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Scientists find that activating family of small protein could suppress liver malignancies

A team of scientists from the National University of Singapore (NUS) has found that activating a family of small protein, known as Rho, could suppress liver malignancies.

21 Oct 2013

Certain food and lifestyle habits can turn on or off expression of cancer related genes

Research performed at the Center of Research and Advanced Studies (Cinvestav) has identified that certain food and lifestyle habits can turn on or off the expression of cancer related genes.

21 Oct 2013

Hereditary high blood cholesterol overlooked and untreated worldwide

Hereditary high blood cholesterol leads to premature heart disease. It is overlooked and untreated virtually worldwide -- including in Europe. This is a major problem as the disease is dangerous for health. However, this disease is easy to diagnose and treat, according to the conclusion of a consensus report from the European Atherosclerosis Society.

21 Oct 2013

Genetic mutation found to restore translational balance in mice

In a biological quirk that promises to provide researchers with a new approach for studying and potentially treating Fragile X syndrome, scientists at the University of Massachusetts Medical School (UMMS) have shown that knocking out a gene important for messenger RNA (mRNA) translation in neurons restores memory deficits and reduces behavioral symptoms in a mouse model of a prevalent human neurological disease.

21 Oct 2013

Adolescents vaccination for pertussis linked with lower rates of infant hospitalizations

Widespread vaccination of adolescents for pertussis was associated with lower rates of infant hospitalizations for the respiratory infection than would have been expected had teens not been inoculated according to new research in Pediatrics.

21 Oct 2013

New small-molecule inhibitor shows promising results in drug-resistant melanoma, breast cancer

LEE011, a small-molecule inhibitor of cyclin-dependent kinases (CDK) 4/6 being developed by Novartis Oncology, showed promising results in drug-resistant melanoma and drug-resistant breast cancer when tested in combination with other targeted therapies, and based on these preclinical results, several phase I clinical trials were launched recently, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held October 19-23.

21 Oct 2013

Research: Learning mentally demanding skill likely to improve cognitive functioning

Older adults are often encouraged to stay active and engaged to keep their minds sharp, that they have to "use it or lose it." But new research indicates that only certain activities - learning a mentally demanding skill like photography, for instance - are likely to improve cognitive functioning.

21 Oct 2013

Study finds inherited GATA3 gene variation increases risk of developing pediatric leukemia

Research led by St. Jude Children's Research Hospital scientists has linked an inherited gene variation to a nearly four-fold increased risk of developing a pediatric acute lymphoblastic leukemia (ALL) subtype that is associated with a poor outcome.

21 Oct 2013

Clarified role of signal-relay proteins may help explain spread of cancer

Cell biologists at The Johns Hopkins University have teased apart two integral components of the machinery that causes cells to move. Their discovery shows that cellular projections, which act as hands to help a cell "crawl," are apparently always initiated by a network of message-relaying proteins inside the cell.

21 Oct 2013

Researchers identify key therapeutic target for cancers driven by KRAS protein

Patients with cancers driven by the protein KRAS, which are particularly hard to treat, may benefit from small molecules that attach to and disrupt the function of a KRAS-containing protein complex, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23.

20 Oct 2013

Pfizer announces top-line results from phase 3b studies with Lyrica Capsules

Pfizer Inc. (NYSE:PFE) announced top-line results from two phase 3b, placebo-controlled studies with Lyrica® (pregabalin) Capsules CV in patients with fibromyalgia (FM) and painful diabetic peripheral neuropathy (DPN), respectively.

19 Oct 2013

Tips to overcome feelings of discouragement or blues

Whether it is simply waking up on the wrong side of the bed or a bad week at work, many situations may trigger an onset of the blues. One University of Alabama at Birmingham mental health expert says feeling down is a form of depression and should be addressed.

19 Oct 2013

Research Institute receives Fast Track status for its gene therapy product for treatment of SMA

AveXis and BioLife, synthetic biology platform companies, today announced that The Research Institute at Nationwide Children's Hospital received Fast Track designation from the U.S. Food and Drug Administration for its scAAV9.CB.SMN gene therapy product for the treatment of spinal muscular atrophy (SMA).

19 Oct 2013

Phase 2b study of JAK3 inhibitor VX-509 shows improvement in people with active RA

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced 12-week results from an ongoing Phase 2b study of VX-509, an investigational oral, selective Janus kinase 3 (JAK3) inhibitor, dosed once or twice daily in people with active rheumatoid arthritis (RA) taking methotrexate

19 Oct 2013

Dentist offers advanced teeth whitening options

Los Angeles tooth whitening dentist, Dr. Kevin Sands, offers advanced teeth whitening options to help patients erase many years' worth of stains from even the most discolored teeth.

19 Oct 2013

RNA-based gene expression test potentially determine presence or absence of BRAF V600E mutation

Veracyte, Inc., a molecular diagnostics company pioneering the field of molecular cytology, today announced preliminary study results suggesting the potential for an RNA-based gene expression test to accurately detect the BRAF V600E gene mutation in thyroid nodule fine needle aspiration (FNA) samples.

19 Oct 2013

Levemir FlexTouch insulin pen receives approval from Health Canada for treatment of diabetes

Novo Nordisk today announced that Health Canada has approved Levemir® FlexTouch®, a disposable prefilled insulin pen containing Levemir® (insulin detemir). Levemir® FlexTouch® has been designed to improve ease of use for insulin administration and to help decrease barriers to good treatment adherence for Canadians living with type 1 and type 2 diabetes mellitus (diabetes).

19 Oct 2013

Wnt5A signaling pathway helps researchers determine who may respond to BRAF inhibitors

One of the challenges of understanding cancer is trying to determine the mechanisms that drive metastasis, or the process by which tumor cells are able to spread throughout the body.

19 Oct 2013

Study: Skin tanning gene linked to higher risk for testicular cancer in white men

A gene important in skin tanning has been linked to higher risk for testicular cancer in white men, according to a study led by scientists from the U.S. National Institutes of Health and the University of Oxford in England.

19 Oct 2013

Advaxis announces full exercise of over-allotment option granted to underwriters

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, today announced the full exercise of the over-allotment option granted to the underwriters to purchase an additional 862,500 shares of its common stock and warrants to purchase an additional 431,250 shares (15% of the shares and warrants sold in this offering), at a public offering price of $4.00 per share and $0.001 per warrant, respectively, in connection with its previously announced underwritten public offering of 5,750,000 shares of common stock, and warrants to purchase up to an aggregate of 2,875,000 shares of common stock, bringing the total gross proceeds from the offering to approximately $26,500,000, before deducting underwriting discounts and commissions and other offering expenses payable by Advaxis, Inc.

19 Oct 2013

Medical Condition News

Scientists find that activating family of small protein could suppress liver malignancies

Certain food and lifestyle habits can turn on or off expression of cancer related genes

Hereditary high blood cholesterol overlooked and untreated worldwide

Genetic mutation found to restore translational balance in mice

Adolescents vaccination for pertussis linked with lower rates of infant hospitalizations

New small-molecule inhibitor shows promising results in drug-resistant melanoma, breast cancer

Research: Learning mentally demanding skill likely to improve cognitive functioning

Study finds inherited GATA3 gene variation increases risk of developing pediatric leukemia

Clarified role of signal-relay proteins may help explain spread of cancer

Researchers identify key therapeutic target for cancers driven by KRAS protein

Pfizer announces top-line results from phase 3b studies with Lyrica Capsules

Tips to overcome feelings of discouragement or blues

Research Institute receives Fast Track status for its gene therapy product for treatment of SMA

Phase 2b study of JAK3 inhibitor VX-509 shows improvement in people with active RA

Dentist offers advanced teeth whitening options

RNA-based gene expression test potentially determine presence or absence of BRAF V600E mutation

Levemir FlexTouch insulin pen receives approval from Health Canada for treatment of diabetes

Wnt5A signaling pathway helps researchers determine who may respond to BRAF inhibitors

Study: Skin tanning gene linked to higher risk for testicular cancer in white men

Advaxis announces full exercise of over-allotment option granted to underwriters

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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