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Restless legs syndrome and insomnia: a possible explanation

Johns Hopkins researchers believe they may have discovered an explanation for the sleepless nights associated with restless legs syndrome (RLS), a symptom that persists even when the disruptive, overwhelming nocturnal urge to move the legs is treated successfully with medication.

7 May 2013

Isis begins clinical study of ISIS-STAT3 in patients with metastatic liver cancer

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 1b/2a clinical study of ISIS-STAT3Rx in patients with advanced metastatic hepatocellular carcinoma (HCC).

7 May 2013

Janssen enrolls patients in expanded access program for mantle cell lymphoma

Janssen Research & Development, LLC (Janssen) today announced patients are now enrolling in a multicenter, open-label expanded access program (EAP) in the United States for the investigational oral Bruton's Tyrosine Kinase (BTK) inhibitor ibrutinib, which is being jointly developed by Janssen and Pharmacyclics, Inc.

7 May 2013

ECMO can be used on neonates with severe respiratory failure until lung transplantation, say scientists

Adults with end-stage respiratory failure and pulmonary hypertension requiring ECMO (extracorporeal membrane oxygenation) have been "bridged" toward lung transplantation with novel lung assist devices such as the Novalung.

7 May 2013

FDA warns over the use of sunlamp products that cause skin cancer

Today, the U.S. Food and Drug Administration issued a proposed order that, if finalized, would reclassify sunlamp products and require labeling to include a recommendation designed to warn young people not to use these devices.

7 May 2013

Biomedical engineers grow 3D human heart muscle that acts just like natural tissue

Duke University biomedical engineers have grown three-dimensional human heart muscle that acts just like natural tissue. This advancement could be important in treating heart attack patients or in serving as a platform for testing new heart disease medicines.

7 May 2013

Lower income, pregnant women may have increased risk for anemia

Lower income, urban women may be at increased risk for anemia during pregnancy if they live more than .25 miles, considered a "walking distance," from a healthy food source, according to a new study by researchers at Montefiore Medical Center.

7 May 2013

Breast milk might prevent premature babies from deadly intestinal condition

An ingredient that naturally occurs in breast milk might be used to prevent premature babies from developing a deadly intestinal condition that currently is largely incurable, according to researchers at the University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC in this week's online early edition of the Proceedings of the National Academy of Sciences.

7 May 2013

Anavex invited to submit funding application for Phase 2a trial of ANAVEX 2-73

Anavex Life Sciences Corp. ("Anavex") (OTCQB: AVXL) today announced that it has been invited to submit a full grant application to the Alzheimer's Drug Discovery Foundation ("ADDF") for a Phase 2a trial of ANAVEX 2-73.

7 May 2013

AADA urges FDA to prohibit the use and sale of indoor tanning devices for minors

The American Academy of Dermatology Association (AADA) is pleased that the U.S. Food and Drug Administration (FDA) has proposed changes to its regulation of tanning beds, including a strong recommendation against the use of tanning beds by minors under the age of 18.

7 May 2013

Scientists halt tumour development through genetic manipulation of cytoskeleton in fly tissues

Cancer is a complex disease, in which cells undergo a series of alterations, including changes in their architecture; an increase in their ability to divide, to survive and to invade new tissues or metastasis.

7 May 2013

Aileron Therapeutics concludes first-in-human study of ALRN-5281 Stapled Peptide drug

Aileron Therapeutics, Inc. today announced the completion of the first-in-human study of its lead Stapled Peptide drug, ALRN-5281, a proprietary, long-acting growth-hormone-releasing hormone (GHRH) agonist for treating orphan endocrine disorders, including adult growth hormone (GH) deficiency and human immunodeficiency virus (HIV) lipodystrophy, as well as broader patient populations involving a wide variety of metabolic/endocrine diseases.

7 May 2013

Study offers new hope to patients suffering from laminopathies

Laminopathies are hereditary diseases that affect mainly the muscle tissue. These diseases include for example Emery-Dreifuss Muscular dystrophy, dilated cardiomyopathy, limb-girdle muscular dystrophy and Hutchison-Gilford progeria syndrome.

7 May 2013

AUA and ASTRO release new guideline on adjuvant and salvage radiotherapy after prostatectomy

The American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA) are pleased to announce the publication of the joint guideline on radiation therapy after prostatectomy for patients with and without evidence of prostate cancer recurrence.

7 May 2013

American Pain Society to host Annual Scientific Meeting in New Orleans from May 8 to 11

The 32ed Annual Scientific Meeting of the American Pain Society will convene May 8-11 at the New Orleans Convention Center.

7 May 2013

New report highlights factors that contribute to asthma

There is still no cure for asthma, so for 22 million people in the U.S., this chronic disease continues to be a daily burden no matter where they live. But it's not just air pollution they should be worried about. Factors such as pollen, secondhand smoke – even high rates of poverty, a large uninsured population or a high number of ER visits – can be critical signs that certain cities and states are worse for families with asthma. It is especially true for people with severe asthma.

7 May 2013

Implantation of new mechanical heart valve reduces anticoagulation therapy in AVR patients

For more than 40 years, patients under 65 years of age requiring heart valve replacement have had to choose between a mechanical valve that offers life-long durability but requires aggressive warfarin anticoagulation or a biological (cow or pig) valve that will wear out in 10-20 years but does not require anticoagulation.

7 May 2013

Patients with faulty heart valves can benefit from Valve-in-Valve technique

When a biologic aortic valve prosthesis fails, the patient often faces a high risk valve replacement through repeat open heart surgery. A new technique, known as Valve-in-Valve, uses minimally invasive techniques to introduce a collapsible aortic heart valve into the damaged valve in order to restore function.

7 May 2013

Entremed reports patent issuance for its lead drug candidate ENMD-2076

EntreMed, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of a variety of cancers, today announced the issuance by the Chinese State Intellectual Property Office of Patent Certificate No. ZL 200680044656.7.

7 May 2013

New form of electroconvulsive therapy could prevent adverse cognitive side effects

Electroconvulsive therapy (ECT) is the most effective acute treatment for severe major depression. However, even with newer forms of ECT, there remains a significant risk of adverse cognitive effects, particularly memory problems.

7 May 2013

Medical Condition News

Restless legs syndrome and insomnia: a possible explanation

Isis begins clinical study of ISIS-STAT3 in patients with metastatic liver cancer

Janssen enrolls patients in expanded access program for mantle cell lymphoma

ECMO can be used on neonates with severe respiratory failure until lung transplantation, say scientists

FDA warns over the use of sunlamp products that cause skin cancer

Biomedical engineers grow 3D human heart muscle that acts just like natural tissue

Lower income, pregnant women may have increased risk for anemia

Breast milk might prevent premature babies from deadly intestinal condition

Anavex invited to submit funding application for Phase 2a trial of ANAVEX 2-73

AADA urges FDA to prohibit the use and sale of indoor tanning devices for minors

Scientists halt tumour development through genetic manipulation of cytoskeleton in fly tissues

Aileron Therapeutics concludes first-in-human study of ALRN-5281 Stapled Peptide drug

Study offers new hope to patients suffering from laminopathies

AUA and ASTRO release new guideline on adjuvant and salvage radiotherapy after prostatectomy

American Pain Society to host Annual Scientific Meeting in New Orleans from May 8 to 11

New report highlights factors that contribute to asthma

Implantation of new mechanical heart valve reduces anticoagulation therapy in AVR patients

Patients with faulty heart valves can benefit from Valve-in-Valve technique

Entremed reports patent issuance for its lead drug candidate ENMD-2076

New form of electroconvulsive therapy could prevent adverse cognitive side effects

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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