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Cardiomyocytes can now be made cheaply and abundantly in the laboratory

Cardiomyocytes, the workhorse cells that make up the beating heart, can now be made cheaply and abundantly in the laboratory.

29 May 2012

Bioengineers develop first structure to grow small human blood vessels

Mice and monkeys don't develop diseases in the same way that humans do. Nevertheless, after medical researchers have studied human cells in a Petri dish, they have little choice but to move on to study mice and primates. University of Washington bioengineers have developed the first structure to grow small human blood vessels, creating a 3-D test bed that offers a better way to study disease, test drugs and perhaps someday grow human tissues for transplant.

29 May 2012

Intensive glucose control associated with reduced risk of albuminuria

A review of data from seven clinical trials suggests that intensive glucose control is associated with reduced risk of microalbuminuria and macroalbuminuria (conditions characterized by excessive levels of protein in the urine usually resulting from damage to the filtering units of the kidneys), according to a report published in the May 28 issue of Archives of Internal Medicine, a JAMA Network publication.

29 May 2012

Simple changes in health behavior spur big and lasting results

Simply ejecting your rear from the couch means your hand will spend less time digging into a bag of chocolate chip cookies. That is the simple but profound finding of a new Northwestern Medicine study, which reports simply changing one bad habit has a domino effect on others. Knock down your sedentary leisure time and you'll reduce junk food and saturated fats because you're no longer glued to the TV and noshing. It's a two-for-one benefit because the behaviors are closely related.

29 May 2012

New technique more sensitive in detecting bone loss than X-ray method

Are your bones getting stronger or weaker? Right now, it's hard to know. Scientists at Arizona State University and NASA are taking on this medical challenge by developing and applying a technique that originated in the Earth sciences. In a new study, this technique was more sensitive in detecting bone loss than the X-ray method used today, with less risk to patients. Eventually, it may find use in clinical settings, and could pave the way for additional innovative biosignatures to detect disease.

29 May 2012

Heart-wall muscle fibers are locally arranged in a special ‘minimal surface’

A study led by researchers from McGill University provides new insights into the structure of muscle tissue in the heart - a finding that promises to contribute to the study of heart diseases and to the engineering of artificial heart tissue.

29 May 2012

Aerobic exercise improves vascular reactivity to nearly normal levels

Pre-diabetic patients who engage in regular aerobic exercise improve their vascular reactivity to nearly normal levels, even if no weight loss is achieved, according to research presented today at the American Association of Clinical Endocrinologists (AACE) 21st Annual Meeting & Clinical Congress in Philadelphia. Pre-diabetes is a condition that affects nearly one in every four Americans.

28 May 2012

Intensive wellness program addresses multiple aspects of diabetes care

An integrated wellness team approach to diabetes care is helping patients lower their prescription costs and improve their condition, according to research presented today at the American Association of Clinical Endocrinologists' (AACE) 21st Annual Scientific & Clinical Congress in Philadelphia.

28 May 2012

Positive results from Acacia Phase II APD421 study in prevention of post-operative nausea & vomiting

Acacia Pharma announces positive results from its Phase II study of APD421, in the prevention of post-operative nausea & vomiting (PONV).

28 May 2012

Preoperative opportunity to control blood glucoses

Patients with diabetes mellitus experience significantly higher rates of surgical and systemic complications, higher mortality and increased length of stay during hospitalization following 11 major elective procedures, according to research presented today at the American Association of Clinical Endocrinologists (AACE) 21st Annual Meeting & Clinical Congress in Philadelphia.

28 May 2012

Scientists develop super-sensitive test that could detect diseases earlier

Scientists have developed an ultra-sensitive test that should enable them to detect signs of a disease in its earliest stages, in research published today in the journal Nature Materials.

28 May 2012

New medicine can start and hasten healing of diabetic and other chronic sores

A unique new medicine that can start and hasten healing of diabetic and other chronic sores is being developed at Umeå University in Sweden. After several years of successful experimental research, it is now ready for clinical testing.

28 May 2012

Medivir initiates MIV-711 phase I trial in bone disorders

Medivir AB, a research-based pharmaceutical company focused on infectious diseases, announced today that a phase I clinical trial has been initiated with its investigational drug, MIV-711, a cathepsin K inhibitor for the treatment of bone disorders characterized by excessive bone resorption such as osteoporosis, osteoarthritis and bone metastases.

28 May 2012

Researchers develop tentative model for diagnosis of colon cancer

Researchers from the Universidad Politécnica de Madrid's Facultad de Informática, the Universidad del País Vasco, the Gaiker Technology Centre (Biscay) and the Hospital de Cruces in Barakaldo, have developed a tentative model for the diagnosis of colon cancer based on a biomarker panel.

28 May 2012

AngioPredict project to focus on patients with metastatic colorectal cancer

The Royal College of Surgeons in Ireland (RCSI) is leading an international team of scientists on a major research study which aims to predict colorectal cancer patients' response to the 'angiogenesis inhibitor' class of anti-cancer drug which prevents growth of tumour blood vessels. The study will facilitate a more focused therapeutic approach thus limiting side-effects in patients.

28 May 2012

New insight into immune-cell movement patterns

By pairing an intimate knowledge of immune-system function with a deep understanding of statistical physics, a cross-disciplinary team at the University of Pennsylvania has arrived at a surprising finding: T cells use a movement strategy to track down parasites that is similar to strategies that predators such as monkeys, sharks and blue-fin tuna use to hunt their prey.

28 May 2012

FDA approves Cipher’s Absorica to treat severe recalcitrant nodular acne

Cipher Pharmaceuticals Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved Absorica, Cipher's novel, patented brand formulation of the acne medication isotretinoin, for the treatment of severe recalcitrant nodular acne.

28 May 2012

Tβ4 offers both neurorestoration and neuroprotection after TBI

RegeneRx Biopharmaceuticals, Inc. reported that data showing that Thymosin beta 4 (Tβ4) "provides both neuroprotection and neurorestoration after traumatic brain injury (TBI)," was published in the current (May 2012) edition of the Journal of Neurosurgery, 116:1081-1092.

28 May 2012

Important heat safety tips from Pennsylvania Departments of Health and Aging

With hot temperatures and high humidity expected to make an early appearance in some parts of Pennsylvania this Memorial Day weekend, the Departments of Health and Aging are urging everyone to take simple steps to prevent serious heat-related illness or even death.

28 May 2012

Researchers develop new technique that converts stem cells into brain cells

A new technique that converts stem cells into brain cells has been developed by researchers at Lund University. The method is simpler, quicker and safer than previous research has shown and opens the doors to a shorter route to clinical cell transplants.

28 May 2012