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Novel anti-cancer drug conjugates to be evaluated by Ablynx and Spirogen

Ablynx [Euronext Brussels: ABLX] and Spirogen Ltd. announce a research collaboration to evaluate the potential of a novel anti-cancer drug conjugate combining Spirogen's proprietary cytotoxic drugs, pyrrolobenzodiazepines (PBD), and associated linker technology, with Nanobodies® generated using Ablynx’s proprietary technology platform.

25 Feb 2013

PneumRx initiates RePneu LVRC pivotal study in severe emphysema

PneumRx, Inc., a leader in interventional pulmonology, announced the first U.S. patients treated with PneumRx's Lung Volume Reduction Coils (LVRCs) for severe emphysema.

25 Feb 2013

Ampio to initiate dose escalation run-in study for treatment of knee osteoarthritis

Ampio Pharmaceuticals, Inc. announced today that it's Phase III clinical study of Ampion™ for the treatment for osteoarthritis of the knee will include a dose-escalation run-in study as recommended by the FDA.

25 Feb 2013

Individuals with psychogenic disease do have brains that function differently

Psychogenic diseases, formerly known as 'hysterical' illnesses, can have many severe symptoms such as painful cramps or paralysis but without any physical explanation. However, new research from the University of Cambridge and UCL (University College London) suggests that individuals with psychogenic disease, that is to say physical illness that stems from emotional or mental stresses, do have brains that function differently.

25 Feb 2013

Researchers map complex interactions of proteins that control inflammation

Inflammatory response plays a major role in both health protection and disease generation. While the symptoms of disease-related inflammatory response have been know, scientists have not understood the mechanisms that underlie it.

25 Feb 2013

FDA alerts patients and health care providers of voluntary recall of Omontys by Affymax

The U.S. Food and Drug Administration is alerting health care providers and patients of a voluntary nationwide recall of all lots of Omontys Injection by Affymax, Inc., of Palo Alto, Calif., and Takeda Pharmaceuticals Company Limited, of Deerfield, Ill.

25 Feb 2013

Study shows how pseudogenes can regulate activity of PTEN cancer-related gene

Small stretches of DNA in the human genome are known as "pseudogenes" because, while their sequences are nearly identical to those of various genes, they have long been thought to be non-coding "junk" DNA.

25 Feb 2013

FDA approves Amneal’s generic Suboxone to treat opioid drug dependence

Amneal Pharmaceuticals, LLC, the 7th largest generic drug manufacturer in the U.S. market, has received U.S. FDA approval for one of the first generic versions of Suboxone sublingual tablets for maintenance treatment of opioid drug dependence.

25 Feb 2013

Researchers identify new pseudogene that regulates tumour-suppressing PTEN

Researchers at Karolinska Institutet in Sweden have identified a new so-called pseudogene that regulates the tumour-suppressing PTEN gene. They hope that this pseudogene will be able to control PTEN to reverse the tumour process, make the cancer tumour more sensitive to chemotherapy and to prevent the development of resistance.

25 Feb 2013

Systemic delivery of antisense oligonucleotides neutralizes mutant RNA toxicity in mice with DM1

By targeting the specific mutation that causes the hereditary neuromuscular disease myotonic dystrophy, it is possible to neutralize the mutant RNA toxicity and minimize or even eliminate the disabling symptoms of the disease.

25 Feb 2013

HIV epidemics and extra-couple relationships: an interview with Steve Bellan, University of Texas

The epicentre of the HIV pandemic is in sub-Saharan Africa, though prevalence of infection varies dramatically between countries for reasons not completely understood.

25 Feb 2013

Study confirms presence of four molecular classes of head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is the seventh most common form of cancer in the United States, but other than an association with the human papillomavirus, no validated molecular profile of the disease has been established.

25 Feb 2013

WUSTL to develop 3-D computer models of brain biomechanics to better understand TBI

Washington University in St. Louis engineering researchers have received a five-year, $2.25 million grant to better understand traumatic brain injuries in efforts to improve methods for prevention and treatment.

25 Feb 2013

Duke researchers focus on deadly math behind mutated genes and damaged cells that drive cancer

Two Duke researchers are focusing on the deadly mathematics behind the mutated genes and damaged cells that drive cancer.

25 Feb 2013

Researchers identify several genes associated with human neurological disorders

Scientists at the Marine Biological Laboratory (MBL) have identified several genes linked to human neurological disorders, including Alzheimer's disease, Parkinson's disease and spinal cord injury, in the sea lamprey, a vertebrate fish whose whole-genome sequence is reported this week in the journal Nature Genetics.

25 Feb 2013

Orphan, CU to develop enzyme replacement therapy for CBS-deficient homocystinuria

The University of Colorado (CU) has signed exclusive, worldwide licensing and collaboration agreements with rare-disease research-and-development firm Orphan Technologies Ltd to develop an enzyme replacement therapy for Cystathionine Beta-Synthase (CBS) -deficient homocystinuria, a rare, inherited metabolic disease that is often fatal at a young age.

25 Feb 2013

Researchers discover new way to accelerate mass spectrometer that identifies proteins

Researchers at the University of Wisconsin-Madison have found a new way to accelerate a workhorse instrument that identifies proteins. The high-speed technique could help diagnose cancer sooner and point to new drugs for treating a wide range of conditions.

25 Feb 2013

Scientists identify mechanosensitive cellular signaling pathway in myofibroblasts

Pulmonary fibrosis is a scarring or thickening of the lungs that causes shortness of breath, a dry cough, fatigue, chest discomfort, weight loss, a decrease in the ability of the lungs to transmit oxygen to the blood stream, and, eventually, heart failure.

24 Feb 2013

A good night's sleep can also help promote cardiovascular health

Cutting back on sodium and increasing physical activity are not the only ways to improve heart health - a good night's sleep can also help promote cardiovascular health. One expert at the University of Alabama at Birmingham (UAB) says not getting enough sleep can have harmful heart-health effects.

24 Feb 2013

Bayshore Community Hospital's Center for Bariatrics receives ASMBS designation

Bayshore Community Hospital is proud to announce that its Center for Bariatrics has earned the prestigious "Center of Excellence" designation by the American Society of Metabolic and Bariatric Surgery (ASMBS).

24 Feb 2013

Medical Condition News

Novel anti-cancer drug conjugates to be evaluated by Ablynx and Spirogen

PneumRx initiates RePneu LVRC pivotal study in severe emphysema

Ampio to initiate dose escalation run-in study for treatment of knee osteoarthritis

Individuals with psychogenic disease do have brains that function differently

Researchers map complex interactions of proteins that control inflammation

FDA alerts patients and health care providers of voluntary recall of Omontys by Affymax

Study shows how pseudogenes can regulate activity of PTEN cancer-related gene

FDA approves Amneal’s generic Suboxone to treat opioid drug dependence

Researchers identify new pseudogene that regulates tumour-suppressing PTEN

Systemic delivery of antisense oligonucleotides neutralizes mutant RNA toxicity in mice with DM1

HIV epidemics and extra-couple relationships: an interview with Steve Bellan, University of Texas

Study confirms presence of four molecular classes of head and neck squamous cell carcinoma

WUSTL to develop 3-D computer models of brain biomechanics to better understand TBI

Duke researchers focus on deadly math behind mutated genes and damaged cells that drive cancer

Researchers identify several genes associated with human neurological disorders

Orphan, CU to develop enzyme replacement therapy for CBS-deficient homocystinuria

Researchers discover new way to accelerate mass spectrometer that identifies proteins

Scientists identify mechanosensitive cellular signaling pathway in myofibroblasts

A good night's sleep can also help promote cardiovascular health

Bayshore Community Hospital's Center for Bariatrics receives ASMBS designation

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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