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New study looks at increasing rates of melanoma in US children

With springtime temperatures and warm weather approaching, the inclination to spend time outdoors is a strong one - especially for children who have been cooped up all winter.

9 Apr 2013

Johns Hopkins researchers find how gout-linked genetic mutation contributes to disease

Johns Hopkins scientists have found out how a gout-linked genetic mutation contributes to the disease: by causing a breakdown in a cellular pump that clears an acidic waste product from the bloodstream.

9 Apr 2013

Researchers discover that fruit fly mutation holds clues for treating motor neuron diseases

A team of researchers, led by Marc Freeman, PhD, an early career scientist with the Howard Hughes Medical Institute and associate professor of neurobiology at the University of Massachusetts Medical School have discovered a gene in the fruit fly Drosophila melanogaster that, when mutant, blocks the self-destruction of damaged axons, which could hold clues to treating motor neuron diseases, such as amyotrophic lateral sclerosis.

9 Apr 2013

New study shows exposure to tobacco smoke could negatively impact adolescent kidney function

Exposure to tobacco smoke could negatively impact adolescent kidney function; this is according to a new study led by a team of researchers at the Johns Hopkins Bloomberg School of Public Health and the Johns Hopkins Children's Center.

9 Apr 2013

Transposons increase in abundance and activity in brains as they age

As the body ages, the physical effects are notable; wrinkles in the skin appear, physical exertion becomes harder. But there are also less visible processes going on. Inside aging brains there is another phenomenon at work, which may contribute to age-related brain defects.

9 Apr 2013

Scientist receives NIH grant to study genetic causes of autism spectrum disorders in African Americans

The National Institutes of Health has awarded Dr. Daniel Geschwind, director of the UCLA Center for Autism Research and Treatment, a five-year, $10 million grant to continue his research on the genetic causes of autism spectrum disorders and to expand his investigations to include the genetics of autism in African Americans.

9 Apr 2013

Increasing number of hours of sleep may reduce prevalence of adolescent obesity

Increasing the number of hours of sleep adolescents get each night may reduce the prevalence of adolescent obesity, according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania.

9 Apr 2013

New drug combination shows anti-cancer activity in patients with solid tumors and germline mutation

A novel combination of two drugs has shown anti-cancer activity in patients who had incurable solid tumors and carried a germline mutation in their BRCA genes, Dana-Farber Cancer Institute researchers are reporting at the American Association for Cancer Research annual meeting in Washington, April 6-10.

8 Apr 2013

Study evaluates efficacy of drug combinations in treating colorectal cancer

Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Once colorectal cancer has spread to other parts of the body, only 11 percent of patients will survive five years from the date of their diagnosis.

8 Apr 2013

Male smokers with low levels of serum bilirubin are at higher risk for lung cancer

Elevated levels of bilirubin in the blood get attention in the clinic because they often indicate that something has gone wrong with the liver. Now researchers have found that male smokers with low levels of the yellow-tinged chemical are at higher risk for lung cancer and dying from the disease.

8 Apr 2013

Antibody-guided drug shows promising activity in ovarian cancer patients with platinum drug-resistant disease

A new antibody-guided drug has shown promising activity in a phase I trial involving ovarian cancer patients with platinum drug-resistant disease, researchers from Dana-Farber Cancer Institute will report today at the annual meeting of the American Association for Cancer Research.

8 Apr 2013

Carnitine compound in red meat and energy drinks increases risk for cardiovascular disease

A compound abundant in red meat and added as a supplement to popular energy drinks has been found to promote atherosclerosis - or the hardening or clogging of the arteries - according to Cleveland Clinic research published online this week in the journal Nature Medicine.

8 Apr 2013

Migraine sufferers should undergo more formal experiments, says study

Women often point to stress, hormones, alcohol, or even the weather as possible triggers for their migraines. But a new study from Wake Forest Baptist Medical Center found that it is nearly impossible for patients to determine the true cause of their migraine episodes without undergoing formal experiments.

8 Apr 2013

Medications to treat arrhythmias may increase the risk of developing cancer

One of the most widely used medications to treat arrhythmias may increase the risk of developing cancer, especially in men and people exposed to high amounts of the drug.

8 Apr 2013

GE Healthcare releases next-generation sequencing assay for use in clinical trials

GE Healthcare announced today that Clarient Diagnostic Services, Inc., a GE Healthcare company, will begin offering a next-generation sequencing assay focused on solid tumor targets for use in clinical trials.

8 Apr 2013

Blood test reveals more gene mutations in cancer than traditional tumor biopsy

A new blood test revealed more of the gene mutations that sustain certain digestive-tract tumors than did a DNA analysis of a traditional tumor biopsy, Dana-Farber Cancer Institute investigators will report at a special symposium of the American Association for Cancer Research annual meeting in Washington, April 6-10.

8 Apr 2013

Researchers identify seven new gene loci linked to obesity

An international research team has identified seven new gene loci linked to obesity. Researchers were also able to show that the genetic mechanisms that cause extreme obesity are similar to those that cause milder forms of overweight and obesity.

8 Apr 2013

Preclinical data for potent IDO pathway inhibitor presented at AACR 2013 annual meeting

NewLink Genetics Corporation, a biopharmaceutical company primarily focused on discovering, developing and commercializing immunotherapeutic products in oncology, announced today that the company presented preclinical data for NLG919, a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor, at the American Association for Cancer Research 2013 annual meeting.

8 Apr 2013

Pancreatic Cancer Action Network researchers to participate in Rally for Medical Research

Researchers and advocates from the Pancreatic Cancer Action Network will join nearly 200 national organizations today in demonstrating their concern about the impact of sequestration on cancer research during the Rally for Medical Research at 11 AM on the steps of the Carnegie Library in Washington, D.C.

8 Apr 2013

FDA grants Breakthrough Therapy Designation for ibrutinib as monotherapy for CLL patients

Pharmacyclics, Inc. announced today that the U.S. Food and Drug Administration has granted an additional Breakthrough Therapy Designation for the investigational oral agent ibrutinib as monotherapy for the treatment of chronic lymphocytic leukemia or small lymphocytic lymphoma patients with deletion of the short arm of chromosome 17 (deletion 17p).

8 Apr 2013

Medical Condition News

New study looks at increasing rates of melanoma in US children

Johns Hopkins researchers find how gout-linked genetic mutation contributes to disease

Researchers discover that fruit fly mutation holds clues for treating motor neuron diseases

New study shows exposure to tobacco smoke could negatively impact adolescent kidney function

Transposons increase in abundance and activity in brains as they age

Scientist receives NIH grant to study genetic causes of autism spectrum disorders in African Americans

Increasing number of hours of sleep may reduce prevalence of adolescent obesity

New drug combination shows anti-cancer activity in patients with solid tumors and germline mutation

Study evaluates efficacy of drug combinations in treating colorectal cancer

Male smokers with low levels of serum bilirubin are at higher risk for lung cancer

Antibody-guided drug shows promising activity in ovarian cancer patients with platinum drug-resistant disease

Carnitine compound in red meat and energy drinks increases risk for cardiovascular disease

Migraine sufferers should undergo more formal experiments, says study

Medications to treat arrhythmias may increase the risk of developing cancer

GE Healthcare releases next-generation sequencing assay for use in clinical trials

Blood test reveals more gene mutations in cancer than traditional tumor biopsy

Researchers identify seven new gene loci linked to obesity

Preclinical data for potent IDO pathway inhibitor presented at AACR 2013 annual meeting

Pancreatic Cancer Action Network researchers to participate in Rally for Medical Research

FDA grants Breakthrough Therapy Designation for ibrutinib as monotherapy for CLL patients

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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