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MCL-1 protein is vital for normal heart function, shows study

A study by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences and the Department of Pharmacology at the University of California, San Diego, shows that a protein called MCL-1, which promotes cell survival, is essential for normal heart function.

18 Jun 2013

New CREHST program aims to expose students to clinical aspect of cancer research

Building off the success of its Continuing Umbrella for Research Education Program that encourages underrepresented minority undergraduate and high school students to pursue careers in healthcare, the Cancer Institute of New Jersey is offering a related program focusing on clinical research.

18 Jun 2013

Vitamin D deficiency can increase asthma and allergy risk in obese children and teenagers

One reason why obese children and teenagers are more likely to have hard-to-control asthma and allergies may be vitamin D deficiency, a new study finds. Results of the study will be presented Tuesday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

Targeting SALL4 protein with druglike molecules could halt tumor growth, say researchers

Harvard Stem Cell Institute researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity.

18 Jun 2013

State highlights: States urge using life insurance for long-term care

State lawmakers are encouraging elderly residents to use life insurance as a way to pay for long-term care -- and lower the Medicaid tab in the process. The strategy marks a tacit endorsement of so-called life settlements, a practice in which policyholders sell their policies at a discount in the secondary market and the buyer takes over premiums and consequently collects the death benefit (Greene, 6/16).

18 Jun 2013

AtriCure's Bipolar RF Ablation System shows promising results in persistent Afib patients

A leading German cardiovascular heart center reported promising mid-term results for the surgical treatment of persistent atrial fibrillation during last week's International Society for Minimally Invasive Cardiothoracic Surgery meeting being held in Prague, Czech Republic.

18 Jun 2013

MGH researchers discover CNVs in members of 10 families with early-onset Alzheimer's

Although a family history of Alzheimer's disease is a primary risk factor for the devastating neurological disorder, mutations in only three genes - the amyloid precursor protein and presenilins 1 and 2 - have been established as causative for inherited, early-onset Alzheimer's, accounting for about half of such cases.

18 Jun 2013

Researchers identify two proteins that never before linked to alertness, sleep-wake balance

The quality of wakefulness affects how quickly a mammal falls asleep, UT Southwestern Medical Center researchers report in a study that identifies two proteins never before linked to alertness and sleep-wake balance.

18 Jun 2013

Scientists show how gastric bypass surgery restores some properties of nerve cells

Understanding how gastric bypass surgery changes the properties of nerve cells that help regulate the digestive system could lead to new treatments that produce the same results without surgery, according to Penn State College of Medicine scientists, who have shown how surgery restores some properties of nerve cells that tell people their stomachs are full.

18 Jun 2013

Vercise DBS System shows improvement in motor scores for patients with Parkinson's disease

Patients with Parkinson's disease using the Boston Scientific Corporation Vercise DBS (deep brain stimulation) System showed a significant improvement in motor scores according to interim data from the VANTAGE DBS study.

18 Jun 2013

TWi Biotechnology completes patient enrollment in phase II trial of AC-201 for Gout Flare Prophylaxis

TWi Biotechnology, Inc. announced that it has completed the patient enrollment in a phase II trial of AC-201 for Gout Flare Prophylaxis during urate-lowering therapy. This randomized, double-blind, placebo-controlled Phase II study is conducted in 8 major medical centers in Taiwan.

18 Jun 2013

Vanda presents additional data from tasimelteon Phase III studies at ENDO 2013

Vanda Pharmaceuticals Inc. presented additional data today at ENDO 2013, the Endocrine Society's 95th Annual Meeting, demonstrating that tasimelteon can entrain (synchronize) both melatonin and cortisol rhythms.

18 Jun 2013

Santarus, Pharming Group announce FDA acceptance of RUCONEST BLA

Santarus, Inc. and Pharming Group NV today announced that the U.S. Food and Drug Administration has accepted for filing the Biologics License Application for the investigational drug RUCONEST (recombinant human C1 esterase inhibitor) 50 IU/kg.

18 Jun 2013

Researchers to study benefits, side effects of four widely used therapies in adults with type 2 diabetes

UT Southwestern Medical Center researchers are seeking 150 adults with type 2 diabetes to take part in the local arm of a major national clinical trial that will compare benefits and side effects of four widely used therapies to lower blood-sugar levels.

18 Jun 2013

Texas passes legislation to prohibit minors under 18 from indoor tanning

Texas has joined California, Vermont, Oregon, and Nevada by passing legislation that prohibits minors under the age of 18 from indoor tanning. This announcement comes shortly after the U.S. Food and Drug Administration proposed stricter regulations on indoor tanning beds, as well as a strong recommendation against the use of tanning beds by minors under the age of 18.

18 Jun 2013

Two MRI measurements of abdominal aorta associated with future cardiovascular events

In a study of more than 2,000 adults, researchers found that two MRI measurements of the abdominal aorta - the amount of plaque in the vessel and the thickness of its wall - are associated with future cardiovascular events, such as a heart attack or stroke. Results of the study are published online in the journal Radiology.

18 Jun 2013

Researchers use patient-specific stem cells to correct deficient insulin-producing cells

A team from the New York Stem Cell Foundation Research Institute and the Naomi Berrie Diabetes Center of Columbia University has generated patient-specific beta cells, or insulin-producing cells, that accurately reflect the features of maturity-onset diabetes of the young.

18 Jun 2013

Concerns raised about disproportionate impact of changes in hospital payment methods

Teaching hospitals with a higher intensity of physician-training activity achieve lower mortality rates, but higher hospitalization readmission rates for key medical diagnoses, reports a study in the July issue of Medical Care, published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

18 Jun 2013

New study identifies possible treatment to block deposition of calcium in arterial wall

HGPS is a rare genetic disease that affects one in every 4-8 million births. The disease is caused by a spontaneous mutation in one of the two copies (alleles) of the gene LMNA, which codes for lamin A, a protein important for the integrity and function of the envelope surrounding the cell nucleus. The mutation causes incorrect processing of the messenger RNA for lamin proteins, resulting in the synthesis of an anomalous protein, called progerin.

18 Jun 2013

HPV antibodies may help identify individuals at increased risk of HPV-related oropharynx cancer

Researchers have found that antibodies against the human papillomavirus (HPV) may help identify individuals who are at greatly increased risk of HPV-related cancer of the oropharynx, which is a portion of the throat that contains the tonsils.

18 Jun 2013

Medical Condition News

MCL-1 protein is vital for normal heart function, shows study

New CREHST program aims to expose students to clinical aspect of cancer research

Vitamin D deficiency can increase asthma and allergy risk in obese children and teenagers

Targeting SALL4 protein with druglike molecules could halt tumor growth, say researchers

State highlights: States urge using life insurance for long-term care

AtriCure's Bipolar RF Ablation System shows promising results in persistent Afib patients

MGH researchers discover CNVs in members of 10 families with early-onset Alzheimer's

Researchers identify two proteins that never before linked to alertness, sleep-wake balance

Scientists show how gastric bypass surgery restores some properties of nerve cells

Vercise DBS System shows improvement in motor scores for patients with Parkinson's disease

TWi Biotechnology completes patient enrollment in phase II trial of AC-201 for Gout Flare Prophylaxis

Vanda presents additional data from tasimelteon Phase III studies at ENDO 2013

Santarus, Pharming Group announce FDA acceptance of RUCONEST BLA

Researchers to study benefits, side effects of four widely used therapies in adults with type 2 diabetes

Texas passes legislation to prohibit minors under 18 from indoor tanning

Two MRI measurements of abdominal aorta associated with future cardiovascular events

Researchers use patient-specific stem cells to correct deficient insulin-producing cells

Concerns raised about disproportionate impact of changes in hospital payment methods

New study identifies possible treatment to block deposition of calcium in arterial wall

HPV antibodies may help identify individuals at increased risk of HPV-related oropharynx cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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