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Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Chronic granulomatous disease, or CGD, is a diverse group of inherited diseases in which certain cells of the immune system have difficulty forming reactive oxygen compounds, most importantly superoxide radicals. These are used by these white blood cells to kill certain bacteria.

3 Sep 2013

Implantation rate of CIEDs continues to rise in most European countries

Infections cause a lower proportion of lead extractions than expected, according to preliminary results from the ELECTRa Registry presented at ESC Congress 2013 today by Dr Maria Grazia Bongiorni from Italy.

3 Sep 2013

Apitope successfully completes ATX-MS-1467 Phase I trial in relapsing MS patients with positive results

Apitope, the drug discovery and development company focused on treating the underlying cause of autoimmune diseases, today announced completion with positive results of its second Phase I clinical trial of ATX-MS-1467.

3 Sep 2013

Prana's PBT2 drug recognised as one of the most promising treatments under development

Prana Biotechnology, a leading global developer of first-in-class treatments for neurodegenerative disease, is pleased to announce Elsevier Business Intelligence has named clinical drug PBT2 as one of the Top 10 Neuroscience Projects to Watch.

3 Sep 2013

Renin inhibitor aliskiren not effective in slowing progression of coronary atherosclerosis

Among patients with prehypertension and coronary artery disease, use of the renin (an enzyme secreted by the kidneys) inhibitor aliskiren, compared with placebo, did not result in improvement or slowing in the progression of coronary atherosclerosis, according to a study published by JAMA.

3 Sep 2013

Trypophobia: The most common phobia may occur as result of specific visual feature

Does the sight of soap bubbles, aerated chocolate or a lotus flower seed pod bring you out in a cold sweat and make you feel panicky? If so, you could be a sufferer of one of the most common phobias you have never heard of - trypophobia, or the fear of holes.

3 Sep 2013

Researchers develop first animal model simulating eye complications linked with Graves' disease

Researchers have developed the first animal model simulating the eye complications associated with the thyroid condition Graves' disease, a breakthrough that could pave the way for better treatments, according to a recent study accepted for publication in The Endocrine Society's journal Endocrinology.

3 Sep 2013

Omecamtiv mecarbil fails to achieve primary endpoint in phase II ATOMIC-AHF study

Omecamtiv mecarbil, a cardiac myosin-activator, did not achieve its primary efficacy endpoint in reducing dyspnoea (shortness of breath) in patients with acute heart failure, according to the results of the phase II ATOMIC-AHF (Acute Treatment with Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure) study.

3 Sep 2013

Study assesses relationship between BMI and CV events in hypertensive patients with diabetes

Low BMI is a risk factor for CVD in hypertensive patients with diabetes, according to research presented at the ESC Congress today by Dr Takanori Nagahiro from Japan. The findings provide evidence for an obesity paradox in hypertensive patients with glucose intolerance.

3 Sep 2013

Acacia Pharma raises $23.5 million in Series B financing

Acacia Pharma, a pharmaceutical company specialising in the development of drugs for supportive care, announces it has raised £15 million (~$23.5 million) in a Series B financing led by Fidelity Biosciences and Novo A/S.

3 Sep 2013

Researchers create specific tests to detect cancer biomarkers in patients with dermatomyositis

Researchers from major universities in the U.S. have developed specific tests to identify cancer biomarkers in patients with dermatomyositis-a systemic inflammatory disease associated with increased risk of malignancy.

3 Sep 2013

Women in their 40s and 50s are hospitalized more than twice for asthma attack

Asthma is a disease that mostly affects young boys and adult women. And according to a new study, women in their 40s and 50s with asthma are hospitalized more than twice as often as men in the same age group. The 10-year study is published in the September issue of Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI).

3 Sep 2013

Authors of new paper outline possible factors to identify metabolically healthy obesity

Metabolically healthy obesity – where an individual has a Body Mass Index of greater than 30 but does not appear to be at increased risk of the health complications usually associated with excess weight – has only been recently widely recognised by medical practitioners.

3 Sep 2013

Adhering to MedDi does not appear associated with time to clinical onset of HD

Adhering to a Mediterranean-type diet (MedDi) does not appear associated with the time to clinical onset of Huntington disease (phenoconversion), according to a study by Karen Marder, M.D., M.P.H., of Columbia University College of Physicians and Surgeons, New York, N.Y., and colleagues.

3 Sep 2013

New model to predict which patients are most likely to have severe kidney failure from rhabdomyolysis

Researchers from Brigham and Women's Hospital (BWH) have developed a risk score calculation that can help predict which patients with rhabdomyolysis (a condition that occurs due to muscle damage) may be at risk for the severe complication of kidney failure or death.

3 Sep 2013

PTSD in mothers linked with increased risk for child maltreatment

Posttraumatic stress disorder (PTSD) in mothers appears to be associated with an increased risk for child maltreatment beyond that associated with maternal depression, according to a study published by JAMA Pediatrics, a JAMA Network publication.

3 Sep 2013

Argininosuccinic aciduria (ASA) and gene therapy: an interview with Dr Julien Baruteau, UCL Institute for Women's Health, London

This rare genetic condition can theoretically affect patients at any age but symptoms are more often observed in childhood and even uncommonly during the first days of life.

2 Sep 2013

Study finds reduction in incidence of STEMI after smoking ban implemented in Switzerland

Second-hand smoke increases the risk of coronary artery disease and acute myocardial infarction. For this reason, health policies aimed at reducing tobacco consumption and public smoke exposure are strongly recommended.

2 Sep 2013

Women are 25% less likely to die post TAVI than men, says doctor

Dr Sherif said: "Earlier studies on the impact of gender on outcome after transcatheter aortic valve implantation (TAVI) have had conflicting results. A Canadian study reported in 641 consecutive patients that female sex is associated with a better long-term and short-term survival after TAVI.1 An Italian study of 305 high risk patients found no gender differences in composite safety and efficacy endpoints at 30 days and one year after TAVI."2

2 Sep 2013

TAVI is safe therapeutic option than redo cardiac surgery

Use of bioprosthetic heart valves has dramatically increased (from 18% in 1991 to 59% in 2003), mainly in older patients with comorbidities. This is due to the increased risk of bleeding complications associated with lifelong use of anticoagulation for mechanical prostheses.

2 Sep 2013

Medical Condition News

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Implantation rate of CIEDs continues to rise in most European countries

Apitope successfully completes ATX-MS-1467 Phase I trial in relapsing MS patients with positive results

Prana's PBT2 drug recognised as one of the most promising treatments under development

Renin inhibitor aliskiren not effective in slowing progression of coronary atherosclerosis

Trypophobia: The most common phobia may occur as result of specific visual feature

Researchers develop first animal model simulating eye complications linked with Graves' disease

Omecamtiv mecarbil fails to achieve primary endpoint in phase II ATOMIC-AHF study

Study assesses relationship between BMI and CV events in hypertensive patients with diabetes

Acacia Pharma raises $23.5 million in Series B financing

Researchers create specific tests to detect cancer biomarkers in patients with dermatomyositis

Women in their 40s and 50s are hospitalized more than twice for asthma attack

Authors of new paper outline possible factors to identify metabolically healthy obesity

Adhering to MedDi does not appear associated with time to clinical onset of HD

New model to predict which patients are most likely to have severe kidney failure from rhabdomyolysis

PTSD in mothers linked with increased risk for child maltreatment

Argininosuccinic aciduria (ASA) and gene therapy: an interview with Dr Julien Baruteau, UCL Institute for Women's Health, London

Study finds reduction in incidence of STEMI after smoking ban implemented in Switzerland

Women are 25% less likely to die post TAVI than men, says doctor

TAVI is safe therapeutic option than redo cardiac surgery

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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