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Cerulean initiates CRLX101 Phase 2 study in extensive-stage small cell lung cancer

Cerulean Pharma Inc., a leader in developing dynamically tumor-targeted nanopharmaceuticals, today announced that the first patient has been dosed in a randomized Phase 2 study of its lead candidate, CRLX101, in patients with extensive-stage small cell lung cancer (SCLC) sensitive to first-line platinum-based chemotherapy.

31 Jan 2013

Northeast Ohio Medical University, CEL-SCI produce new investigational breast cancer vaccine

CEL-SCI Corporation announced that its longstanding collaboration with Northeast Ohio Medical University has produced a new investigational breast cancer vaccine which prevents and treats a HER-2/neu expressing breast cancer tumor in a mouse model of the disease.

31 Jan 2013

Adults should consume less than 5 g of salt and at least 3,510 mg of potassium per day: WHO

Adults should consume less than 2,000 mg of sodium, or 5 grams of salt, and at least 3,510 mg of potassium per day, according to new guidelines issued by the WHO. A person with either elevated sodium levels and low potassium levels could be at risk of raised blood pressure which increases the risk of heart disease and stroke.

31 Jan 2013

Interferon retreatment of chronic hepatitis C may be harmful

People with hepatitis C and chronic liver disease who relapsed or failed to respond to initial treatment are unlikely to improve on interferon retreatment. In fact, they may face an increased risk of dying sooner, and are likely to experience a variety of adverse effects, according to an updated systematic review published in The Cochrane Library.

31 Jan 2013

TB test offers rapid detection of TB and drug-resistant strains according to new study

A diagnostic test for tuberculosis (TB) can accurately and quickly detect both TB and drug-resistant strains, according to a new study. The authors of a new systematic review assessing the diagnostic accuracy of the Xpert® MTB/RIF test published in The Cochrane Library say their study can provide timely advice for clinicians and policymakers in countries where TB is a major public health problem.

31 Jan 2013

Selenium supplements do not reduce risk of developing heart disease according to current evidence

A systematic review published today in The Cochrane Library finds that in well-nourished adults current evidence does not support selenium for preventing heart disease.

31 Jan 2013

Cerebrolysin: a promising new treatment for dementia

Dementia patients may benefit from a promising new treatment called Cerebrolysin, according to the results of a systematic review published in The Cochrane Library. The authors brought together the most up-to-date evidence on Cerebrolysin as a treatment for vascular dementia.

31 Jan 2013

Congenital sight impairment cure grows closer

A cure for congenital sight impairment caused by lens damage is closer following research by scientists at Monash University.

31 Jan 2013

Teva terminates collaboration with CureTech

Teva Pharmaceutical Industries Ltd. announced today the termination of its collaboration with CureTech Ltd.

31 Jan 2013

Organizing the Nano World Cancer Day: A European multi-sites event in Paris, Braga and Berlin

In the framework of the World Cancer Day, the European Technology Platform of Nanomedicine (ETPN) and its partners will organize a European event on February the 1st on "How nanomedicine contributes to better cancer diagnostic and therapy". Similar and simultaneous events will be organized in France and Portugal, highlighting the importance of nanomedicine research for cancer on the European level.

31 Jan 2013

First payments awarded from 9/11 compensation fund

Fifteen first responders received payments from a federal fund set up to compensate people who were sickened by the Sept. 11 terrorist attacks. So far, fewer applications have been received by the fund than officials estimated they would receive.

31 Jan 2013

Being married and cohabiting reduces risk of heart attack in both men and women in all age groups

A large population-based study from Finland has shown that being unmarried increases the risk of fatal and non-fatal heart attack in both men and women whatever their age. Conversely, say the study investigators, especially among middle-aged couples, being married and cohabiting are associated with "considerably better prognosis of acute cardiac events both before hospitalization and after reaching the hospital alive".

31 Jan 2013

OncoEthix initiates OTX015 Phase I study in hematologic malignancies

OncoEthix, the Swiss-based specialist in oncology drug development, announces progress in its Phase I study of OTX015, a novel BET bromodomain inhibitor, with the first dosing of a patient.

31 Jan 2013

World Health Assembly's Executive Board concludes 132nd meeting

"The World Health Assembly's rotating Executive Board meets twice a year, and on 29 January concluded its 132nd meeting with what the WHO director general termed an 'unprecedented' amount of agenda items and documents," Intellectual Property Watch reports.

31 Jan 2013

Performing angiography and cardiac surgery on the same day increases risk of acute kidney injury

Performing heart surgery on the same day as angiography is now confirmed as a risk factor for acute kidney injury (AKI), and hospital policy limiting the practice for elective cardiac surgery has significantly reduced the rate of AKI, according to a study published in the February 2013 issue of The Annals of Thoracic Surgery.

31 Jan 2013

No added benefit from linagliptin in patients with type 2 diabetes

Linagliptin has been approved since August 2011 to improve blood glucose control in adults with type 2 diabetes. The assessment of the new dossier according to the German Act on the Reform of the Market for Medicinal Products (AMNOG) again showed that no added benefit of the drug over the appropriate comparator therapy (ACT) can be determined, because the pharmaceutical company has not submitted any relevant studies.

31 Jan 2013

UIC to determine whether exercise can shorten recovery time for stem cell transplant patients

Researchers at the University of Illinois at Chicago College of Nursing have received a four-year grant to determine whether exercise can shorten recovery time for patients who undergo high-dose chemotherapy and stem cell transplantation.

From Danaher 31 Jan 2013

Increasing age, male sex and adiposity risk factors for metabolic syndrome in children

Metabolic syndrome is more likely to affect children who are obese than overweight or non-overweight and who have other characteristics associated with the disorder, such as high blood pressure or insulin resistance. A new comprehensive and systematic review of the medical literature on metabolic syndrome in children that probed deeper to evaluate the risk associated with gender, ethnicity, and geography was published in Metabolic Syndrome and Related Disorders, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

31 Jan 2013

Review article highlights growing evidence for lasting impact of alcohol on the brain

Excessive alcohol use accounts for 4% of the global burden of disease, and binge drinking particularly is becoming an increasing health issue. A new review article published Cortex highlights the significant changes in brain function and structure that can be caused by alcohol misuse in young people.

31 Jan 2013

STS presents Earl Bakken Scientific Achievement Award to Stanford University professor

The Society of Thoracic Surgeons presented the Earl Bakken Scientific Achievement Award to D. Craig Miller, MD on Tuesday morning during the General Session at the STS 49th Annual Meeting.

31 Jan 2013

Medical Condition News

Cerulean initiates CRLX101 Phase 2 study in extensive-stage small cell lung cancer

Northeast Ohio Medical University, CEL-SCI produce new investigational breast cancer vaccine

Adults should consume less than 5 g of salt and at least 3,510 mg of potassium per day: WHO

Interferon retreatment of chronic hepatitis C may be harmful

TB test offers rapid detection of TB and drug-resistant strains according to new study

Selenium supplements do not reduce risk of developing heart disease according to current evidence

Cerebrolysin: a promising new treatment for dementia

Congenital sight impairment cure grows closer

Teva terminates collaboration with CureTech

Organizing the Nano World Cancer Day: A European multi-sites event in Paris, Braga and Berlin

First payments awarded from 9/11 compensation fund

Being married and cohabiting reduces risk of heart attack in both men and women in all age groups

OncoEthix initiates OTX015 Phase I study in hematologic malignancies

World Health Assembly's Executive Board concludes 132nd meeting

Performing angiography and cardiac surgery on the same day increases risk of acute kidney injury

No added benefit from linagliptin in patients with type 2 diabetes

UIC to determine whether exercise can shorten recovery time for stem cell transplant patients

Increasing age, male sex and adiposity risk factors for metabolic syndrome in children

Review article highlights growing evidence for lasting impact of alcohol on the brain

STS presents Earl Bakken Scientific Achievement Award to Stanford University professor

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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