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FDA agrees to allow ADial to move forward with Phase III trial of AD04 for alcohol use disorder

ADial Pharmaceuticals, LLC, announced today that the U.S. Food and Drug Administration has agreed to allow ADial to move forward with its plan to initiate Phase III trials of AD04 as a treatment for alcohol use disorder in certain targeted genotypes population only.

19 Apr 2013

Targacept moving forward with Phase 2b study of TC-5619 for treatment of schizophrenia

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today announced that it has completed recruitment of patients in the Phase 2b study of TC-5619 as a treatment for negative symptoms and cognitive dysfunction in schizophrenia.

19 Apr 2013

Research shows how breakdowns in DNA copying process contribute to cancer

Research led by a scientist at the University of York has thrown new light on the way breakdowns in the DNA copying process inside cells can contribute to cancer and other diseases.

19 Apr 2013

Knee brace can improve symptoms, function for people with knee osteoarthritis

Wearing a knee brace has been shown to "significantly improve the pain and symptoms" of a type of osteoarthritis affecting the kneecap, according to a new study.

From The University of Manchester 19 Apr 2013

Excess glutamate drives schizophrenia in high-risk individuals

An excess of the brain neurotransmitter glutamate may cause a transition to psychosis in people who are at risk for schizophrenia, reports a study from investigators at Columbia University Medical Center published in the current issue of Neuron.

19 Apr 2013

Health disparities not connected to lack of exercise, Vanderbilt study finds

Health disparities between white and black adults in the South are not connected to a lack of exercise but more likely related to other factors such as access to health care, socioeconomic status and perhaps genetics, according to a Vanderbilt study published in the journal PLOS ONE.

19 Apr 2013

Researchers study new ways of taking advantage of caffeine's lethal effects on cancer cells

Researchers from the University of Alberta are abuzz after using fruit flies to find new ways of taking advantage of caffeine's lethal effects on cancer cells-results that could one day be used to advance cancer therapies for people.

19 Apr 2013

Research findings provide new hope for people suffering from dry eye disease

Natural lubricants play an important role in health, including a well-known effect to help prevent osteoarthritis in knee and ankle joints. However, much is still unknown about their role and function in other areas of the body.

19 Apr 2013

Elevated responsivity of reward regions in the brain increases risk for future substance use

Do people get caught in the cycle of overeating and drug addiction because their brain reward centers are over-active causing them to experience greater cravings for food or drugs? In a unique prospective study Oregon Research Institute senior scientist Eric Stice, Ph.D., and colleagues tested this theory, called the reward surfeit model.

19 Apr 2013

Tel Aviv University researcher reveals the missing link between brain patterns and Alzheimer's

Evidence indicates that the accumulation of amyloid-beta proteins, which form the plaques found in the brains of Alzheimer's patients, is critical for the development of Alzheimer's disease, which impacts 5.4 million Americans.

19 Apr 2013

FDA approval paves way for U-M to conduct Phase II trial of stem cell injections in ALS patients

For nearly two years, University of Michigan neurologist Eva Feldman , M.D., Ph.D. has led the nation's first clinical trial of stem cell injections in patients with the deadly degenerative disease known as amyotrophic lateral sclerosis, often called ALS or Lou Gehrig 's disease.

19 Apr 2013

Research shows English-speaking U.S. Hispanics less likely to engage in skin cancer prevention practices

Research from The Cancer Institute of New Jersey shows that U.S. Hispanics who speak English are less likely to engage in skin cancer prevention practices and more likely to put themselves at risk for skin cancer as compared to Spanish-speaking Hispanics who live in this country.

19 Apr 2013

Patient enrollment underway in Phase III trial program to evaluate amikacin inhalation solution

Bayer HealthCare Pharmaceuticals Inc. announced today that patient enrollment is underway in its global Phase III trial program to evaluate the efficacy and safety of adjunctive aerosolized BAY41-6551 versus aerosolized placebo in the treatment of intubated and mechanically ventilated patients with Gram-negative pneumonia receiving standard of care intravenous antibiotics.

19 Apr 2013

Researchers propose strategies for improving the anti-cancer effects of interferon

Interferons have antitumor activity and have been used to treat a variety of malignancies, including colorectal and ovarian cancers.

18 Apr 2013

New invasive tumor ablation technique provides hope for liver cancer patients

A new minimally invasive tumor ablation technique is providing hope for liver cancer patients who can't undergo surgery or thermal ablation, a study shows.

18 Apr 2013

CT imaging and serum LDH can predict survival in patients with metastatic melanoma

Combining CT imaging findings with baseline serum lactate dehydrogenase levels is showing promise as a way to predict survival in patients with metastatic melanoma being treated with anti-angiogenic therapy.

18 Apr 2013

Study shows long-term exposure to fine particle matter air pollution is associated with atherosclerosis

The association between road traffic and heart disease has been suggested in several studies. In 2012 a large prospective cohort study from Denmark showed that traffic noise was significantly associated with risk of heart attack - for every 10 decibel increase in noise exposure (either at the time of the attack or over the five years preceding it) there was a 12% increased risk.

18 Apr 2013

Research: Gene behind epilepsy syndrome could play a key role in other idiopathic epilepsies

Researchers at the University Department of Neurology at the MedUni Vienna have identified a gene behind an epilepsy syndrome, which could also play an important role in other idiopathic (genetically caused) epilepsies.

18 Apr 2013

Study: Shock wave-facilitated cell therapy improves outcomes in patients with chronic heart failure

Treatment that consisted of shock wave (procedure using high-dose ultrasound)-mediated preconditioning of the target heart tissue prior to administration of bone marrow-derived mononuclear cells was associated with significant, albeit modest improvement in left ventricular ejection fraction (a measure of how well the left ventricle of the heart pumps with each contraction) after 4 months in patients with chronic postinfarction heart failure, according to a study in the April 17 issue of JAMA.

18 Apr 2013

NCI investigators design genetically engineered mouse to study human lung squamous cell carcinoma

National Cancer Institute (NCI) investigators have designed a genetically engineered mouse for use in the study of human lung squamous cell carcinoma (SCC). SCC is a type of non-small cell lung carcinoma, one of the most common types of lung cancer, with a five-year survival rate of about 15 percent.

18 Apr 2013

Medical Condition News

FDA agrees to allow ADial to move forward with Phase III trial of AD04 for alcohol use disorder

Targacept moving forward with Phase 2b study of TC-5619 for treatment of schizophrenia

Research shows how breakdowns in DNA copying process contribute to cancer

Knee brace can improve symptoms, function for people with knee osteoarthritis

Excess glutamate drives schizophrenia in high-risk individuals

Health disparities not connected to lack of exercise, Vanderbilt study finds

Researchers study new ways of taking advantage of caffeine's lethal effects on cancer cells

Research findings provide new hope for people suffering from dry eye disease

Elevated responsivity of reward regions in the brain increases risk for future substance use

Tel Aviv University researcher reveals the missing link between brain patterns and Alzheimer's

FDA approval paves way for U-M to conduct Phase II trial of stem cell injections in ALS patients

Research shows English-speaking U.S. Hispanics less likely to engage in skin cancer prevention practices

Patient enrollment underway in Phase III trial program to evaluate amikacin inhalation solution

Researchers propose strategies for improving the anti-cancer effects of interferon

New invasive tumor ablation technique provides hope for liver cancer patients

CT imaging and serum LDH can predict survival in patients with metastatic melanoma

Study shows long-term exposure to fine particle matter air pollution is associated with atherosclerosis

Research: Gene behind epilepsy syndrome could play a key role in other idiopathic epilepsies

Study: Shock wave-facilitated cell therapy improves outcomes in patients with chronic heart failure

NCI investigators design genetically engineered mouse to study human lung squamous cell carcinoma

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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