phase III clinical trial for patients with intestinal carcinoid cancer

Drug regulators slow to pursue concerns about potential adverse effects of new diabetes drugs

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

Data emphasise need for comprehensive analysis of mtDNA in mitochondrial disease patients

Scientists discover how Arc protein helps translate learning into memory

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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