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Scientists identify role of GSK-3 alpha protein in promoting oncogenic KRAS function

While the mutated KRAS oncogene is associated with many cancers, it has not yet been successfully targeted by a therapeutic agent. Scientists are trying to find another way to target the gene by blocking signals from another protein downstream.

29 May 2013

Transplantation of human stem cells improves muscle function in rats used to model ALS

Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, causing death by respiratory failure.

29 May 2013

Residents need to help elderly neighbors, relatives keep safe during the heat wave

With the first heat wave of the season poised to descend on the Northeast, Dr. Thomas Cavalieri, a geriatrician and the dean of the University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine, is reminding residents to check on elderly neighbors and relatives who may not be aware of the dangers that come with hot weather.

29 May 2013

START team examines surgery-free treatment for people with knee osteoarthritis

Lindsay Tise is not the guy you would expect to see pumping iron at the gym. At 94 years old, he suffers from knee osteoarthritis, a debilitating yet common ailment for older Americans that makes physical activity both difficult and painful.

29 May 2013

New test to predict increased risk of death, hospitalization among kidney dialysis patients

Johns Hopkins scientists report that a 10-minute test for "frailty" first designed to predict whether the elderly can withstand surgery and other physical stress could be useful in assessing the increased risk of death and frequent hospitalization among kidney dialysis patients of any age.

29 May 2013

Digital chest tomosynthesis holds promise as first-line screening tool for lung cancer

Most lung cancers are detected when patients become symptomatic and have late-stage disease. However, recently, computed tomography creening for lung cancer has been reported to reduce lung cancer mortality.

29 May 2013

Research discovery may lead to development of new therapies for neurological disorders

For several years, the pharmaceutical industry has tried to develop drugs that target a specific neurotransmitter receptor in the brain, the NMDA receptor. This receptor is present on almost every neuron in the human brain and is involved in learning and memory. NMDA receptors also have been implicated in several neurological and psychiatric conditions such as Alzheimer's disease, Parkinson's disease, schizophrenia and depression.

29 May 2013

Unique omega-3 supplement improves lung function, reduces airway inflammation in asthmatics

An Indiana University study has found that a unique omega-3 supplement derived from the New Zealand green-lipped mussel significantly improved lung function and reduced airway inflammation in asthmatics who experience exercise-induced bronchoconstriction, also called exercise-induced asthma.

29 May 2013

Offspring of long-lived parents less prone to cancer, study reveals

The offspring of parents who live to a ripe old age are more likely to live longer themselves, and less prone to cancer and other common diseases associated with ageing, a study has revealed.

29 May 2013

Bay Pines VA Healthcare System to study effectiveness of 7-Keto compound in PTSD

The Bay Pines VA Healthcare System announced that it will begin a research study related to post-traumatic stress disorder. The study will focus on whether the use of a naturally occurring compound known as 7-Keto assists in the treatment of PTSD.

29 May 2013

Harmless genetic variations may team up to increase risk of schizophrenia, find researchers

Using a novel method of analyzing genetic variations in families, researchers at Johns Hopkins have found that individually harmless genetic variations affecting related biochemical processes may team up to increase the risk of schizophrenia.

29 May 2013

Valeant Pharmaceuticals receives Complete Response Letter from FDA for efinaconazole NDA

Valeant Pharmaceuticals International, Inc. today announced that it has received a Complete Response Letter from the U.S. Food and Drug Administration regarding its New Drug Application for efinaconazole for the treatment of onychomycosis.

28 May 2013

Research data on AMPYRA Extended Release Tablets to be presented at CMSC and ACTRIMS meeting

Acorda Therapeutics, Inc. will present new research data on AMPYRA (dalfampridine) Extended Release Tablets, 10 mg at the 5th Cooperative Meeting of the Consortium of Multiple Sclerosis Centers and Americas Committee for Treatment and Research in Multiple Sclerosis, being held in Orlando, FL, May 29 - June 1.

28 May 2013

Alkermes reports positive results from phase 1 study of ALKS 3831 for treatment of schizophrenia

Alkermes plc today presented positive results from a phase 1 study of ALKS 3831, a novel drug candidate for the treatment of schizophrenia, in an oral session at the 53rd Annual New Clinical Drug Evaluation Unit Meeting in Hollywood, Fla.

28 May 2013

New study shows childhood bullying increases risk of self-harming in later adolescence

A new study has proven that being bullied during childhood directly increases the likelihood of self- harm in late adolescence.

28 May 2013

Asfotase alfa gets Breakthrough Therapy designation from FDA for treatment of patients with HPP

Alexion Pharma International Sàrl, a subsidiary of Alexion Pharmaceuticals, Inc., today announced that the U.S. Food and Drug Administration has granted Breakthrough Therapy designation to asfotase alfa for the treatment of patients with hypophosphatasia (HPP) whose first signs or symptoms occurred prior to 18 years of age, including perinatal-, infantile-, and juvenile-onset forms of the disease.

28 May 2013

Parachute's Safe Kids Week 2013: Be alert. Be safe. Be aware of concussions

Twelve-year-old Nathan Fraser suffered a severe concussion during hockey practice in February 2012 when he tripped over a teammate diving for a puck and crashed head first into the ice and boards. Nathan's memory was wiped out, he lost five months of school and was so sensitive to sound and light he had to wear sunglasses and special earmuffs in his own home. After a long, slow recovery, Nathan and his family are now advocates for concussion prevention and awareness, a goal of Parachute's Safe Kids Week, May 27 to June 2.

28 May 2013

Sorrento Therapeutics, IGDRASOL announce publication of clinical data for Cynviloq and gemcitabine

Sorrento Therapeutics, Inc. and IGDRASOL announced today that clinical data for CynviloqTM, a non-biologic nanoparticle formulation of paclitaxel, plus gemcitabine was published for the upcoming Annual Meeting of the American Society of Clinical Oncology.

28 May 2013

Resolvins may help protect against cognitive decline after surgery

Resolvins are molecules naturally produced by the body from omega-3 fatty acids - a process that can be jumpstarted by common aspirin. In a new study, published in The FASEB Journal, researchers at Karolinska Institutet describe how resolvins could protect against the cognitive impairment that often affects recovery of surgical and critically ill patients.

28 May 2013

Frutarom reports increased demand for natural ingredient targeting urinary incontinence in adults

Frutarom Health, Switzerland, reports increased demand for Go-Less, its natural ingredient targeting urinary incontinence in adults.

28 May 2013

Medical Condition News

Scientists identify role of GSK-3 alpha protein in promoting oncogenic KRAS function

Transplantation of human stem cells improves muscle function in rats used to model ALS

Residents need to help elderly neighbors, relatives keep safe during the heat wave

START team examines surgery-free treatment for people with knee osteoarthritis

New test to predict increased risk of death, hospitalization among kidney dialysis patients

Digital chest tomosynthesis holds promise as first-line screening tool for lung cancer

Research discovery may lead to development of new therapies for neurological disorders

Unique omega-3 supplement improves lung function, reduces airway inflammation in asthmatics

Offspring of long-lived parents less prone to cancer, study reveals

Bay Pines VA Healthcare System to study effectiveness of 7-Keto compound in PTSD

Harmless genetic variations may team up to increase risk of schizophrenia, find researchers

Valeant Pharmaceuticals receives Complete Response Letter from FDA for efinaconazole NDA

Research data on AMPYRA Extended Release Tablets to be presented at CMSC and ACTRIMS meeting

Alkermes reports positive results from phase 1 study of ALKS 3831 for treatment of schizophrenia

New study shows childhood bullying increases risk of self-harming in later adolescence

Asfotase alfa gets Breakthrough Therapy designation from FDA for treatment of patients with HPP

Parachute's Safe Kids Week 2013: Be alert. Be safe. Be aware of concussions

Sorrento Therapeutics, IGDRASOL announce publication of clinical data for Cynviloq and gemcitabine

Resolvins may help protect against cognitive decline after surgery

Frutarom reports increased demand for natural ingredient targeting urinary incontinence in adults

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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