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Researchers identify HNF1B gene that can increase risk of ovarian cancer

Researchers at Mayo Clinic Cancer Center have identified a novel gene that can contribute to a woman's susceptibility for developing ovarian cancer. Researchers identified the gene, called HNF1B, through large-scale analysis of more than 16,000 women with ovarian cancer and more than 26,000 healthy women.

28 Mar 2013

Study: Hormone-therapy-related breast cancer cells can be attacked by cancer therapies

More than 100 women per day die from breast cancer in the United States. The odds of developing breast cancer increase for women taking hormone replacement therapy to avoid the effects of menopause.

28 Mar 2013

Study indicates link between estrogen and body fat storage

Women tend to carry excess fat in their hips and thighs, while men tend to carry it on their stomachs. But after menopause, things start to change: many women's fat storage patterns start to resemble those of men.

28 Mar 2013

Study: New genetic variants may increase cancer risk

The European Collaborative Oncological Gen-Environmental Study (COGS) project, whose main goal is to decipher the complex genetic bases of breast, prostate and ovarian cancers, publishes today a total of 12 research articles in several prestigious journals, including Nature Genetics, Nature Communications, The American Journal of Human Genetics and PLOS Genetics.

28 Mar 2013

First Edition: March 28, 2013

Today's headlines include various stories about the health law's implementation at both the federal and state level.

28 Mar 2013

Phase 2 study of REOLYSIN meets primary endpoint in patients with squamous cell lung cancer

Oncolytics Biotech Inc. today announced that it has met the primary overall statistical endpoint in its U.S. Phase 2 single arm clinical trial in patients with squamous cell carcinoma of the lung using intravenous administration of REOLYSIN in combination with carboplatin and paclitaxel in patients with metastatic stage IIIB, or stage IV, or recurrent SCCLC who are chemotherapy naïve for their metastatic or recurrent cancer (REO 021).

28 Mar 2013

European Commission grants conditional marketing authorization for Pfizer's BOSULIF

Pfizer Inc. announced today that the European Commission has granted conditional marketing authorization for BOSULIF (bosutinib) in the European Union for the treatment of adult patients with chronic phase, accelerated phase and blast phase Philadelphia chromosome positive chronic myelogenous leukemia previously treated with one or more tyrosine kinase inhibitor(s) and for whom imatinib, nilotinib and dasatinib are not considered appropriate treatment options.

28 Mar 2013

Prostate cancer prognosis tables: an interview with Dr John B. Eifler, Brady Urological Institute of Johns Hopkins

Prostate cancer is the most common cancer in men. Despite many advances in diagnosis and treatment over the past two decades, it remains the second most common cause of cancer related death in men.

28 Mar 2013

Data shows efficacy of MANF in neuroprotection 6-hydroxydopamine rat models of Parkinson's disease

Amarantus BioScience, Inc., a biotechnology company discovering and developing treatments and diagnostics for diseases associated with neurodegeneration and apoptosis, today reported positive preclinical data for its lead therapeutic MANF in neuroprotection 6-hydroxydopamine (6-OHDA) rat models of Parkinson's disease.

28 Mar 2013

Mental-health system feeling the pinch of sequestration

Despite recent alarms to give mental health a more serious approach and to mobilize more funding to address a broken mental-health system across the country and in Minnesota, sequestration is here.

28 Mar 2013

KineMed renews research collaboration with Pfizer for advancement of novel diabetes pathways

KineMed Inc. today announced the renewal of a non-exclusive research collaboration with Pfizer Inc. for the advancement of novel approaches towards metabolic disease, in particular Type II Diabetes.

From Pfizer, Inc. 28 Mar 2013

Research findings could lead to improved treatment for neuropathic pain

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, says a key protein in Schwann cells performs a critical, perhaps overarching, role in regulating the recovery of peripheral nerves after injury.

28 Mar 2013

Neurological researchers study promising new treatment for deadly brain tumors

A promising new treatment for deadly brain tumors taken orally with minimal side effects is being studied by neurological researchers at Rush University Medical Center, Chicago.

28 Mar 2013

Navidea commences enrollment in NAV4694 Phase 2b study to detect erebral β-amyloid plaque

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced that enrollment has commenced in its Phase 2b, open-label, safety and efficacy positron emission tomography imaging study of [18F]NAV4694 for detection of cerebral β-amyloid plaque in subjects diagnosed with Mild Cognitive Impairment.

28 Mar 2013

FDA accepts Merck's BLA for investigational Timothy grass pollen AIT

Merck, known as MSD outside the United States and Canada, today announced that the Biologics License Application for its investigational Timothy grass pollen (Phleum pratense) allergy immunotherapy tablet has been accepted for review by the U.S. Food and Drug Administration.

28 Mar 2013

Environmental enrichment increases endogenous cell migration, facilitates functional repair

A team of Korean researchers investigated whether "environmental enrichment" can improve the neurobehavioral function of six week-old mice after transplantation of adipose-derived stem cells to treat hypoxic-ischemic brain injury, and found that brain repair (neurogenesis) was aided in some animals through exercise-induced fibroblast growth factor 2 (FGF2), a strong pro-angiogenic factor.

28 Mar 2013

IDIBELL signs agreement with Histocell to use patent for acute pulmonary diseases with stem cells

The Bellvitge Biomedical Research Institute has signed a licensing agreement with the Spanish biotech company Histocell to make use of a patent for the treatment of acute pulmonary diseases with mesenchymal stem cells.

28 Mar 2013

Kessler Foundation scientist awarded five-year grant to study predictors of memory decline in MS

The National Multiple Sclerosis Society awarded Victoria Leavitt, PhD, a $619,618 grant to study predictors of memory decline in MS. Dr. Leavitt, a scientist in Neuropsychology and Neuroscience Research at Kessler Foundation, will use functional magnetic resonance imaging to evaluate a brain marker with predictive value for memory decline.

28 Mar 2013

TSRI scientists awarded innovative grant to develop anti-smoking drug candidates

As part of an unprecedented national effort to develop new drugs to treat neurological disorders, scientists from the Florida campus of The Scripps Research Institute have been awarded an innovative grant from the National Institute of Neurological Disorders and Stroke to help people break their addiction to nicotine.

28 Mar 2013

Virginia G. Piper Cancer Center Clinical Trials successfully tests cabozantinib

The FDA has approved a thyroid cancer drug successfully tested at Virginia G. Piper Cancer Center Clinical Trials, a partnership of Scottsdale Healthcare and the Translational Genomics Research Institute.

28 Mar 2013

Medical Condition News

Researchers identify HNF1B gene that can increase risk of ovarian cancer

Study: Hormone-therapy-related breast cancer cells can be attacked by cancer therapies

Study indicates link between estrogen and body fat storage

Study: New genetic variants may increase cancer risk

First Edition: March 28, 2013

Phase 2 study of REOLYSIN meets primary endpoint in patients with squamous cell lung cancer

European Commission grants conditional marketing authorization for Pfizer's BOSULIF

Prostate cancer prognosis tables: an interview with Dr John B. Eifler, Brady Urological Institute of Johns Hopkins

Data shows efficacy of MANF in neuroprotection 6-hydroxydopamine rat models of Parkinson's disease

Mental-health system feeling the pinch of sequestration

KineMed renews research collaboration with Pfizer for advancement of novel diabetes pathways

Research findings could lead to improved treatment for neuropathic pain

Neurological researchers study promising new treatment for deadly brain tumors

Navidea commences enrollment in NAV4694 Phase 2b study to detect erebral β-amyloid plaque

FDA accepts Merck's BLA for investigational Timothy grass pollen AIT

Environmental enrichment increases endogenous cell migration, facilitates functional repair

IDIBELL signs agreement with Histocell to use patent for acute pulmonary diseases with stem cells

Kessler Foundation scientist awarded five-year grant to study predictors of memory decline in MS

TSRI scientists awarded innovative grant to develop anti-smoking drug candidates

Virginia G. Piper Cancer Center Clinical Trials successfully tests cabozantinib

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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