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Proposing standards and guidelines for Rett syndrome research

There is an urgent need for new drugs to treat Rett syndrome, a rare and severe neurological disease mainly affecting girls. A bottleneck in drug development for this syndrome is a lack of clarity at the level of preclinical research. Key researchers in this field now tackle this issue, proposing standards and guidelines for Rett syndrome research, in an Open Access review article published on Oct. 31, 2012 in Disease Models & Mechanisms (DMM).

1 Nov 2012

Study finds how effective healthcare can reduce toll from major diseases like stroke, cancer

Wide differences in death rates from disease still persist throughout England - but effective healthcare can help to reduce these inequalities, a new study has discovered.

1 Nov 2012

Experimental HIV test might help improve diagnosis, treatment in developing countries

"Scientists have come up with a test for the virus that causes AIDS that is 10 times more sensitive and a fraction of the cost of existing methods, offering the promise of better diagnosis and treatment in the developing world," Reuters reports.

1 Nov 2012

Single dose of etanercept can improve chronic neurological dysfunction from stroke or TBI

A new ground-breaking study about to be published in the Adis journal CNS Drugs provides clinical evidence that, for the first time, chronic neurological dysfunction from stroke or traumatic brain injury can rapidly improve following a single dose of a drug that targets brain inflammation, even years after the stroke or traumatic event.

1 Nov 2012

Campaign trail issues and answers: Medicare reform, health law repeal still part of the mix

How is Medicare playing among the ever-important bloc of Florida senior citizens as the two presidential candidates vie for their votes? Similarly, it's also a hot topic in the Montana Senate race, which is one of the most intensely watched in the country.

1 Nov 2012

New shoe provides training control and prevents injuries during running

From the 80 million European runners, more than 37 million have suffered a running injury during sport practice in the last year. The Institute of Biomechanics of Valencia (IBV) is working on the design of a new running shoe that integrates a measuring device that will provide training control and prevent injuries during running.

1 Nov 2012

Controlling depression can improve health status and social functioning in patients with heart failure

Controlling depression in patients with heart failure can improve health status, social functioning and quality of life, according to a new study by psychiatrists and cardiologists at the UC Davis and Duke University schools of medicine.

1 Nov 2012

Scientists discover first selective inhibitors of DAGL enzymes

Scientists at The Scripps Research Institute (TSRI) have discovered the first selective inhibitors of an important set of enzymes. The new inhibitors, and chemical probes based on them, now can be used to study the functions of enzymes known as diacylglycerol lipases (DAGL), their products, and the pathways they regulate.

1 Nov 2012

FibroGen announces presentation of FG-4592 Phase 2 data on anemia at ASN Kidney Week 2012

FibroGen, Inc., today announced that two abstracts relating to FG-4592, its oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) clinical candidate for the treatment of anemia in chronic kidney disease, have been accepted for oral and poster presentations at the American Society of Nephrology (ASN) Kidney Week 2012.

1 Nov 2012

Ceramide might play a leading role in muscle deterioration in older adults

As men and women age, increasing quantities of fat tissue inevitably take up residence in skeletal muscle. A small study of older and younger men conducted at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University suggests that a build-up of a fat molecule known as ceramide might play a leading role in muscle deterioration in older adults.

1 Nov 2012

Varian highlights numerous lung cancer treatment systems at ASTRO meeting

Varian Medical Systems highlighted the company's technologies for the non-invasive treatment of lung cancer at the 54th annual meeting of the American Society for Radiation Oncology (ASTRO) in Boston this week.

1 Nov 2012

Isis announces preliminary data from ISIS-STAT3 Phase 1 study on cancer

Isis Pharmaceuticals, Inc. announced that preliminary data from the Phase 1 study of ISIS-STAT3Rx in patients with cancer were presented today at the Oligonucleotide Therapeutics Society in Boston.

1 Nov 2012

Chronic kidney disease associated with increased risk of death regardless of age

A new study from the Johns Hopkins Bloomberg School of Public Health and the Chronic Kidney Disease Prognosis Consortium found that chronic kidney disease and its complications were associated with a higher risk of death regardless of age.

1 Nov 2012

Additional data from EnVivo’s EVP-6124 Phase 2b trial on AD presented at CTAD meeting

EnVivo Pharmaceuticals, a company dedicated to developing a broad range of novel central nervous system (CNS) therapies, today presented pharmacokinetic and pharmacodynamic data along with the previously reported statistically significant clinical results from its Phase 2b clinical trial of EVP-6124, a novel alpha-7 agonist, in patients with Alzheimer's disease.

1 Nov 2012

Regular exercise does not impact amount of time women spend sitting

Women who exercise regularly spend as much time sitting as women who don't, according to a new Northwestern Medicine study.

1 Nov 2012

AKP America commences ART-123 Phase 3 trial in severe sepsis patients with coagulopathy

Asahi Kasei Pharma America Corp. today announced the initiation of an 800-patient Phase 3 clinical trial for ART-123 (recombinant human thrombomodulin, marketed as Recomodulin in Japan) in severe sepsis patients with coagulopathy.

1 Nov 2012

Medicare news: Health spending on seniors grew faster in U.S. than Canada; Plan to cut costs on dual eligibles raises questions

A new study finds that U.S. spending grew nearly three times faster since 1980 than Canada's spending on a similar population group.

1 Nov 2012

African American women coinfected with HIV and HCV less likely to die from liver disease than Caucasian or Hispanic women

A new study shows that African American women coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) are less likely to die from liver disease than Caucasian or Hispanic women.

31 Oct 2012

Access to malaria drugs transformed by new global subsidy

A new international scheme providing lifesaving antimalarial drugs at cheap subsidised prices has rapidly transformed access to effective artemisinin combination therapies (ACTs) in seven African countries accounting for a quarter of the world’s malaria cases, and could save millions of lives.

31 Oct 2012

Vitamin D and multiple sclerosis: an interview with Ellen Mowry

Vitamin D is actually a hormone. For the most part, humans obtain vitamin D through sun exposure. Ultraviolet light from the sun promotes the conversion of a compound in the skin to pre-vitamin D.

31 Oct 2012

Medical Condition News

Proposing standards and guidelines for Rett syndrome research

Study finds how effective healthcare can reduce toll from major diseases like stroke, cancer

Experimental HIV test might help improve diagnosis, treatment in developing countries

Single dose of etanercept can improve chronic neurological dysfunction from stroke or TBI

Campaign trail issues and answers: Medicare reform, health law repeal still part of the mix

New shoe provides training control and prevents injuries during running

Controlling depression can improve health status and social functioning in patients with heart failure

Scientists discover first selective inhibitors of DAGL enzymes

FibroGen announces presentation of FG-4592 Phase 2 data on anemia at ASN Kidney Week 2012

Ceramide might play a leading role in muscle deterioration in older adults

Varian highlights numerous lung cancer treatment systems at ASTRO meeting

Isis announces preliminary data from ISIS-STAT3 Phase 1 study on cancer

Chronic kidney disease associated with increased risk of death regardless of age

Additional data from EnVivo’s EVP-6124 Phase 2b trial on AD presented at CTAD meeting

Regular exercise does not impact amount of time women spend sitting

AKP America commences ART-123 Phase 3 trial in severe sepsis patients with coagulopathy

Medicare news: Health spending on seniors grew faster in U.S. than Canada; Plan to cut costs on dual eligibles raises questions

African American women coinfected with HIV and HCV less likely to die from liver disease than Caucasian or Hispanic women

Access to malaria drugs transformed by new global subsidy

Vitamin D and multiple sclerosis: an interview with Ellen Mowry

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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