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EETs promote primary tumor growth and metastasis in mouse models of cancer

Drugs that enhance levels of small molecules derived naturally in the body from a major component of animal fats (small molecules known as epoxyeicosatrienoic acids [EETs]) are currently in clinical trials for the treatment of high blood pressure and diabetes.

20 Dec 2011

Impax commences IPX159 Phase IIb trial in Restless Legs Syndrome

Impax Pharmaceuticals, the branded products division of Impax Laboratories, Inc., announced that it has initiated a Phase IIb trial of its drug candidate IPX159 in patients with moderate to severe Restless Legs Syndrome.

20 Dec 2011

ESC welcomes the US study that explores PCI readmissions

The European Society of Cardiology (ESC) welcomes the spotlight that a US study has placed on the importance of measuring rates of rehospitalisation following percutaneous coronary intervention (PCI) procedures.

20 Dec 2011

Gene therapy may promote growth of hair cells in inner ear

Normal hearing depends on the presence of healthy hair cells in the inner ear. Gene therapy has the potential to slow the loss of hair cells and promote the growth of hair cells that have already been damaged.

20 Dec 2011

Viewpoints: Is Wyden-Ryan Medicare plan a game changer?; The GOP and the individual mandate

In the maelstrom of dysfunction and partisanship better known as the 112th Congress, it is always surprising and gratifying when lawmakers from opposing parties manage to work together. That is particularly true when their collaboration involves an issue as politically charged and substantively complex as Medicare. So we begin by congratulating Sen. Ron Wyden (D-Ore.) and Rep. Paul Ryan (R-Wis.) for having the tenacity to try again, with a revamped version of Medicare reform unveiled last week.

20 Dec 2011

Smoking in women associated with skin cancer: Study

A new study has found a link between tobacco use and skin cancer especially in women. The study found that women who had squamous cell skin cancer were more likely to have smoked than those who were free from the disease. And those who smoked at least 20 years were twice as likely to develop squamous cell skin cancer - a less aggressive form of skin cancer as melanoma.

19 Dec 2011

Phase I clinical study of Selexys SelG1 for sickle cell disease completed

Selexys Pharmaceuticals announced today that it has completed a Phase I clinical study of its lead compound SelG1, an antibody specific for the pro-inflammatory cell adhesion molecule P-selectin.

19 Dec 2011

Individualised approach to cancer medicine considering genetic variations

A new cancer research centre established at the University of Adelaide will focus on treatment options tailored to the individual, taking into account DNA and genetic variations between people.

19 Dec 2011

Exactech commences clinical trial to evaluate new cartilage repair technology

Exactech, Inc., a developer and producer of bone and joint restoration products for hip, knee, shoulder, spine and biologic materials announced today it has initiated a prospective, randomized, multi-center, clinical trial to evaluate the safety and effectiveness of a new cartilage repair technology.

19 Dec 2011

UCL awarded 20M grant to establish The Leonard Wolfson Experimental Neurology Centre

A new centre dedicated to the understanding and treatment of neurodegenerative diseases will be established at UCL following the award of a -20million grant from the Wolfson Foundation, it was announced today.

19 Dec 2011

Second-hand smoke exposure during childhood associated with aspirin-exacerbated respiratory disease

Need another reason to keep your New Year's resolution to stop smoking? A first-of-its-kind study found adults with aspirin-exacerbated respiratory disease were more than three times as likely to have been exposed to second-hand smoke during childhood as those without the condition.

19 Dec 2011

Studies confirm potential of EarlySense system as risk assessment tool for preventing pressure ulcers

EarlySense, a market leader in proactive patient care solutions, announced today post regulatory approval clinical and interventional study results further confirming the EarlySense contact-free patient monitoring system's high value as a risk assessment tool for preventing pressure ulcers.

19 Dec 2011

Lixte's LB-205 shows therapeutic potential against Gaucher disease

An article in the early edition (December 12, 2011) of the Proceedings of the National Academy of Sciences USA, reported that Lixte's investigational drug, LB-205, was shown to have therapeutic potential in a laboratory model of Gaucher disease.

19 Dec 2011

ALS TDI, Biogen Idec and UCB enter agreement to study anti-CD40L antibody for ALS

The ALS Therapy Development Institute today announced a research agreement with Biogen Idec and UCB Pharma SA to investigate the use of an anti-CD40L antibody as a potential therapy for Amyotrophic Lateral Sclerosis, also known as Lou Gehrig's or Motor Neuron Disease.

19 Dec 2011

Alkermes commences ALKS 9070 phase 3 clinical trial for schizophrenia

Alkermes plc today announced the initiation of a phase 3 clinical trial of ALKS 9070 for the treatment of schizophrenia. ALKS 9070, a proprietary Alkermes molecule, is designed to provide patients with once-monthly dosing of a medication that, once in the body, converts into aripiprazole, a molecule that is commercially available under the name ABILIFY for the treatment of a number of central nervous system disorders.

19 Dec 2011

GSK initiates rhACE2 phase IIa study for Acute Lung Injury

APEIRON Biologics AG announced today that GlaxoSmithKline, exclusive, worldwide licensee for Apeiron's new investigational recombinant human Angiotensin Converting Enzyme 2 (rhACE2, name: GSK2586881, formerly APN01), has initiated a phase IIa study in patients suffering from Acute Lung Injury.

19 Dec 2011

Zalicus commences Z944 Phase 1 clinical trial for treatment of acute and inflammatory pain

Zalicus Inc. a biopharmaceutical company that discovers and develops novel treatments for patients suffering from pain and immuno-inflammatory diseases, today announced the initiation of a Phase 1 clinical trial evaluating the pharmacokinetics and safety of Z944, a novel oral T-type calcium channel blocker with demonstrated preclinical potential for the treatment of acute and inflammatory pain.

19 Dec 2011

Soybean compounds can increase effectiveness of radiation treatment for lung cancer

A Wayne State University researcher has shown that compounds found in soybeans can make radiation treatment of lung cancer tumors more effective while helping to preserve normal tissue.

19 Dec 2011

IGN joins BCCA Genome Science Center

Illumina, Inc. today announced that the British Columbia Cancer Agency's (BCCA) Genome Science Center has joined the Illumina Genome Network (IGN). IGN is designed to link researchers needing large-scale whole human genome sequencing with leading institutions that provide this application as a service using industry-leading Illumina sequencing platforms.

19 Dec 2011

Diseases of the Colon & Rectum publishes results from Pacira's EXPAREL Phase 3 trial

Pacira Pharmaceuticals, Inc. today announced the publication of data from a placebo-controlled, pivotal Phase 3 trial of EXPAREL (bupivacaine liposome injectable suspension), a non-opioid local analgesic that was recently approved by the U.S. Food and Drug Administration (FDA) for administration into the surgical site to produce postsurgical analgesia.

19 Dec 2011

Medical Condition News

EETs promote primary tumor growth and metastasis in mouse models of cancer

Impax commences IPX159 Phase IIb trial in Restless Legs Syndrome

ESC welcomes the US study that explores PCI readmissions

Gene therapy may promote growth of hair cells in inner ear

Viewpoints: Is Wyden-Ryan Medicare plan a game changer?; The GOP and the individual mandate

Smoking in women associated with skin cancer: Study

Phase I clinical study of Selexys SelG1 for sickle cell disease completed

Individualised approach to cancer medicine considering genetic variations

Exactech commences clinical trial to evaluate new cartilage repair technology

UCL awarded 20M grant to establish The Leonard Wolfson Experimental Neurology Centre

Second-hand smoke exposure during childhood associated with aspirin-exacerbated respiratory disease

Studies confirm potential of EarlySense system as risk assessment tool for preventing pressure ulcers

Lixte's LB-205 shows therapeutic potential against Gaucher disease

ALS TDI, Biogen Idec and UCB enter agreement to study anti-CD40L antibody for ALS

Alkermes commences ALKS 9070 phase 3 clinical trial for schizophrenia

GSK initiates rhACE2 phase IIa study for Acute Lung Injury

Zalicus commences Z944 Phase 1 clinical trial for treatment of acute and inflammatory pain

Soybean compounds can increase effectiveness of radiation treatment for lung cancer

IGN joins BCCA Genome Science Center

Diseases of the Colon & Rectum publishes results from Pacira's EXPAREL Phase 3 trial

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