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FDA grants fast track designation to Genervon Biopharmaceuticals for ALS drug GM604

In a huge victory for ALS sufferers, FDA granted Genervon Biopharmaceuticals a fast track designation for its first in class highly effective multi-target master regulator biotechnology drug GM604 for ALS. FDA said it met the necessary criteria.

27 Jun 2013

MorphoSys, Celgene agree to jointly develop MOR202 for patients with multiple myeloma

MorphoSys AG and Celgene Corporation today announced an agreement to jointly develop MOR202 globally and to co-promote MOR202 in Europe.

27 Jun 2013

Low-molecular-weight PAHs promote conditions for cancer growth

Tobacco smoke, diesel exhaust and oil combustion carry polycyclic aromatic hydrocarbons - PAHs that are known to cause cancer. But of these PAHs, the obviously dangerous high-molecular-weight PAHs like benzo[a]pyrene (BaP) have received the vast majority of research attention.

26 Jun 2013

Kiadis Pharma to receive innovation credit from AgentschapNL to conduct Phase II study for ATIR

Kiadis Pharma B.V., a clinical stage biopharmaceutical company developing treatments for blood cancers, announced today that it will receive an innovation credit of up to €3 million from AgentschapNL, a division of the Dutch Ministry of Economic Affairs, to support the Phase II clinical development of Kiadis Pharma's lead pipeline product, ATIR™

26 Jun 2013

Researchers say genetics and life experience independently protect against cognitive decline in MS

U.S. and Italian researchers have determined that brain reserve, as well as cognitive reserve, independently protects against cognitive decline in multiple sclerosis (MS). Their article, "Brain reserve and cognitive reserve in multiple sclerosis: What you've got and how you use it", was published in Neurology on June 11, 2013.

26 Jun 2013

Johns Hopkins students design device to reduce need for repeated breast cancer surgeries

When a breast tumor is detected, many women opt to have a lumpectomy, which is surgery designed to remove the diseased tissue while preserving the breast. But during this procedure, doctors cannot learn right away whether all of the cancerous tissue has been removed, with no microscopic signs that cancer cells were left behind.

26 Jun 2013

Survey finds at least 20% of Ontario adolescents had TBI in their lifetime

One in five adolescents surveyed in Ontario said they have suffered a traumatic brain injury that left them unconscious for five minutes or required them to be hospitalized overnight, a statistic researchers in Toronto say is much higher than previously thought.

26 Jun 2013

Researchers say hCNT1 protein may affect cancer cells physiology, apart from transport function

The protein hCNT1, which plays a major role in nucleoside transport, may have other biological functions that may affect cancer cells physiology, apart from their transport function. This is the main conclusion of the new scientific work published on the journal Cell Death and Disease.

26 Jun 2013

Immunohistochemistry could be a reliable and cost-effective diagnostic approach for lung cancer

ALK rearrangement has been demonstrated to be a potent oncogenic driver and a promising therapeutic target in non-small cell lung cancer (NSCLC). It defines a distinct molecular subset of NSCLC, in particular adenocarcinoma that can benefit by the treatment of ALK-inhibitors.

26 Jun 2013

Findings suggest BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin

In 2 large studies, the association between aspirin use and risk of colorectal cancer was affected by mutation of the gene BRAF, with regular aspirin use associated with a lower risk of BRAF-wild-type colorectal cancer but not with risk of BRAF-mutated cancer, findings that suggest that BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin, according to a study in the June 26 issue of JAMA.

26 Jun 2013

Prader-Willi syndrome results in dysregulation of circadian and metabolic genes

Researchers with the UC Davis MIND Institute and Agilent Laboratories have found that Prader-Willi syndrome - a genetic disorder best known for causing an insatiable appetite that can lead to morbid obesity - is associated with the loss of non-coding RNAs, resulting in the dysregulation of circadian and metabolic genes, accelerated energy expenditure and metabolic differences during sleep.

26 Jun 2013

Pretreatment PET staging of LS-SCLC associated with improved survival

Each year, 13 percent of all newly diagnosed lung cancer patients are diagnosed with small-cell lung cancer (SCLC). Approximately 39 percent of patients with SCLC are diagnosed with limited-stage disease, meaning the cancer is only present in one lung, but may have spread to lymph nodes or tissue between the lungs.

26 Jun 2013

Computerized brain-fitness program improves memory and language skills in older adults

UCLA researchers have found that older adults who regularly used a brain-fitness program on a computer demonstrated significantly improved memory and language skills.

26 Jun 2013

Quality of CPR may vary depending on EMS department or hospital administering it

The quality of CPR (cardiopulmonary resuscitation) you receive may vary, depending on the EMS department or hospital administering it, according to the American Heart Association.

26 Jun 2013

Eisai submits BELVIQ NDS with Health Canada

Arena Pharmaceuticals, Inc. announced today that Eisai Limited (based in Mississauga, Ontario), a subsidiary of Eisai Inc., has submitted a New Drug Submission for BELVIQ (lorcaserin HCl) with Health Canada.

26 Jun 2013

Verastem announces initiation of VS-4718 Phase 1 trial in patients with advanced cancer

Verastem, Inc., focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, announced the initiation of a Phase 1 trial of VS-4718, a novel, small molecule inhibitor of focal adhesion kinase, in patients with advanced cancer.

26 Jun 2013

Improving care for depression in low-income communities provides greater benefits: Study

Improving care for depression in low-income communities -- places where such help is frequently unavailable or hard to find -- provides greater benefits to those in need when community groups such as churches and even barber shops help lead the planning process, according to a new study.

26 Jun 2013

PLK1 crucial for proper functioning of cancer cells, researchers reveal

One of the main indicators for determining the activity of a tumour or cancer is cell division. Cancer cells divide more than other types and the genes and molecules involved in the process of division are, often, targets for identifying and treating certain types of cancer.

26 Jun 2013

Study explores analgesic activity of ceftriaxone in humans

A single dose of the antibiotic ceftriaxone given for antimicrobial prophylaxis prior to surgery enhanced patient pain thresholds after the procedure, according to a study published in The Journal of Pain, the peer review publication of the American Pain Society.

26 Jun 2013

Scientists examine molecular similarities in human and canine B-cell lymphoma

Humans and their pet dogs are close, so close that they both develop a type of cancer called diffuse large B-cell lymphoma. In humans it's the most common lymphoma subtype while in dogs, it's one of the most common cancers in veterinary oncology.

26 Jun 2013

Medical Condition News

FDA grants fast track designation to Genervon Biopharmaceuticals for ALS drug GM604

MorphoSys, Celgene agree to jointly develop MOR202 for patients with multiple myeloma

Low-molecular-weight PAHs promote conditions for cancer growth

Kiadis Pharma to receive innovation credit from AgentschapNL to conduct Phase II study for ATIR

Researchers say genetics and life experience independently protect against cognitive decline in MS

Johns Hopkins students design device to reduce need for repeated breast cancer surgeries

Survey finds at least 20% of Ontario adolescents had TBI in their lifetime

Researchers say hCNT1 protein may affect cancer cells physiology, apart from transport function

Immunohistochemistry could be a reliable and cost-effective diagnostic approach for lung cancer

Findings suggest BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin

Prader-Willi syndrome results in dysregulation of circadian and metabolic genes

Pretreatment PET staging of LS-SCLC associated with improved survival

Computerized brain-fitness program improves memory and language skills in older adults

Quality of CPR may vary depending on EMS department or hospital administering it

Eisai submits BELVIQ NDS with Health Canada

Verastem announces initiation of VS-4718 Phase 1 trial in patients with advanced cancer

Improving care for depression in low-income communities provides greater benefits: Study

PLK1 crucial for proper functioning of cancer cells, researchers reveal

Study explores analgesic activity of ceftriaxone in humans

Scientists examine molecular similarities in human and canine B-cell lymphoma

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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